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- W4290102144 abstract "Malaria is a gruesome disease caused by Plasmodium parasites and poses a major medical risk in large parts of the world. The development of new, affordable antimalarial drugs is of vital importance as there are increasing reports of resistance to currently available therapeutics. Therefore, there is an urgent need for antimalarials with improved properties as compared to older therapies. The aminoquinoline pharmacophore has been shown to possess a large array of diverse pharmacological activities, the most important being antimalarial. This book chapter is mainly focused on the history and the recent advancements in the synthetic approach of 8-aminoquinoline and 4-aminoquinoline classes of antimalarials." @default.
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- W4290102144 date "2022-08-05" @default.
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- W4290102144 title "Discovery and Trends of 8‐Aminoquinoline and 4‐Aminoquinoline Classes of Antimalarials" @default.
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- W4290102144 doi "https://doi.org/10.1002/9783527830589.ch11" @default.
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