FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289346312> ?p ?o ?g. }

• W4289346312 endingPage "1657" @default.
• W4289346312 startingPage "1645" @default.
• W4289346312 abstract "The use of predictive low-glucose suspend (PLGS) sensor-augmented pumps has been shown to lead to a significant reduction in hypoglycemic episodes in patients with type 1 diabetes (T1D), but their effects on hyperglycemia exposure are heterogeneous. The aim of this study was to determine the settings of the Medtronic 640G system to obtain the optimal balance between occurrence of both hypoglycemia and hyperglycemia.The hypo- and hyperglycemia area under the curve (AUC), as well as system settings [hypoglycemic threshold, mean insulin total daily dose (TDD), mean basal insulin percentage, and mean daily duration of PLGS] were collected between 2 and 12 times during 1 year in patients from four university hospital centers. Univariate/multivariate analyses and receiver operating characteristics (ROC) curves were performed to determine factors associated with hyper- and hypoglycemia AUC.A total of 864 observations were analyzed from 110 patients with T1D. Two preselected settings predictive of low hyperglycemia AUC were a basal insulin percentage < 52.0% [sensitivity (Se) = 0.66 and specificity (Sp) = 0.53] and a PLGS duration > 157.5 min/day (Se = 0.47 and Sp = 0.73). The preselected setting predictive of a low hypoglycemia AUC was a PLGS duration ≤ 174.4 min (Se = 0.83 and Sp = 0.51). Between-visit variation of PLGS and TDD was positively correlated (r = 0.61; p < 0.0001).The most important Medtronic 640G setting was the mean daily PLGS duration, where a value between 157.5 and 174.4 min/day was associated with the best reduction in both hypo- and hyperglycemia AUC. In this study, we showed that PLGS duration could be indirectly modified through total daily insulin dose adaptation.This study is registered in clinicaltrials.gov (NCT03047486)." @default.
• W4289346312 created "2022-08-02" @default.
• W4289346312 creator A5000143782 @default.
• W4289346312 creator A5011866397 @default.
• W4289346312 creator A5020610587 @default.
• W4289346312 creator A5028556868 @default.
• W4289346312 creator A5029201551 @default.
• W4289346312 creator A5064287355 @default.
• W4289346312 creator A5067198020 @default.
• W4289346312 creator A5084556936 @default.
• W4289346312 creator A5086505230 @default.
• W4289346312 date "2022-08-01" @default.
• W4289346312 modified "2023-10-18" @default.
• W4289346312 title "Sensor-Augmented Insulin Pump with Predictive Low-Glucose Suspend (PLGS): Determining Optimal Settings of Pump and Sensor in a Multicenter Cohort of Patients with Type 1 Diabetes" @default.
• W4289346312 cites W2072819500 @default.
• W4289346312 cites W2330613462 @default.
• W4289346312 cites W2597871801 @default.
• W4289346312 cites W2615150331 @default.
• W4289346312 cites W2734661081 @default.
• W4289346312 cites W2773647477 @default.
• W4289346312 cites W2802855656 @default.
• W4289346312 cites W2886691517 @default.
• W4289346312 cites W2893535289 @default.
• W4289346312 cites W2897839932 @default.
• W4289346312 cites W2943761611 @default.
• W4289346312 cites W2946917435 @default.
• W4289346312 cites W2963316214 @default.
• W4289346312 cites W2973481456 @default.
• W4289346312 cites W3010757859 @default.
• W4289346312 cites W3020963443 @default.
• W4289346312 cites W4233732280 @default.
• W4289346312 cites W4254445254 @default.
• W4289346312 doi "https://doi.org/10.1007/s13300-022-01302-3" @default.
• W4289346312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35913656" @default.
• W4289346312 hasPublicationYear "2022" @default.
• W4289346312 type Work @default.
• W4289346312 citedByCount "0" @default.
• W4289346312 crossrefType "journal-article" @default.
• W4289346312 hasAuthorship W4289346312A5000143782 @default.
• W4289346312 hasAuthorship W4289346312A5011866397 @default.
• W4289346312 hasAuthorship W4289346312A5020610587 @default.
• W4289346312 hasAuthorship W4289346312A5028556868 @default.
• W4289346312 hasAuthorship W4289346312A5029201551 @default.
• W4289346312 hasAuthorship W4289346312A5064287355 @default.
• W4289346312 hasAuthorship W4289346312A5067198020 @default.
• W4289346312 hasAuthorship W4289346312A5084556936 @default.
• W4289346312 hasAuthorship W4289346312A5086505230 @default.
• W4289346312 hasBestOaLocation W42893463121 @default.
• W4289346312 hasConcept C112705442 @default.
• W4289346312 hasConcept C126322002 @default.
• W4289346312 hasConcept C134018914 @default.
• W4289346312 hasConcept C2777180221 @default.
• W4289346312 hasConcept C2778024521 @default.
• W4289346312 hasConcept C2779306644 @default.
• W4289346312 hasConcept C2779794567 @default.
• W4289346312 hasConcept C2780668416 @default.
• W4289346312 hasConcept C2781232474 @default.
• W4289346312 hasConcept C2909524832 @default.
• W4289346312 hasConcept C2986379492 @default.
• W4289346312 hasConcept C3020225094 @default.
• W4289346312 hasConcept C555293320 @default.
• W4289346312 hasConcept C58471807 @default.
• W4289346312 hasConcept C71924100 @default.
• W4289346312 hasConcept C72563966 @default.
• W4289346312 hasConcept C76318530 @default.
• W4289346312 hasConceptScore W4289346312C112705442 @default.
• W4289346312 hasConceptScore W4289346312C126322002 @default.
• W4289346312 hasConceptScore W4289346312C134018914 @default.
• W4289346312 hasConceptScore W4289346312C2777180221 @default.
• W4289346312 hasConceptScore W4289346312C2778024521 @default.
• W4289346312 hasConceptScore W4289346312C2779306644 @default.
• W4289346312 hasConceptScore W4289346312C2779794567 @default.
• W4289346312 hasConceptScore W4289346312C2780668416 @default.
• W4289346312 hasConceptScore W4289346312C2781232474 @default.
• W4289346312 hasConceptScore W4289346312C2909524832 @default.
• W4289346312 hasConceptScore W4289346312C2986379492 @default.
• W4289346312 hasConceptScore W4289346312C3020225094 @default.
• W4289346312 hasConceptScore W4289346312C555293320 @default.
• W4289346312 hasConceptScore W4289346312C58471807 @default.
• W4289346312 hasConceptScore W4289346312C71924100 @default.
• W4289346312 hasConceptScore W4289346312C72563966 @default.
• W4289346312 hasConceptScore W4289346312C76318530 @default.
• W4289346312 hasFunder F4320307813 @default.
• W4289346312 hasIssue "9" @default.
• W4289346312 hasLocation W42893463121 @default.
• W4289346312 hasLocation W42893463122 @default.
• W4289346312 hasLocation W42893463123 @default.
• W4289346312 hasOpenAccess W4289346312 @default.
• W4289346312 hasPrimaryLocation W42893463121 @default.
• W4289346312 hasRelatedWork W1984139024 @default.
• W4289346312 hasRelatedWork W1995747568 @default.
• W4289346312 hasRelatedWork W2016328345 @default.
• W4289346312 hasRelatedWork W2042819106 @default.
• W4289346312 hasRelatedWork W2048226041 @default.
• W4289346312 hasRelatedWork W2066345847 @default.
• W4289346312 hasRelatedWork W2068166803 @default.
• W4289346312 hasRelatedWork W2430205611 @default.
• W4289346312 hasRelatedWork W3016082013 @default.

• next