FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289778755> ?p ?o ?g. }

• W4289778755 endingPage "107438" @default.
• W4289778755 startingPage "107438" @default.
• W4289778755 abstract "Lead exposure remains highly prevalent worldwide despite decades of research highlighting its link to numerous adverse health outcomes. In addition to well-documented effects on cognition, there is growing evidence of an association with antisocial behavior, including aggression, conduct problems, and crime. An updated systematic review on this topic, incorporating study evaluation and a developmental perspective on the outcome, can advance the state of the science on lead and inform global policy interventions to reduce exposure.We aim to evaluate the link between lead exposure and antisocial behavior. This association will be investigated via a systematic review of human epidemiological and experimental nonhuman mammalian studies.The systematic review protocol presented in this publication is informed by recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER) and follows the study evaluation approach put forth by the U.S. EPA Integrated Risk Information System (IRIS) program.We will search the following electronic databases for relevant literature: PubMed, BIOSIS and Web of Science. Search results will be stored in EPA's Health and Environmental Research Online (HERO) database.Eligible human epidemiological studies will include those evaluating any population exposed to lead at any lifestage via ingestion or inhalation exposure and considering an outcome of antisocial behavior based on any of the following criteria: psychiatric diagnoses (e.g., oppositional defiant disorder (ODD), conduct disorder (CD), disruptive behavior disorders (DBD)); violation of social norms (e.g., delinquency, criminality); and aggression. Eligible experimental animal studies will include those evaluating nonhuman mammalian studies exposed to lead via ingestion, inhalation, or injection exposure during any lifestage. The following outcomes will be considered relevant: aggression; antisocial behavior; and altered fear, anxiety, and stress response.Screening will be conducted with assistance from an artificial intelligence application. Two independent reviewers for each data stream (human, animal) will screen studies with highest predicted relevance against pre-specified inclusion criteria at the title/abstract and full-text level. Study evaluation will be conducted using methods adapted from the U.S. EPA IRIS program. After data extraction, we will conduct a narrative review and quantitative meta-analysis on the human epidemiological studies as well as a narrative review of the experimental animal studies. We will evaluate the strength of each evidence stream separately and then will develop a summary evidence integration statement based on inference across evidence streams." @default.
• W4289778755 created "2022-08-04" @default.
• W4289778755 creator A5006303273 @default.
• W4289778755 creator A5011876301 @default.
• W4289778755 creator A5019699057 @default.
• W4289778755 creator A5020684769 @default.
• W4289778755 creator A5031120167 @default.
• W4289778755 creator A5051771078 @default.
• W4289778755 creator A5058385754 @default.
• W4289778755 creator A5060925295 @default.
• W4289778755 creator A5061205098 @default.
• W4289778755 creator A5078987114 @default.
• W4289778755 creator A5088973907 @default.
• W4289778755 date "2022-10-01" @default.
• W4289778755 modified "2023-10-14" @default.
• W4289778755 title "Lead exposure and antisocial behavior: A systematic review protocol" @default.
• W4289778755 cites W1519020267 @default.
• W4289778755 cites W1788296118 @default.
• W4289778755 cites W1924959571 @default.
• W4289778755 cites W1967597602 @default.
• W4289778755 cites W1969040051 @default.
• W4289778755 cites W1969408194 @default.
• W4289778755 cites W1976123306 @default.
• W4289778755 cites W1982601920 @default.
• W4289778755 cites W1983774090 @default.
• W4289778755 cites W1983923566 @default.
• W4289778755 cites W1987234822 @default.
• W4289778755 cites W1987298274 @default.
• W4289778755 cites W2004124667 @default.
• W4289778755 cites W2009502998 @default.
• W4289778755 cites W2009964102 @default.
• W4289778755 cites W2012107441 @default.
• W4289778755 cites W2025292518 @default.
• W4289778755 cites W2027284940 @default.
• W4289778755 cites W2033585778 @default.
• W4289778755 cites W2044323528 @default.
• W4289778755 cites W2044624532 @default.
• W4289778755 cites W2047933675 @default.
• W4289778755 cites W2048733066 @default.
• W4289778755 cites W2049868313 @default.
• W4289778755 cites W2053784182 @default.
• W4289778755 cites W2056694377 @default.
• W4289778755 cites W2057236586 @default.
• W4289778755 cites W2059588968 @default.
• W4289778755 cites W2063148725 @default.
• W4289778755 cites W2068713417 @default.
• W4289778755 cites W2068843023 @default.
• W4289778755 cites W2069319842 @default.
• W4289778755 cites W2069775747 @default.
• W4289778755 cites W2069952668 @default.
• W4289778755 cites W2071442432 @default.
• W4289778755 cites W2075459058 @default.
• W4289778755 cites W2108298390 @default.
• W4289778755 cites W2108307535 @default.
• W4289778755 cites W2108330139 @default.
• W4289778755 cites W2116428678 @default.
• W4289778755 cites W2119515241 @default.
• W4289778755 cites W2119559591 @default.
• W4289778755 cites W2125192512 @default.
• W4289778755 cites W2126489758 @default.
• W4289778755 cites W2136299183 @default.
• W4289778755 cites W2140131912 @default.
• W4289778755 cites W2141604349 @default.
• W4289778755 cites W2152288875 @default.
• W4289778755 cites W2153501396 @default.
• W4289778755 cites W2159218209 @default.
• W4289778755 cites W2160255310 @default.
• W4289778755 cites W2161374186 @default.
• W4289778755 cites W2162020219 @default.
• W4289778755 cites W2162542540 @default.
• W4289778755 cites W2167698180 @default.
• W4289778755 cites W2167894329 @default.
• W4289778755 cites W2213487080 @default.
• W4289778755 cites W2228338508 @default.
• W4289778755 cites W2274562574 @default.
• W4289778755 cites W2325927640 @default.
• W4289778755 cites W2343135765 @default.
• W4289778755 cites W2401236284 @default.
• W4289778755 cites W2460736156 @default.
• W4289778755 cites W2539502410 @default.
• W4289778755 cites W2546493633 @default.
• W4289778755 cites W2572804338 @default.
• W4289778755 cites W2577943524 @default.
• W4289778755 cites W2589976179 @default.
• W4289778755 cites W2596968510 @default.
• W4289778755 cites W2612638299 @default.
• W4289778755 cites W2727282714 @default.
• W4289778755 cites W2737468821 @default.
• W4289778755 cites W2765659980 @default.
• W4289778755 cites W2767732252 @default.
• W4289778755 cites W2775994343 @default.
• W4289778755 cites W2780961888 @default.
• W4289778755 cites W2903367641 @default.
• W4289778755 cites W2914686075 @default.
• W4289778755 cites W2919877591 @default.
• W4289778755 cites W2922623598 @default.
• W4289778755 cites W2947331878 @default.
• W4289778755 cites W2965922023 @default.

• next