FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289174554> ?p ?o ?g. }

• W4289174554 endingPage "8445" @default.
• W4289174554 startingPage "8445" @default.
• W4289174554 abstract "The Vitamin D receptor (VDR) plays a key role in calcium homeostasis, as well as in cell proliferation and differentiation. Among the large number of VDR ligands that have been developed, we have previously shown that BXL-62 and Gemini-72, two C-20-modified vitamin D analogs are highly potent VDR agonists. In this study, we show that both VDR ligands restore the transcriptional activities of VDR variants unresponsive to the natural ligand and identified in patients with rickets. The elucidated mechanisms of action underlying the activities of these C-20-modified analogs emphasize the mutual adaptation of the ligand and the VDR ligand-binding pocket." @default.
• W4289174554 created "2022-08-01" @default.
• W4289174554 creator A5002590489 @default.
• W4289174554 creator A5005595984 @default.
• W4289174554 creator A5009508483 @default.
• W4289174554 creator A5009651349 @default.
• W4289174554 creator A5044165958 @default.
• W4289174554 creator A5047485184 @default.
• W4289174554 creator A5056661626 @default.
• W4289174554 creator A5070423452 @default.
• W4289174554 creator A5072897499 @default.
• W4289174554 date "2022-07-30" @default.
• W4289174554 modified "2023-10-16" @default.
• W4289174554 title "Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants" @default.
• W4289174554 cites W1979287544 @default.
• W4289174554 cites W1993652675 @default.
• W4289174554 cites W1997418235 @default.
• W4289174554 cites W2013431059 @default.
• W4289174554 cites W2015755792 @default.
• W4289174554 cites W2021555181 @default.
• W4289174554 cites W2024138777 @default.
• W4289174554 cites W2028079886 @default.
• W4289174554 cites W2030935023 @default.
• W4289174554 cites W2064141949 @default.
• W4289174554 cites W2065291224 @default.
• W4289174554 cites W2088072535 @default.
• W4289174554 cites W2092951411 @default.
• W4289174554 cites W2094523739 @default.
• W4289174554 cites W2101441882 @default.
• W4289174554 cites W2102013906 @default.
• W4289174554 cites W2102684666 @default.
• W4289174554 cites W2139654449 @default.
• W4289174554 cites W2144081223 @default.
• W4289174554 cites W2155746549 @default.
• W4289174554 cites W2166643952 @default.
• W4289174554 cites W2223565483 @default.
• W4289174554 cites W2315928423 @default.
• W4289174554 cites W2345874683 @default.
• W4289174554 cites W2520871375 @default.
• W4289174554 cites W2554025514 @default.
• W4289174554 cites W2593809406 @default.
• W4289174554 cites W2605046576 @default.
• W4289174554 cites W2790397185 @default.
• W4289174554 cites W2922650826 @default.
• W4289174554 cites W2956107260 @default.
• W4289174554 cites W3004668452 @default.
• W4289174554 cites W3185539987 @default.
• W4289174554 cites W4210675630 @default.
• W4289174554 cites W4248872320 @default.
• W4289174554 doi "https://doi.org/10.3390/ijms23158445" @default.
• W4289174554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35955580" @default.
• W4289174554 hasPublicationYear "2022" @default.
• W4289174554 type Work @default.
• W4289174554 citedByCount "1" @default.
• W4289174554 countsByYear W42891745542023 @default.
• W4289174554 crossrefType "journal-article" @default.
• W4289174554 hasAuthorship W4289174554A5002590489 @default.
• W4289174554 hasAuthorship W4289174554A5005595984 @default.
• W4289174554 hasAuthorship W4289174554A5009508483 @default.
• W4289174554 hasAuthorship W4289174554A5009651349 @default.
• W4289174554 hasAuthorship W4289174554A5044165958 @default.
• W4289174554 hasAuthorship W4289174554A5047485184 @default.
• W4289174554 hasAuthorship W4289174554A5056661626 @default.
• W4289174554 hasAuthorship W4289174554A5070423452 @default.
• W4289174554 hasAuthorship W4289174554A5072897499 @default.
• W4289174554 hasBestOaLocation W42891745541 @default.
• W4289174554 hasConcept C116569031 @default.
• W4289174554 hasConcept C124490489 @default.
• W4289174554 hasConcept C134018914 @default.
• W4289174554 hasConcept C170493617 @default.
• W4289174554 hasConcept C179639408 @default.
• W4289174554 hasConcept C185592680 @default.
• W4289174554 hasConcept C2776489590 @default.
• W4289174554 hasConcept C2776940978 @default.
• W4289174554 hasConcept C55493867 @default.
• W4289174554 hasConcept C71240020 @default.
• W4289174554 hasConcept C86803240 @default.
• W4289174554 hasConcept C95444343 @default.
• W4289174554 hasConcept C98274493 @default.
• W4289174554 hasConceptScore W4289174554C116569031 @default.
• W4289174554 hasConceptScore W4289174554C124490489 @default.
• W4289174554 hasConceptScore W4289174554C134018914 @default.
• W4289174554 hasConceptScore W4289174554C170493617 @default.
• W4289174554 hasConceptScore W4289174554C179639408 @default.
• W4289174554 hasConceptScore W4289174554C185592680 @default.
• W4289174554 hasConceptScore W4289174554C2776489590 @default.
• W4289174554 hasConceptScore W4289174554C2776940978 @default.
• W4289174554 hasConceptScore W4289174554C55493867 @default.
• W4289174554 hasConceptScore W4289174554C71240020 @default.
• W4289174554 hasConceptScore W4289174554C86803240 @default.
• W4289174554 hasConceptScore W4289174554C95444343 @default.
• W4289174554 hasConceptScore W4289174554C98274493 @default.
• W4289174554 hasFunder F4320320883 @default.
• W4289174554 hasFunder F4320321589 @default.
• W4289174554 hasIssue "15" @default.
• W4289174554 hasLocation W42891745541 @default.
• W4289174554 hasLocation W42891745542 @default.
• W4289174554 hasLocation W42891745543 @default.

• next