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- W4289732322 abstract "Deoxynivalenol (DON) is the most common mycotoxin contaminant of cereal-based food and animal feed. The toxicity of DON is very low compared to that of other toxins; however, the most prominent signs of DON exposure include inappetence and body weight loss, which causes considerable economic losses in the livestock industry. This review summarizes critical studies on biological DON mycotoxin mitigation strategies and the respective in vitro and in vivo intestinal effects. Focus areas include growth performance, gut health in terms of intestinal histomorphology, epithelial barrier functions, the intestinal immune system and microflora, and short-chain fatty acid production in the intestines. In addition, DON detoxification and modulation of these parameters, through biological supplements, are discussed. Biological detoxification of DON using microorganisms can attenuate DON toxicity by modulating gut microbiota and improving gut health with or without influencing the growth performance of pigs. However, the use of microorganisms as feed additives to livestock for mycotoxins detoxification needs more research before commercial use." @default.
- W4289732322 created "2022-08-04" @default.
- W4289732322 creator A5001959266 @default.
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- W4289732322 creator A5046341900 @default.
- W4289732322 creator A5048935439 @default.
- W4289732322 creator A5063098262 @default.
- W4289732322 date "2022-07-01" @default.
- W4289732322 modified "2023-09-30" @default.
- W4289732322 title "Protective effects of biological feed additives on gut microbiota and the health of pigs exposed to deoxynivalenol: a review" @default.
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- W4289732322 doi "https://doi.org/10.5187/jast.2022.e40" @default.
- W4289732322 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35969702" @default.
- W4289732322 hasPublicationYear "2022" @default.
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