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• W4289551830 abstract "Autism spectrum disorder (ASD) is a neurodevelopmental illness that leads to repetitive behavior and debilitates social communication. Genetic changes such as susceptible genes and environmental factors promote ASD pathogenesis. Mutations in neuroligins (NLGNs) and neurexin (NRXNs) complex which encode cell adhesion molecules have a significant part in synapses formation, transcription, and excitatory–inhibitory balance. The ASD pathogenesis could partly, at the least, be related to synaptic dysfunction. Here, the NRXNs and NLGNs genes and signaling pathways involved in the synaptic malfunction that causes ASD have been reviewed. Besides, a new insight of NLGNs and NRXNs genes in ASD will be conferred." @default.
• W4289551830 created "2022-08-03" @default.
• W4289551830 creator A5038666435 @default.
• W4289551830 date "2023-01-01" @default.
• W4289551830 modified "2023-09-30" @default.
• W4289551830 title "Implications of cell adhesion molecules in autism spectrum disorder pathogenesis" @default.
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• W4289551830 doi "https://doi.org/10.4103/jmau.jmau_15_22" @default.
• W4289551830 hasPublicationYear "2023" @default.
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