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- W4289131492 abstract "Deoxynivalenol (DON) is a type B trichothecene mycotoxin produced by Fusarium fungi. To investigate its ruminal degradability and its effect on rumen fermentation, a 2 × 5 factorial experiment was conducted in vitro with two feed substrates with different forage levels (high forage (HF), forage-to-concentrate = 4:1; low forage (LF), forage-to-concentrate = 1:4) and five DON additions per substrate (0, 5, 10, 15, and 20 mg/kg of dry matter). After 48 h incubation, the DON degradability in the HF group was higher than in the LF group (p < 0.01), and it decreased along with the increase in DON concentrations (p < 0.01), which varied from 57.18% to 29.01% at 48 h. In addition, the gas production rate, total VFA production and microbial crude protein decreased linearly against the increase in DON additions (p < 0.05). Meanwhile, the proportion of CH4 in the fermentation gas end-products increased linearly, especially in the HF group (p < 0.01). In brief, rumen microorganisms presented 29–57% of the DON degradation ability and were particularly significant under a high-forage substrate. Along with the increasing DON addition, the toxin degradability decreased, showing a dose-dependent response. However, DON inhibited rumen fermentation and increased methane production when it exceeded 5 mg/kg of dry matter." @default.
- W4289131492 created "2022-08-01" @default.
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- W4289131492 date "2022-07-31" @default.
- W4289131492 modified "2023-09-22" @default.
- W4289131492 title "Inhibitory Effect Mediated by Deoxynivalenol on Rumen Fermentation under High-Forage Substrate" @default.
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- W4289131492 doi "https://doi.org/10.3390/fermentation8080369" @default.
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