FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4289856945> ?p ?o ?g. }

• W4289856945 endingPage "4543" @default.
• W4289856945 startingPage "4543" @default.
• W4289856945 abstract "Mid-regional proadrenomedullin (MR-proADM) is a new biomarker of endothelial damage and its clinical use is increasing in sepsis and respiratory infections and recently in SARS-CoV-2 infection. We conducted a systematic review and meta-analysis to clarify the use of MR-proADM in severe COVID-19 disease. After Pubmed, Embase, and Scopus search, registries, and gray literature, deduplication, and selection of full-texts, we found 21 studies addressing the use of proadrenomedullin in COVID-19. All the studies were published between 2020 and 2022 from European countries. A total of 9 studies enrolled Intensive Care Unit (ICU) patients, 4 were conducted in the Emergency Department, and 8 had mixed populations. Regarding the ICU critically ill patients, 4 studies evaluating survival as primary outcome were available, of which 3 reported completed data. Combining the selected studies in a meta-analysis, a total of 252 patients were enrolled; of these, 182 were survivors and 70 were non-survivors. At the admission to the ICU, the average MR-proADM level in survivor patients was 1.01 versus 1.64 in non-survivor patients. The mean differences of MR-proADM values in survivors vs. non-survivors was −0.96 (95% CI from −1.26, to −0.65). Test for overall effect: Z = 6.19 (p < 0.00001) and heterogeneity was I2 = 0%. MR-proADM ICU admission levels seem to predict mortality among the critical COVID-19 population. Further, prospective studies, focused on critically ill patients and investigating a reliable MR-proADM cut-off, are needed to provide adequate guidance to its use in severe COVID-19." @default.
• W4289856945 created "2022-08-05" @default.
• W4289856945 creator A5002143975 @default.
• W4289856945 creator A5015238111 @default.
• W4289856945 creator A5034940912 @default.
• W4289856945 creator A5040358169 @default.
• W4289856945 creator A5043266994 @default.
• W4289856945 creator A5059741950 @default.
• W4289856945 creator A5062757956 @default.
• W4289856945 creator A5069948590 @default.
• W4289856945 creator A5088611784 @default.
• W4289856945 date "2022-08-04" @default.
• W4289856945 modified "2023-09-26" @default.
• W4289856945 title "Proadrenomedullin in the Management of COVID-19 Critically Ill Patients in Intensive Care Unit: A Systematic Review and Meta-Analysis of Evidence and Uncertainties in Existing Literature" @default.
• W4289856945 cites W1534181333 @default.
• W4289856945 cites W2004689339 @default.
• W4289856945 cites W2051810155 @default.
• W4289856945 cites W2531269403 @default.
• W4289856945 cites W2797283758 @default.
• W4289856945 cites W2888823417 @default.
• W4289856945 cites W2919615971 @default.
• W4289856945 cites W2970684805 @default.
• W4289856945 cites W2975327746 @default.
• W4289856945 cites W2978795816 @default.
• W4289856945 cites W3017125154 @default.
• W4289856945 cites W3042141873 @default.
• W4289856945 cites W3106124442 @default.
• W4289856945 cites W3113676987 @default.
• W4289856945 cites W3115660609 @default.
• W4289856945 cites W3116534174 @default.
• W4289856945 cites W3118942590 @default.
• W4289856945 cites W3125580417 @default.
• W4289856945 cites W3129737158 @default.
• W4289856945 cites W3133946785 @default.
• W4289856945 cites W3139022221 @default.
• W4289856945 cites W3139137489 @default.
• W4289856945 cites W3153160671 @default.
• W4289856945 cites W3157355755 @default.
• W4289856945 cites W3159451078 @default.
• W4289856945 cites W3185110418 @default.
• W4289856945 cites W3196461144 @default.
• W4289856945 cites W3197659015 @default.
• W4289856945 cites W3201442945 @default.
• W4289856945 cites W3202298400 @default.
• W4289856945 cites W3203725826 @default.
• W4289856945 cites W3211009331 @default.
• W4289856945 cites W3217380337 @default.
• W4289856945 cites W4200272776 @default.
• W4289856945 cites W4200564185 @default.
• W4289856945 cites W4206419645 @default.
• W4289856945 cites W4210733948 @default.
• W4289856945 cites W4220809715 @default.
• W4289856945 doi "https://doi.org/10.3390/jcm11154543" @default.
• W4289856945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35956159" @default.
• W4289856945 hasPublicationYear "2022" @default.
• W4289856945 type Work @default.
• W4289856945 citedByCount "4" @default.
• W4289856945 countsByYear W42898569452022 @default.
• W4289856945 countsByYear W42898569452023 @default.
• W4289856945 crossrefType "journal-article" @default.
• W4289856945 hasAuthorship W4289856945A5002143975 @default.
• W4289856945 hasAuthorship W4289856945A5015238111 @default.
• W4289856945 hasAuthorship W4289856945A5034940912 @default.
• W4289856945 hasAuthorship W4289856945A5040358169 @default.
• W4289856945 hasAuthorship W4289856945A5043266994 @default.
• W4289856945 hasAuthorship W4289856945A5059741950 @default.
• W4289856945 hasAuthorship W4289856945A5062757956 @default.
• W4289856945 hasAuthorship W4289856945A5069948590 @default.
• W4289856945 hasAuthorship W4289856945A5088611784 @default.
• W4289856945 hasBestOaLocation W42898569451 @default.
• W4289856945 hasConcept C118552586 @default.
• W4289856945 hasConcept C126322002 @default.
• W4289856945 hasConcept C17744445 @default.
• W4289856945 hasConcept C177713679 @default.
• W4289856945 hasConcept C194828623 @default.
• W4289856945 hasConcept C199539241 @default.
• W4289856945 hasConcept C2776376669 @default.
• W4289856945 hasConcept C2778384902 @default.
• W4289856945 hasConcept C2779134260 @default.
• W4289856945 hasConcept C2779473830 @default.
• W4289856945 hasConcept C2780724011 @default.
• W4289856945 hasConcept C2908647359 @default.
• W4289856945 hasConcept C2987404301 @default.
• W4289856945 hasConcept C2991859549 @default.
• W4289856945 hasConcept C3008058167 @default.
• W4289856945 hasConcept C524204448 @default.
• W4289856945 hasConcept C71924100 @default.
• W4289856945 hasConcept C95190672 @default.
• W4289856945 hasConcept C99454951 @default.
• W4289856945 hasConceptScore W4289856945C118552586 @default.
• W4289856945 hasConceptScore W4289856945C126322002 @default.
• W4289856945 hasConceptScore W4289856945C17744445 @default.
• W4289856945 hasConceptScore W4289856945C177713679 @default.
• W4289856945 hasConceptScore W4289856945C194828623 @default.
• W4289856945 hasConceptScore W4289856945C199539241 @default.
• W4289856945 hasConceptScore W4289856945C2776376669 @default.
• W4289856945 hasConceptScore W4289856945C2778384902 @default.
• W4289856945 hasConceptScore W4289856945C2779134260 @default.

• next