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• W4289169925 abstract "The regulatory steps necessary to bring new PET radiopharmaceuticals to the clinic will be reviewed. The US Food and Drug Administration (FDA) provides approval to manufacture and use diagnostic radiopharmaceuticals, including those for cardiovascular PET/CT. Medicare not only provides insurance reimbursement for imaging procedures for its beneficiaries but also sets an example for third-party insurers to cover these procedures. FDA provides extensive guidance for performing studies to obtain the safety and efficacy data needed to approve PET radiopharmaceuticals, and the pace of approval has recently increased. There also has been considerable progress in insurance coverage for PET by Medicare. Several promising agents for cardiovascular PET imaging are in the development pipeline. Challenges remain, however, including low levels of reimbursement and the application of appropriate use criteria for imaging procedures. It is important for cardiologists to understand the regulatory steps involved in translating PET radiopharmaceuticals to the clinic. Recent progress in both FDA approvals and Medicare coverage should facilitate the clinical use of new PET agents for molecular imaging of the heart." @default.
• W4289169925 created "2022-08-01" @default.
• W4289169925 creator A5041065135 @default.
• W4289169925 date "2022-08-01" @default.
• W4289169925 modified "2023-09-25" @default.
• W4289169925 title "Regulatory Agencies and PET/CT Imaging in the Clinic" @default.
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• W4289169925 doi "https://doi.org/10.1007/s11886-022-01749-7" @default.
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