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- W4289732095 abstract "Gerstmann-Sträussler-Scheinker disease (GSS) is an autosomal dominant prion disease caused by a mutation in the prion protein gene (PRNP). The Pro→Leu mutation at codon 102 of PRNP (P102L) is the most common mutation associated with GSS (GSS-P102L), and patients commonly develop progressive cerebellar ataxia and dementia [1]. GSS is pathologically characterized by amyloid plaques consisting of prion protein (PrP) that are primarily observed in the cerebellum and cerebral cortex, astrocytosis, and spongiform degeneration [1,2]." @default.
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- W4289732095 date "2022-10-01" @default.
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- W4289732095 title "18F-THK5351 positron emission tomography imaging for Gerstmann-Sträussler-Scheinker disease" @default.
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- W4289732095 doi "https://doi.org/10.1016/j.jns.2022.120379" @default.
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