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• W4288741346 endingPage "100459" @default.
• W4288741346 startingPage "100459" @default.
• W4288741346 abstract "The mutations of bacteria and viruses along with the resistance of various targets to the existing drugs have emerged as great challenges in the medical field. This imposes the need for novel drugs and medicines to resolve such threats. Metal complexes with thiosemicarbazone (TSC) and their derivatives have been reported to show good medicinal values and appear to be beneficial in terms of producing less toxic and more effective drugs. Literature shows that the metals have selectivity for the target cells and their coordination influences the binding of the ligand with proteins and enzymes. The present article gives an insight into the importance of coordination of TSC with transition and inner transition metals. It also correlates the variation in the biological activities with the nature of metal bound to the TSC and the presence of substituents attached to the TSC. Various explored derivatives of biologically active TSC – metal complexes have been reviewed. This paper establishes enhancement in the biological activity of different classes of metal- TSC derivative complexes compared to their precursors. We have tried to give details of the synergic effect of metal TSC complexes and propose their future use as combination drugs." @default.
• W4288741346 created "2022-07-30" @default.
• W4288741346 creator A5059021885 @default.
• W4288741346 creator A5073119281 @default.
• W4288741346 creator A5078681138 @default.
• W4288741346 creator A5083956143 @default.
• W4288741346 date "2022-01-01" @default.
• W4288741346 modified "2023-10-05" @default.
• W4288741346 title "Thiosemicarbazone derivatives of transition metals as multi-target drugs: A review" @default.
• W4288741346 cites W1498379503 @default.
• W4288741346 cites W1507765034 @default.
• W4288741346 cites W1553536221 @default.
• W4288741346 cites W1963762466 @default.
• W4288741346 cites W1967206984 @default.
• W4288741346 cites W1970218729 @default.
• W4288741346 cites W1972970311 @default.
• W4288741346 cites W1982254033 @default.
• W4288741346 cites W1982631958 @default.
• W4288741346 cites W1982846704 @default.
• W4288741346 cites W1983965827 @default.
• W4288741346 cites W1985076386 @default.
• W4288741346 cites W1986811948 @default.
• W4288741346 cites W1988971702 @default.
• W4288741346 cites W1990310588 @default.
• W4288741346 cites W1995386153 @default.
• W4288741346 cites W1997305691 @default.
• W4288741346 cites W2002498614 @default.
• W4288741346 cites W2005049480 @default.
• W4288741346 cites W2005877813 @default.
• W4288741346 cites W2006277511 @default.
• W4288741346 cites W2007330970 @default.
• W4288741346 cites W2007482864 @default.
• W4288741346 cites W2010054858 @default.
• W4288741346 cites W2011460644 @default.
• W4288741346 cites W2011537140 @default.
• W4288741346 cites W2011998213 @default.
• W4288741346 cites W2015620340 @default.
• W4288741346 cites W2016402859 @default.
• W4288741346 cites W2019999287 @default.
• W4288741346 cites W2026244671 @default.
• W4288741346 cites W2030279766 @default.
• W4288741346 cites W2035799084 @default.
• W4288741346 cites W2039988087 @default.
• W4288741346 cites W2040885378 @default.
• W4288741346 cites W2044130057 @default.
• W4288741346 cites W2047958094 @default.
• W4288741346 cites W2048412512 @default.
• W4288741346 cites W2048956809 @default.
• W4288741346 cites W2051568946 @default.
• W4288741346 cites W2053848533 @default.
• W4288741346 cites W2055192746 @default.
• W4288741346 cites W2058510526 @default.
• W4288741346 cites W2064163763 @default.
• W4288741346 cites W2065138621 @default.
• W4288741346 cites W2068026117 @default.
• W4288741346 cites W2069139836 @default.
• W4288741346 cites W2074962076 @default.
• W4288741346 cites W2076649326 @default.
• W4288741346 cites W2079405486 @default.
• W4288741346 cites W2081472473 @default.
• W4288741346 cites W2081551934 @default.
• W4288741346 cites W2087577568 @default.
• W4288741346 cites W2089718652 @default.
• W4288741346 cites W2090799784 @default.
• W4288741346 cites W2092767907 @default.
• W4288741346 cites W2094757071 @default.
• W4288741346 cites W2110489968 @default.
• W4288741346 cites W2126254284 @default.
• W4288741346 cites W2126508214 @default.
• W4288741346 cites W2138646392 @default.
• W4288741346 cites W2152622971 @default.
• W4288741346 cites W2157221159 @default.
• W4288741346 cites W2322223330 @default.
• W4288741346 cites W2322471495 @default.
• W4288741346 cites W2334203538 @default.
• W4288741346 cites W2467486430 @default.
• W4288741346 cites W2497531269 @default.
• W4288741346 cites W2559341640 @default.
• W4288741346 cites W2605358985 @default.
• W4288741346 cites W26722502 @default.
• W4288741346 cites W2781076747 @default.
• W4288741346 cites W2789475910 @default.
• W4288741346 cites W2801732910 @default.
• W4288741346 cites W2886710523 @default.
• W4288741346 cites W2896200923 @default.
• W4288741346 cites W2896860430 @default.
• W4288741346 cites W2898431283 @default.
• W4288741346 cites W2900233452 @default.
• W4288741346 cites W2903584670 @default.
• W4288741346 cites W2911586990 @default.
• W4288741346 cites W2922129109 @default.
• W4288741346 cites W2970667602 @default.
• W4288741346 cites W2976261203 @default.
• W4288741346 cites W3010342930 @default.
• W4288741346 cites W3035675081 @default.
• W4288741346 cites W3037057866 @default.
• W4288741346 cites W3093072707 @default.
• W4288741346 cites W3097506464 @default.

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