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- W4289204865 abstract "Parkinson's disease (PD) is the second-most prevalent neurodegenerative or neuropsychiatric disease, affecting 1% of seniors worldwide. The gut microbiota (GM) is one of the key access controls for most diseases and disorders. Disturbance in the GM creates an imbalance in the function and circulation of metabolites, resulting in unhealthy conditions. Any dysbiosis could affect the function of the gut, consequently disturbing the equilibrium in the intestine, and provoking pro-inflammatory conditions in the gut lumen, which send signals to the central nervous system (CNS) through the vagus enteric nervous system, possibly disturbing the blood-brain barrier. The neuroinflammatory conditions in the brain cause accumulation of α-syn, and progressively develop PD. An important aspect of understanding and treating the disease is access to broad knowledge about the influence of dietary supplements on GM. Probiotics are live microorganisms which, when administered in adequate amounts, confer a health benefit on the host. Probiotic supplementation improves the function of the CNS, and improves the motor and non-motor symptoms of PD. Probiotic supplementation could be an adjuvant therapeutic method to manage PD. This review summarizes the role of GM in health, the GM-brain axis, the pathogenesis of PD, the role of GM and diet in PD, and the influence of probiotic supplementation on PD. The study encourages further detailed clinical trials in PD patients with probiotics, which aids in determining the involvement of GM, intestinal mediators, and neurological mediators in the treatment or management of PD." @default.
- W4289204865 created "2022-08-01" @default.
- W4289204865 creator A5008454530 @default.
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- W4289204865 creator A5024388461 @default.
- W4289204865 creator A5069540900 @default.
- W4289204865 creator A5084413787 @default.
- W4289204865 date "2022-07-29" @default.
- W4289204865 modified "2023-09-30" @default.
- W4289204865 title "Role of the Gut–Brain Axis, Gut Microbial Composition, Diet, and Probiotic Intervention in Parkinson’s Disease" @default.
- W4289204865 cites W119783850 @default.
- W4289204865 cites W1432597522 @default.
- W4289204865 cites W147305297 @default.
- W4289204865 cites W1482873758 @default.
- W4289204865 cites W1490861410 @default.
- W4289204865 cites W14944598 @default.
- W4289204865 cites W1496790952 @default.
- W4289204865 cites W1515023627 @default.
- W4289204865 cites W1618714494 @default.
- W4289204865 cites W1682365470 @default.
- W4289204865 cites W1827132410 @default.
- W4289204865 cites W1837152578 @default.
- W4289204865 cites W1897759802 @default.
- W4289204865 cites W1903888485 @default.
- W4289204865 cites W1930598094 @default.
- W4289204865 cites W1934236512 @default.
- W4289204865 cites W1967111894 @default.
- W4289204865 cites W1968105193 @default.
- W4289204865 cites W1968791710 @default.
- W4289204865 cites W1968798502 @default.
- W4289204865 cites W1973082868 @default.
- W4289204865 cites W1974433379 @default.
- W4289204865 cites W1975691929 @default.
- W4289204865 cites W1976306764 @default.
- W4289204865 cites W1977198160 @default.
- W4289204865 cites W1977894295 @default.
- W4289204865 cites W1979308600 @default.
- W4289204865 cites W1980914602 @default.
- W4289204865 cites W1981266729 @default.
- W4289204865 cites W1981500982 @default.
- W4289204865 cites W1984870490 @default.
- W4289204865 cites W1987715985 @default.
- W4289204865 cites W1987992874 @default.
- W4289204865 cites W1988521942 @default.
- W4289204865 cites W1990663366 @default.
- W4289204865 cites W1992780204 @default.
- W4289204865 cites W199354732 @default.
- W4289204865 cites W1994424078 @default.
- W4289204865 cites W1995100225 @default.
- W4289204865 cites W1998395846 @default.
- W4289204865 cites W1998585277 @default.
- W4289204865 cites W2001339909 @default.
- W4289204865 cites W2001936050 @default.
- W4289204865 cites W2002840695 @default.
- W4289204865 cites W2002941870 @default.
- W4289204865 cites W2003673553 @default.
- W4289204865 cites W2007110604 @default.
- W4289204865 cites W2007115125 @default.
- W4289204865 cites W2008520672 @default.
- W4289204865 cites W2010055058 @default.
- W4289204865 cites W2011026492 @default.
- W4289204865 cites W2011719513 @default.
- W4289204865 cites W2019863741 @default.
- W4289204865 cites W2020647227 @default.
- W4289204865 cites W2023506796 @default.
- W4289204865 cites W2023818817 @default.
- W4289204865 cites W2026926998 @default.
- W4289204865 cites W2028184380 @default.
- W4289204865 cites W2030500910 @default.
- W4289204865 cites W2032157122 @default.
- W4289204865 cites W2032230795 @default.
- W4289204865 cites W2033829415 @default.
- W4289204865 cites W2035716309 @default.
- W4289204865 cites W2044908785 @default.
- W4289204865 cites W2048502267 @default.
- W4289204865 cites W2051517155 @default.
- W4289204865 cites W2054543134 @default.
- W4289204865 cites W2057179832 @default.
- W4289204865 cites W2057608998 @default.
- W4289204865 cites W2058801589 @default.
- W4289204865 cites W2060741641 @default.
- W4289204865 cites W2060776482 @default.
- W4289204865 cites W2063024868 @default.
- W4289204865 cites W2066176460 @default.
- W4289204865 cites W2067147530 @default.
- W4289204865 cites W2073449985 @default.
- W4289204865 cites W2076087096 @default.
- W4289204865 cites W2077590888 @default.
- W4289204865 cites W2079811188 @default.
- W4289204865 cites W2081041370 @default.
- W4289204865 cites W2082402714 @default.
- W4289204865 cites W2082704291 @default.
- W4289204865 cites W2084949910 @default.
- W4289204865 cites W2085022353 @default.
- W4289204865 cites W2086216523 @default.
- W4289204865 cites W2088170171 @default.
- W4289204865 cites W2089933763 @default.
- W4289204865 cites W2090058235 @default.