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- W4289755059 startingPage "F435" @default.
- W4289755059 abstract "Chronic kidney disease (CKD) is a major unmet medical need with no effective treatment. Current findings demonstrate that hepatic and proximal tubule angiotensinogen have distinct roles in tubular and glomerular injury, fibrogenesis, and renal dysfunction during CKD development. As renin-angiotensin system components, including angiotensinogen, are important targets for treating CKD in the clinic, the results from our study may be applied to developing better tissue-targeted treatment strategies for CKD and other fibroproliferative diseases." @default.
- W4289755059 created "2022-08-04" @default.
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- W4289755059 date "2022-10-01" @default.
- W4289755059 modified "2023-10-03" @default.
- W4289755059 title "Hepatic and proximal tubule angiotensinogen play distinct roles in kidney dysfunction, glomerular and tubular injury, and fibrosis progression" @default.
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- W4289755059 doi "https://doi.org/10.1152/ajprenal.00029.2022" @default.
- W4289755059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35924445" @default.
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