FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288942435> ?p ?o ?g. }

• W4288942435 endingPage "406" @default.
• W4288942435 startingPage "393" @default.
• W4288942435 abstract "Introduction: Morin hydrate (MH) is a bioflavonoid component of many fruits and vegetables. Our previous research demonstrated that MH provides neuroprotection in mouse models of acute restraint stress and sleep deprivation by attenuating hippocampal neuronal damage and enhancing memory. Based on these findings, our study investigated the role of MH in chronic stress-induced neuronal and biochemical perturbations in BALB/c mice. Methods: Male BALB/c mice were divided into 6 groups (n=6). Groups 1 and 2 received vehicle (10 mL/kg normal saline), groups 3-5 received MH (5, 10, 20 mg/kg IP), while group 6 received ginseng (25 mg/kg) daily and 30 minutes afterward were restrained in a plastic cylindrical restrainer for 14 days. Results: Immobility time in the forced swim test increased in the MH-treated group, indicating an antidepressant-like effect. Also, a reduction in frequency and duration of open arms exploration was observed in the elevated plus-maze (EPM) test in stressed mice, and administration of MH (5, 10, 20 mg/kg, IP) reversed these effects. An increase in blood levels of glucose, triglycerides, total cholesterol, and brain malondialdehyde and nitrite levels was observed in the stressed groups, which was reversed by MH. Furthermore, MH reversed the stress-induced reduction in HDL cholesterol and glutathione (GSH) levels and attenuated stress-induced alterations in the prefrontal cortex and hippocampus. Conclusion: Our findings suggest that MH attenuated chronic restraint stress-behavioral and biochemical perturbations, probably due to its capability to decrease oxidative stress and brain neuronal damage" @default.
• W4288942435 created "2022-07-31" @default.
• W4288942435 creator A5010288584 @default.
• W4288942435 creator A5061500612 @default.
• W4288942435 creator A5070880312 @default.
• W4288942435 creator A5081072737 @default.
• W4288942435 creator A5082363841 @default.
• W4288942435 date "2022-05-01" @default.
• W4288942435 modified "2023-10-14" @default.
• W4288942435 title "Ameliorating Effect of Morin Hydrate on Chronic Restraint Stress-induced Biochemical Disruption, Neuronal, and Behavioral Dysfunctions in BALB/c Mice" @default.
• W4288942435 cites W1189385401 @default.
• W4288942435 cites W1506043065 @default.
• W4288942435 cites W153384720 @default.
• W4288942435 cites W158220132 @default.
• W4288942435 cites W1864687269 @default.
• W4288942435 cites W1964160578 @default.
• W4288942435 cites W1965917653 @default.
• W4288942435 cites W1966259921 @default.
• W4288942435 cites W1972655436 @default.
• W4288942435 cites W1972860666 @default.
• W4288942435 cites W1975257396 @default.
• W4288942435 cites W1976014052 @default.
• W4288942435 cites W1981514736 @default.
• W4288942435 cites W1985496885 @default.
• W4288942435 cites W1987605932 @default.
• W4288942435 cites W1987785013 @default.
• W4288942435 cites W1991575496 @default.
• W4288942435 cites W1992420558 @default.
• W4288942435 cites W1998099581 @default.
• W4288942435 cites W2002147558 @default.
• W4288942435 cites W2007974392 @default.
• W4288942435 cites W2008901842 @default.
• W4288942435 cites W2013312860 @default.
• W4288942435 cites W2015914204 @default.
• W4288942435 cites W2020662867 @default.
• W4288942435 cites W2040638886 @default.
• W4288942435 cites W2041300408 @default.
• W4288942435 cites W2054536805 @default.
• W4288942435 cites W2054917107 @default.
• W4288942435 cites W2062636043 @default.
• W4288942435 cites W2064307316 @default.
• W4288942435 cites W2065398758 @default.
• W4288942435 cites W2067670322 @default.
• W4288942435 cites W2076269362 @default.
• W4288942435 cites W2078691062 @default.
• W4288942435 cites W2089189148 @default.
• W4288942435 cites W2096456417 @default.
• W4288942435 cites W2102178526 @default.
• W4288942435 cites W2102941764 @default.
• W4288942435 cites W2117925253 @default.
• W4288942435 cites W2120279490 @default.
• W4288942435 cites W2123290069 @default.
• W4288942435 cites W2144186309 @default.
• W4288942435 cites W2148573574 @default.
• W4288942435 cites W2149486086 @default.
• W4288942435 cites W2151024579 @default.
• W4288942435 cites W2155181385 @default.
• W4288942435 cites W2164012002 @default.
• W4288942435 cites W2197078876 @default.
• W4288942435 cites W2313854932 @default.
• W4288942435 cites W2412700258 @default.
• W4288942435 cites W2472781452 @default.
• W4288942435 cites W2561247095 @default.
• W4288942435 cites W2563745995 @default.
• W4288942435 cites W2778071177 @default.
• W4288942435 cites W2803308737 @default.
• W4288942435 cites W756325778 @default.
• W4288942435 doi "https://doi.org/10.32598/bcn.2022.1059.2" @default.
• W4288942435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36457885" @default.
• W4288942435 hasPublicationYear "2022" @default.
• W4288942435 type Work @default.
• W4288942435 citedByCount "0" @default.
• W4288942435 crossrefType "journal-article" @default.
• W4288942435 hasAuthorship W4288942435A5010288584 @default.
• W4288942435 hasAuthorship W4288942435A5061500612 @default.
• W4288942435 hasAuthorship W4288942435A5070880312 @default.
• W4288942435 hasAuthorship W4288942435A5081072737 @default.
• W4288942435 hasAuthorship W4288942435A5082363841 @default.
• W4288942435 hasBestOaLocation W42889424351 @default.
• W4288942435 hasConcept C126322002 @default.
• W4288942435 hasConcept C134018914 @default.
• W4288942435 hasConcept C136569192 @default.
• W4288942435 hasConcept C148762608 @default.
• W4288942435 hasConcept C15744967 @default.
• W4288942435 hasConcept C169760540 @default.
• W4288942435 hasConcept C169900460 @default.
• W4288942435 hasConcept C181199279 @default.
• W4288942435 hasConcept C185592680 @default.
• W4288942435 hasConcept C25498285 @default.
• W4288942435 hasConcept C2776151105 @default.
• W4288942435 hasConcept C2777397205 @default.
• W4288942435 hasConcept C2777981454 @default.
• W4288942435 hasConcept C2778401633 @default.
• W4288942435 hasConcept C2778654844 @default.
• W4288942435 hasConcept C2779177272 @default.
• W4288942435 hasConcept C2781161787 @default.
• W4288942435 hasConcept C2781195155 @default.
• W4288942435 hasConcept C2985495968 @default.

• next