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• W4289756522 abstract "During the past decade the view of Parkinson's disease (PD) as a motor disorder has changed significantly and currently it is recognized as a multisystem disorder with diverse non-motor symptoms (NMS).The present study aimed to evaluate and characterize the NMS and study their impact on quality of life (QoL) in a PD patient cohort.This was a cross-sectional study where 92 PD patients fulfilling the UK Parkinson's disease society brain bank criteria were enrolled from a movement disorder clinic. All patients were evaluated using unified Parkinson's disease rating scale, non-motor symptoms scale (NMSS) for the non-motor symptoms, and Parkinson's disease questionnaire-39 (PDQ-39) for the QoL. The impact of NMS on QoL was assessed statistically.A total of 92 patients were enrolled with a mean age of 55.40 ± 7.37 years, mean age of onset of disease 51.62 ± 6.38 years, and mean disease duration of 3.78 ± 1.54 years. Type of disease was akinetic rigid variant in 29.3% (n = 27), tremor predominant type in 36.9%(n = 34), and mixed type in 33.6% (n = 31). Mean Hoehn and Yahr stage was 2.12 ± 0.54. In the NMSS, most common symptom was sleep and fatigue (83%), followed by urinary tract symptoms (63%), mood and cognition (51%), cardiovascular symptoms and falls (43%), gastrointestinal tract symptoms (38%), and sexual function (33%). Univariate analyses showed that all NMS domains had a significant correlation with PDQ-39 with P < 001.Our study shows that NMS in PDare fairly common and significantly impact the QoL." @default.
• W4289756522 created "2022-08-04" @default.
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• W4289756522 date "2022-01-01" @default.
• W4289756522 modified "2023-09-26" @default.
• W4289756522 title "Assessment of non-motor symptoms of Parkinson's disease and their impact on the quality of life: An observatiobnal study" @default.
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• W4289756522 doi "https://doi.org/10.4103/aian.aian_647_21" @default.
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