Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289466262> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4289466262 endingPage "29" @default.
- W4289466262 startingPage "23" @default.
- W4289466262 abstract "The First apoptosis signal (FAS) and First apoptosis signal ligand (FASL) genes initiate the apoptosis pathway, playing a central role in the tumor growth and metastasis. Gene polymorphisms including -1377 G/A in the promoter region of FAS and -844 C/T in the promoter region of FASL have shown to change the transcription activities of these genes.In this study we evaluated association of these polymorphisms with risk of metastasis of breast cancer, in a population selected from Mashhad, Iran. A total of 115 patients with breast cancer and 115 controls were recruited in this case-control study. Polymerase Chain Reaction-based Restriction Fragment Length Polymorphism (PCR-RFLP) was applied for genotyping on extracted DNA from participant's blood. Unconditional logistic regression was used to estimate cancer risk by calculating odds ratios (OR) and their 95% confidence intervals (95% CIs).There was no significant association between these genetic polymorphisms and breast cancer risk. Additionally, our results showed no significant influence from the above mentioned gene polymorphisms on metastasis of breast cancer.These results suggest that the FAS-1377G/A and FASL-844 C/T gene polymorphism don't have much influence on the susceptibility to metastasis of breast cancer in northeastern Iranian population. Therefore, we suggest to investigate impact of other candidate gene polymorphisms on metastasis of breast cancer for future research." @default.
- W4289466262 created "2022-08-02" @default.
- W4289466262 creator A5017947632 @default.
- W4289466262 creator A5032201575 @default.
- W4289466262 creator A5038040323 @default.
- W4289466262 creator A5043541713 @default.
- W4289466262 creator A5051135510 @default.
- W4289466262 creator A5063825582 @default.
- W4289466262 date "2018-10-01" @default.
- W4289466262 modified "2023-09-29" @default.
- W4289466262 title "Status of FAS and FAS Ligand Gene Polymorphisms in Patients with Breast Cancer in Northeastern IRAN." @default.
- W4289466262 cites W1965597184 @default.
- W4289466262 cites W1969770991 @default.
- W4289466262 cites W1971873029 @default.
- W4289466262 cites W1974460143 @default.
- W4289466262 cites W1986331114 @default.
- W4289466262 cites W1990327132 @default.
- W4289466262 cites W1998017001 @default.
- W4289466262 cites W1998576236 @default.
- W4289466262 cites W2010000042 @default.
- W4289466262 cites W2033973638 @default.
- W4289466262 cites W2063411685 @default.
- W4289466262 cites W2077933717 @default.
- W4289466262 cites W2079607578 @default.
- W4289466262 cites W2080491234 @default.
- W4289466262 cites W2091121957 @default.
- W4289466262 cites W2092362867 @default.
- W4289466262 cites W2097130546 @default.
- W4289466262 cites W2112656712 @default.
- W4289466262 cites W2112901167 @default.
- W4289466262 cites W2118299978 @default.
- W4289466262 cites W2127863924 @default.
- W4289466262 cites W2131695469 @default.
- W4289466262 cites W2137694849 @default.
- W4289466262 cites W2150043714 @default.
- W4289466262 cites W2150246065 @default.
- W4289466262 cites W2154333430 @default.
- W4289466262 cites W2158558392 @default.
- W4289466262 cites W2161817637 @default.
- W4289466262 cites W2170507464 @default.
- W4289466262 cites W2173858545 @default.
- W4289466262 cites W2317564428 @default.
- W4289466262 cites W2330979714 @default.
- W4289466262 cites W2230483107 @default.
- W4289466262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30324114" @default.
- W4289466262 hasPublicationYear "2018" @default.
- W4289466262 type Work @default.
- W4289466262 citedByCount "2" @default.
- W4289466262 countsByYear W42894662622021 @default.
- W4289466262 countsByYear W42894662622022 @default.
- W4289466262 crossrefType "journal-article" @default.
- W4289466262 hasAuthorship W4289466262A5017947632 @default.
- W4289466262 hasAuthorship W4289466262A5032201575 @default.
- W4289466262 hasAuthorship W4289466262A5038040323 @default.
- W4289466262 hasAuthorship W4289466262A5043541713 @default.
- W4289466262 hasAuthorship W4289466262A5051135510 @default.
- W4289466262 hasAuthorship W4289466262A5063825582 @default.
- W4289466262 hasConcept C104317684 @default.
- W4289466262 hasConcept C121608353 @default.
- W4289466262 hasConcept C126322002 @default.
- W4289466262 hasConcept C143998085 @default.
- W4289466262 hasConcept C190283241 @default.
- W4289466262 hasConcept C31573885 @default.
- W4289466262 hasConcept C502942594 @default.
- W4289466262 hasConcept C530470458 @default.
- W4289466262 hasConcept C54355233 @default.
- W4289466262 hasConcept C66008609 @default.
- W4289466262 hasConcept C71924100 @default.
- W4289466262 hasConcept C86803240 @default.
- W4289466262 hasConceptScore W4289466262C104317684 @default.
- W4289466262 hasConceptScore W4289466262C121608353 @default.
- W4289466262 hasConceptScore W4289466262C126322002 @default.
- W4289466262 hasConceptScore W4289466262C143998085 @default.
- W4289466262 hasConceptScore W4289466262C190283241 @default.
- W4289466262 hasConceptScore W4289466262C31573885 @default.
- W4289466262 hasConceptScore W4289466262C502942594 @default.
- W4289466262 hasConceptScore W4289466262C530470458 @default.
- W4289466262 hasConceptScore W4289466262C54355233 @default.
- W4289466262 hasConceptScore W4289466262C66008609 @default.
- W4289466262 hasConceptScore W4289466262C71924100 @default.
- W4289466262 hasConceptScore W4289466262C86803240 @default.
- W4289466262 hasIssue "1" @default.
- W4289466262 hasLocation W42894662621 @default.
- W4289466262 hasOpenAccess W4289466262 @default.
- W4289466262 hasPrimaryLocation W42894662621 @default.
- W4289466262 hasVolume "7" @default.
- W4289466262 isParatext "false" @default.
- W4289466262 isRetracted "false" @default.
- W4289466262 workType "article" @default.