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- W4289638073 abstract "The posterior HOXD enhancer is an EWSR1::FLI1-dependent regulator of HOXD13 expression in Ewing sarcoma. HOXD13 expression promotes a mesenchymal cell state. Through antagonistic transcriptional programs, EWSR1::FLI1 and HOXD13 serve as master regulators of Ewing cell plasticity. Targeting Ewing cells as they exist in/transition between mesenchymal states is a priority. See related article by Apfelbaum et al., p. 4466." @default.
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- W4289638073 date "2022-08-03" @default.
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- W4289638073 title "A Druggable Rheostat for Ewing Sarcoma?" @default.
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- W4289638073 doi "https://doi.org/10.1158/1078-0432.ccr-22-1794" @default.
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