Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289731333> ?p ?o ?g. }
- W4289731333 abstract "Background and objective Growth differentiation factor-15 (GDF-15) and fibroblast growth factor-23 (FGF-23) are considered predictors of the incidence of cardiovascular diseases. The present meta-analysis aimed to elucidate the associations between GDF-15 and FGF-23 in the risk of atrial fibrillation (AF). Methods An electronic search was conducted in the Cochrane Library, PubMed, and Embase databases from inception until February 27, 2021. The study protocol was registered in the PROSPERO database (CRD42020182226). Results In total, 15 studies that enrolled 36,017 participants were included. Both serum FGF-23 and GDF-15 were elevated in patients with AF. Analysis of categorical variables showed higher serum FGF-23 levels were associated with an increased risk of AF [relative risk (RR) = 1.28, 95% confidence interval (CI): 1.05–1.56]. In contrast, this association was not found with GDF-15 (RR = 0.91, 95% CI: 0.20–4.04). In dose-response analysis, a linear positive association was noted between serum FGF-23 levels and the risk of AF (P nonlinear = 0.9507), with a RR elevation of 7% for every 20 pg/ml increase in the serum FGF-23 levels (95% CI: 1.02–1.13). No remarkable relationship was found between serum GDF-15 levels and the risk of AF, and the overall RR for the association between a 100 ng/L increment in GDF-15 levels and AF was 1.01 (95% CI: 0.998–1.02). Conclusion Our study showed a positive linear correlation between serum FGF-23 levels and the risk of AF. However, no significant association was found between GDF-15 and the risk of AF. Further studies are warranted to clarify whether serum FGF-23 levels may be considered in predicting the risk of AF. Systematic Review Registration: http:www.york.ac.uk/inst/crd , identifier CRD42020182226." @default.
- W4289731333 created "2022-08-04" @default.
- W4289731333 creator A5005555710 @default.
- W4289731333 creator A5017947172 @default.
- W4289731333 creator A5031276674 @default.
- W4289731333 creator A5069013621 @default.
- W4289731333 creator A5069759127 @default.
- W4289731333 creator A5071349641 @default.
- W4289731333 creator A5076409244 @default.
- W4289731333 creator A5078613285 @default.
- W4289731333 date "2022-08-04" @default.
- W4289731333 modified "2023-10-18" @default.
- W4289731333 title "Relationship between serum growth differentiation factor 15, fibroblast growth factor-23 and risk of atrial fibrillation: A systematic review and meta-analysis" @default.
- W4289731333 cites W1534181333 @default.
- W4289731333 cites W1977183704 @default.
- W4289731333 cites W1999372562 @default.
- W4289731333 cites W2002312823 @default.
- W4289731333 cites W2027560922 @default.
- W4289731333 cites W2057798151 @default.
- W4289731333 cites W2066588520 @default.
- W4289731333 cites W2077838200 @default.
- W4289731333 cites W2091263837 @default.
- W4289731333 cites W2094925577 @default.
- W4289731333 cites W2101979840 @default.
- W4289731333 cites W2107454827 @default.
- W4289731333 cites W2114238925 @default.
- W4289731333 cites W2122584551 @default.
- W4289731333 cites W2132410244 @default.
- W4289731333 cites W2135806783 @default.
- W4289731333 cites W2145179900 @default.
- W4289731333 cites W2170892587 @default.
- W4289731333 cites W2277364556 @default.
- W4289731333 cites W2328630984 @default.
- W4289731333 cites W2332141348 @default.
- W4289731333 cites W2366508669 @default.
- W4289731333 cites W2470464816 @default.
- W4289731333 cites W2493079951 @default.
- W4289731333 cites W2506083433 @default.
- W4289731333 cites W2545266774 @default.
- W4289731333 cites W2546533026 @default.
- W4289731333 cites W2615881321 @default.
- W4289731333 cites W2617318893 @default.
- W4289731333 cites W2763370674 @default.
- W4289731333 cites W2765517876 @default.
- W4289731333 cites W2765549411 @default.
- W4289731333 cites W2771935284 @default.
- W4289731333 cites W2790294891 @default.
- W4289731333 cites W2807253610 @default.
- W4289731333 cites W2886002784 @default.
- W4289731333 cites W2888008746 @default.
- W4289731333 cites W2897220320 @default.
- W4289731333 cites W2900136549 @default.
- W4289731333 cites W2900449136 @default.
- W4289731333 cites W2905736690 @default.
- W4289731333 cites W2919253684 @default.
- W4289731333 cites W2953741209 @default.
- W4289731333 cites W2964593988 @default.
- W4289731333 cites W2984646011 @default.
- W4289731333 cites W2996552247 @default.
- W4289731333 cites W3011608774 @default.
- W4289731333 cites W3036116092 @default.
- W4289731333 cites W3044142829 @default.
- W4289731333 cites W3047375053 @default.
- W4289731333 cites W3080158097 @default.
- W4289731333 cites W3080708081 @default.
- W4289731333 cites W3082188176 @default.
- W4289731333 cites W3088385564 @default.
- W4289731333 cites W3091892146 @default.
- W4289731333 cites W3104079217 @default.
- W4289731333 cites W3135037521 @default.
- W4289731333 cites W3137668313 @default.
- W4289731333 cites W3153214255 @default.
- W4289731333 cites W4200456592 @default.
- W4289731333 cites W4200495872 @default.
- W4289731333 cites W42379819 @default.
- W4289731333 cites W3119138850 @default.
- W4289731333 doi "https://doi.org/10.3389/fcvm.2022.899667" @default.
- W4289731333 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35990956" @default.
- W4289731333 hasPublicationYear "2022" @default.
- W4289731333 type Work @default.
- W4289731333 citedByCount "3" @default.
- W4289731333 countsByYear W42897313332023 @default.
- W4289731333 crossrefType "journal-article" @default.
- W4289731333 hasAuthorship W4289731333A5005555710 @default.
- W4289731333 hasAuthorship W4289731333A5017947172 @default.
- W4289731333 hasAuthorship W4289731333A5031276674 @default.
- W4289731333 hasAuthorship W4289731333A5069013621 @default.
- W4289731333 hasAuthorship W4289731333A5069759127 @default.
- W4289731333 hasAuthorship W4289731333A5071349641 @default.
- W4289731333 hasAuthorship W4289731333A5076409244 @default.
- W4289731333 hasAuthorship W4289731333A5078613285 @default.
- W4289731333 hasBestOaLocation W42897313331 @default.
- W4289731333 hasConcept C120665830 @default.
- W4289731333 hasConcept C121332964 @default.
- W4289731333 hasConcept C126322002 @default.
- W4289731333 hasConcept C136935669 @default.
- W4289731333 hasConcept C2776478404 @default.
- W4289731333 hasConcept C2779161974 @default.
- W4289731333 hasConcept C44249647 @default.
- W4289731333 hasConcept C50440223 @default.