FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289205458> ?p ?o ?g. }

• W4289205458 endingPage "860" @default.
• W4289205458 startingPage "860" @default.
• W4289205458 abstract "(1) Background: direct-acting antivirals (DAA) are the current standard of care for chronic hepatitis C. Oncologic patients remain among the most difficult-to-treat subgroups of hepatitis C virus (HCV)-infected patients due to their clinical frailty and complex therapeutic protocols received. (2) Methods: we retrospectively collected and analysed clinical data of 30 consecutive patients treated with DAA, between 2015 and 2022, for chronic HCV infection in the context of oncologic disease. (3) Results: most patients were females (63.3%), median age was 67 years, HCV genotype 1 was prevalent (60%), and median HCV RNA levels were 2.2 × 106 IU/mL. The most common malignancy was breast cancer (37%), and the chief oncologic drugs co-administered with DAAs were tamoxifen, platinum derivatives, cyclophosphamide, paclitaxel, rituximab and doxorubicin. Overall, 50% of patients had chronic hepatitis. A total of 76.7% underwent a sofosbuvir-based treatment. Sustained virological response 12 weeks after the end of therapy (SVR12) was reached in all patients. After SVR12, two patients died. DAA treatment was well tolerated; no patients had to stop DAA treatment or showed any adverse event or drug-drug interaction specifically attributable to DAAs. (4) Conclusions: DAA treatment should be promptly offered to oncologic patients with chronic hepatitis C in order to achieve aminotransferase normalization and viremia control, making antineoplastic therapy feasible and safe." @default.
• W4289205458 created "2022-08-01" @default.
• W4289205458 creator A5040032392 @default.
• W4289205458 creator A5052142949 @default.
• W4289205458 creator A5053730243 @default.
• W4289205458 creator A5060115502 @default.
• W4289205458 creator A5063118179 @default.
• W4289205458 creator A5066445066 @default.
• W4289205458 creator A5074442365 @default.
• W4289205458 creator A5088820395 @default.
• W4289205458 date "2022-07-29" @default.
• W4289205458 modified "2023-10-03" @default.
• W4289205458 title "Safety and Efficacy of Direct Antiviral Agents for Hepatitis C in Patients with Malignancies Other Than Liver Cancer: A Case Series" @default.
• W4289205458 cites W1998417747 @default.
• W4289205458 cites W2003104968 @default.
• W4289205458 cites W2075816945 @default.
• W4289205458 cites W2104010560 @default.
• W4289205458 cites W2123214161 @default.
• W4289205458 cites W2185218296 @default.
• W4289205458 cites W2520293475 @default.
• W4289205458 cites W2531439807 @default.
• W4289205458 cites W2732983362 @default.
• W4289205458 cites W2735359208 @default.
• W4289205458 cites W2740336755 @default.
• W4289205458 cites W2762048449 @default.
• W4289205458 cites W2794154499 @default.
• W4289205458 cites W2884724273 @default.
• W4289205458 cites W2899784297 @default.
• W4289205458 cites W2911509053 @default.
• W4289205458 cites W2938255138 @default.
• W4289205458 cites W2979590060 @default.
• W4289205458 cites W2995322872 @default.
• W4289205458 cites W3030657981 @default.
• W4289205458 cites W3088020815 @default.
• W4289205458 cites W3092757581 @default.
• W4289205458 cites W3156271714 @default.
• W4289205458 cites W3159511411 @default.
• W4289205458 cites W4211051574 @default.
• W4289205458 cites W4211243282 @default.
• W4289205458 cites W4223956747 @default.
• W4289205458 doi "https://doi.org/10.3390/pathogens11080860" @default.
• W4289205458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36014981" @default.
• W4289205458 hasPublicationYear "2022" @default.
• W4289205458 type Work @default.
• W4289205458 citedByCount "1" @default.
• W4289205458 countsByYear W42892054582023 @default.
• W4289205458 crossrefType "journal-article" @default.
• W4289205458 hasAuthorship W4289205458A5040032392 @default.
• W4289205458 hasAuthorship W4289205458A5052142949 @default.
• W4289205458 hasAuthorship W4289205458A5053730243 @default.
• W4289205458 hasAuthorship W4289205458A5060115502 @default.
• W4289205458 hasAuthorship W4289205458A5063118179 @default.
• W4289205458 hasAuthorship W4289205458A5066445066 @default.
• W4289205458 hasAuthorship W4289205458A5074442365 @default.
• W4289205458 hasAuthorship W4289205458A5088820395 @default.
• W4289205458 hasBestOaLocation W42892054581 @default.
• W4289205458 hasConcept C121608353 @default.
• W4289205458 hasConcept C126322002 @default.
• W4289205458 hasConcept C143998085 @default.
• W4289205458 hasConcept C197934379 @default.
• W4289205458 hasConcept C203014093 @default.
• W4289205458 hasConcept C2522874641 @default.
• W4289205458 hasConcept C2776231280 @default.
• W4289205458 hasConcept C2776408679 @default.
• W4289205458 hasConcept C2776455275 @default.
• W4289205458 hasConcept C2778375690 @default.
• W4289205458 hasConcept C2778390639 @default.
• W4289205458 hasConcept C2780040827 @default.
• W4289205458 hasConcept C530470458 @default.
• W4289205458 hasConcept C71924100 @default.
• W4289205458 hasConcept C90924648 @default.
• W4289205458 hasConceptScore W4289205458C121608353 @default.
• W4289205458 hasConceptScore W4289205458C126322002 @default.
• W4289205458 hasConceptScore W4289205458C143998085 @default.
• W4289205458 hasConceptScore W4289205458C197934379 @default.
• W4289205458 hasConceptScore W4289205458C203014093 @default.
• W4289205458 hasConceptScore W4289205458C2522874641 @default.
• W4289205458 hasConceptScore W4289205458C2776231280 @default.
• W4289205458 hasConceptScore W4289205458C2776408679 @default.
• W4289205458 hasConceptScore W4289205458C2776455275 @default.
• W4289205458 hasConceptScore W4289205458C2778375690 @default.
• W4289205458 hasConceptScore W4289205458C2778390639 @default.
• W4289205458 hasConceptScore W4289205458C2780040827 @default.
• W4289205458 hasConceptScore W4289205458C530470458 @default.
• W4289205458 hasConceptScore W4289205458C71924100 @default.
• W4289205458 hasConceptScore W4289205458C90924648 @default.
• W4289205458 hasIssue "8" @default.
• W4289205458 hasLocation W42892054581 @default.
• W4289205458 hasLocation W42892054582 @default.
• W4289205458 hasLocation W42892054583 @default.
• W4289205458 hasOpenAccess W4289205458 @default.
• W4289205458 hasPrimaryLocation W42892054581 @default.
• W4289205458 hasRelatedWork W2091876178 @default.
• W4289205458 hasRelatedWork W2114705120 @default.
• W4289205458 hasRelatedWork W2258641314 @default.
• W4289205458 hasRelatedWork W2522970322 @default.
• W4289205458 hasRelatedWork W2584621488 @default.
• W4289205458 hasRelatedWork W2806466804 @default.

• next