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- W4288969935 abstract "Hyperlipidemia, particularly high low-density lipoprotein (LDL) cholesterol serum levels, represent an important risk factor for future cardiovascular events, showing both causal and cumulative effect on the threat of atherosclerotic cardiovascular disease [1]. LDL particles are fundamental for atheroma formation, through their capability to penetrate the vessel endothelial surface and accumulate into the intima. Progressive LDL accumulation, oxidation, and oxidized-LDL phagocytosis by monocyte-derived macrophages becoming foam cells, represent the initial step for atherosclerotic plaque development [1,2]." @default.
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- W4288969935 date "2022-10-01" @default.
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- W4288969935 title "Cholesterol crystals in atherosclerotic plaques: A future target to reduce the risk of plaque rupture?" @default.
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- W4288969935 doi "https://doi.org/10.1016/j.ijcard.2022.07.042" @default.
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