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- W4289352734 abstract "Background: Urothethiasis is the most common urinary tract disease with a global prevalencerate of 2-20%. Alfa-blocker has a relaxation effect on the smooth muscles of the ureter making theremoval of ureteric stone easier during the ureteroscopic procedure.Objectives: To evaluate the effect of preoperative -adrenoreceptor antagonists therapy (tamsulosin) in the treatment of ureteral stone using a ureteroscope regarding operative time, access tothe ureter, and the complication rate.Materials and methods: A prospective case-control study was conducted at Al-JamhoryTeaching Hospital, Mosul, Iraq. During the period from June 2019 to August 2020. Subjectts withureteral stones (7-15 mm) scheduled for ureteroscopic intervention were enrolled in the study. Thepatients were classified into two groups, the first group was received a pre-operative alpha-blocker(tamsulosin 0.4 mg capsule per day for 7 days), and the second group (Control) did not receivefurther medication. The operative time, uretric access, and intra- and postoperative complicationswere registered for both groups.Results: There was a matching between the two groups regarding the age, gender, and side, size,and location of the ureteric stones. There was a statistically significant difference between the twogroups regarding the operative time (23.2 ± 4.569 minute in the treated group vs. 25.48 ± 4.904minute in the control group) (P-value = 0.009). Besides, the ureteroscopic operation was easier(P-value = 0.031) in treated group (n = 51 easy case, 85%) than the control group (n=41, 68.33%easy case). The intraoperative and postoperative complications were mucosal injury, perforation,bleeding, pain, hematuria, and fever. The total number of complicated cases was 14 (23.33%) inthe treated group and 25 (41.66%) in the control group, and there was a significant differencebetween the two groups (P-value = 0.032).Conclusion: The study revealed that the preoperative alpha-blocker tamsulosin was improved theoutcome of ureteroscopy (shorter operative time, easier access to the ureter, and low complicationrate)." @default.
- W4289352734 created "2022-08-02" @default.
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- W4289352734 date "2022-06-01" @default.
- W4289352734 modified "2023-10-18" @default.
- W4289352734 title "Effect of Preoperative Alpha-Blocker in Ureteroscopy for Ureteral Stones: A Case-Control Study" @default.
- W4289352734 doi "https://doi.org/10.33091/amj.2021.174524" @default.
- W4289352734 hasPublicationYear "2022" @default.
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