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- W4289225126 abstract "Panax quinquefolius L. has attracted extensive attention worldwide because of its prominent pharmacological properties on type 2 diabetes, cancers, central nervous system, and cardiovascular diseases. Ginsenosides are active phytochemicals of P. quinquefolius , which can be classified as propanaxdiol (PPD)-type, propanaxtriol (PPT)-type, oleanane-type, and ocotillol-type oligo-glycosides depending on the skeleton of aglycone. Recently, advanced analytical and isolated methods including ultra-performance liquid chromatography tandem with mass detector, preparative high-performance liquid chromatography, and high speed counter-current chromatography have been used to isolate and identify minor components in P. quinquefolius , which accelerates the clarification of the material basis. However, the poor bioavailability and undetermined bio-metabolism of most saponins have greatly hindered both the development of medicines and the identification of their real active constituents. Thus, it is essential to consider the bio-metabolism of constituents before and after absorption. In this review, we described the structures of minor ginsenosides in P. quinquefolius , including naturally occurring protype compounds and their in vivo metabolites. The preclinical and clinical pharmacological studies of the ginsenosides in the past few years were also summarized. The review will promote the reacquaint of minor saponins on the growing appreciation of their biological role in P. quinquefolius ." @default.
- W4289225126 created "2022-08-01" @default.
- W4289225126 creator A5005914218 @default.
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- W4289225126 creator A5049180121 @default.
- W4289225126 creator A5054349869 @default.
- W4289225126 creator A5068396282 @default.
- W4289225126 creator A5073938530 @default.
- W4289225126 creator A5074941694 @default.
- W4289225126 date "2022-08-01" @default.
- W4289225126 modified "2023-09-30" @default.
- W4289225126 title "A review for discovering bioactive minor saponins and biotransformative metabolites in Panax quinquefolius L." @default.
- W4289225126 cites W1412633253 @default.
- W4289225126 cites W1900692297 @default.
- W4289225126 cites W1970527699 @default.
- W4289225126 cites W1975714310 @default.
- W4289225126 cites W1975717671 @default.
- W4289225126 cites W1981386921 @default.
- W4289225126 cites W1985733683 @default.
- W4289225126 cites W1987257724 @default.
- W4289225126 cites W1988375066 @default.
- W4289225126 cites W1989878038 @default.
- W4289225126 cites W1990010386 @default.
- W4289225126 cites W1992679710 @default.
- W4289225126 cites W1993124588 @default.
- W4289225126 cites W1993726050 @default.
- W4289225126 cites W1996913578 @default.
- W4289225126 cites W2001962823 @default.
- W4289225126 cites W2002268116 @default.
- W4289225126 cites W2003838432 @default.
- W4289225126 cites W2005942501 @default.
- W4289225126 cites W2009077396 @default.
- W4289225126 cites W2009294571 @default.
- W4289225126 cites W2022579077 @default.
- W4289225126 cites W2023339504 @default.
- W4289225126 cites W2032567575 @default.
- W4289225126 cites W2036644016 @default.
- W4289225126 cites W2036907390 @default.
- W4289225126 cites W2040461083 @default.
- W4289225126 cites W2042134944 @default.
- W4289225126 cites W2050715601 @default.
- W4289225126 cites W2053656819 @default.
- W4289225126 cites W2054064635 @default.
- W4289225126 cites W2071025430 @default.
- W4289225126 cites W2071999004 @default.
- W4289225126 cites W2073031522 @default.
- W4289225126 cites W2077163851 @default.
- W4289225126 cites W2080402431 @default.
- W4289225126 cites W2083563142 @default.
- W4289225126 cites W2084129454 @default.
- W4289225126 cites W2086131363 @default.
- W4289225126 cites W2088892962 @default.
- W4289225126 cites W2094720733 @default.
- W4289225126 cites W2095292051 @default.
- W4289225126 cites W2109902553 @default.
- W4289225126 cites W2110413597 @default.
- W4289225126 cites W2116144169 @default.
- W4289225126 cites W2130544703 @default.
- W4289225126 cites W2134164391 @default.
- W4289225126 cites W2136127760 @default.
- W4289225126 cites W2137444447 @default.
- W4289225126 cites W2144608174 @default.
- W4289225126 cites W2151094628 @default.
- W4289225126 cites W2152123492 @default.
- W4289225126 cites W2157155711 @default.
- W4289225126 cites W2197805654 @default.
- W4289225126 cites W2217939904 @default.
- W4289225126 cites W2224492194 @default.
- W4289225126 cites W2233745169 @default.
- W4289225126 cites W2272169016 @default.
- W4289225126 cites W2319013217 @default.
- W4289225126 cites W2324845973 @default.
- W4289225126 cites W2337506600 @default.
- W4289225126 cites W2419679125 @default.
- W4289225126 cites W2514916327 @default.
- W4289225126 cites W2560233139 @default.
- W4289225126 cites W2594850080 @default.
- W4289225126 cites W2594900992 @default.
- W4289225126 cites W2603512694 @default.
- W4289225126 cites W2606081795 @default.
- W4289225126 cites W2725518188 @default.
- W4289225126 cites W2734417693 @default.
- W4289225126 cites W2762708658 @default.
- W4289225126 cites W2783881039 @default.
- W4289225126 cites W2789003854 @default.
- W4289225126 cites W2898601972 @default.
- W4289225126 cites W2907054137 @default.
- W4289225126 cites W2944560690 @default.
- W4289225126 cites W2944596632 @default.
- W4289225126 cites W2964495094 @default.
- W4289225126 cites W2986805167 @default.
- W4289225126 cites W3011317976 @default.
- W4289225126 cites W3011849538 @default.
- W4289225126 cites W3054040782 @default.
- W4289225126 cites W3120409918 @default.
- W4289225126 cites W3180247518 @default.
- W4289225126 cites W3205472876 @default.
- W4289225126 cites W4200253045 @default.
- W4289225126 cites W4200307097 @default.
- W4289225126 cites W4332041 @default.