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- W4289145584 abstract "Transcranial direct current stimulation (tDCS) is known to have a modulatory effect on neural tissue and that it is polarity specific. It is also shown that tDCS demonstrated the lasting effect in therapeutic applications. The main aim of the study was to examine the effects of tDCS on cortical dynamics by analyzing EEG recordings. We applied here measures taken from Recurrence Quantification Analysis, Mean State Shift (MSS) and State Variance (SV) which were previously used to detect changes in brain-state dynamics after TMS. The studied cohort comprised of 16 healthy subjects; all subjects received anodal and cathodal tDCS, which were given in two separate sessions on the same day. The EEG was recorded from 10 electrodes, positioned over left motor cortex and mirroring right cortex corresponding to 10/20 standard. From three traces of recordings (pre, post1 and post2/before the stimulation, immediately after and 30min after tDCS) we extracted five different intervals (T1-T5) comprising of 500 samples. After calculating MSS and SV on those epochs and statistical testing for a significant difference, we applied Principal Component Analysis (PCA) on the same time series to check whether the data are separable. The results show that tDCS exert polarity specific effects on the MSS as shown by significantly lower MSS values after cathodal stimulation compared to anodal stimulation. Cathodal stimulation affected the SV, as compared to anodal stimulation, which did not lead to detectable changes. We are offering here for the first time an informative PCA visualization of a time-effect of a tDCS stimulation on brain state shift. Further research is needed to elucidate for how long that change can be detected and what neurobiological changes are introduced by that phenomena." @default.
- W4289145584 created "2022-08-01" @default.
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- W4289145584 date "2018-12-04" @default.
- W4289145584 modified "2023-09-28" @default.
- W4289145584 title "The Shift in brain-state induced by tDCS: an EEG study" @default.
- W4289145584 doi "https://doi.org/10.48550/arxiv.1812.01342" @default.
- W4289145584 hasPublicationYear "2018" @default.
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