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- W4290052404 endingPage "1099" @default.
- W4290052404 startingPage "1091" @default.
- W4290052404 abstract "Phosphate plays a critical and diverse role in human physiology. In addition to its importance in skeletal mineralization, it is essential for energy homeostasis, enzyme function, and cell membrane integrity. These diverse functions of phosphate provide an explanation for the range of symptoms and clinical manifestations observed in patients with both acute and chronic causes of hypophosphatemia. Normal phosphate homeostasis involves several major systems, including the gastrointestinal tract, bones, and kidneys. Phosphate balance is maintained directly and indirectly by 1α,25-dihydroxyvitamin D3, parathyroid hormone, and the osteocyte-derived phosphatonin fibroblast growth factor 23. This review discusses normal phosphate homeostasis, the clinical manifestations and causes of hypophosphatemia, and an approach to establish a diagnosis and appropriate management." @default.
- W4290052404 created "2022-08-06" @default.
- W4290052404 creator A5079731206 @default.
- W4290052404 date "2022-10-01" @default.
- W4290052404 modified "2023-10-03" @default.
- W4290052404 title "Hypophosphatemia: A Practical Guide to Evaluation and Management" @default.
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- W4290052404 doi "https://doi.org/10.1016/j.eprac.2022.07.005" @default.
- W4290052404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35940468" @default.
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