Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290157568> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4290157568 endingPage "5" @default.
- W4290157568 startingPage "450" @default.
- W4290157568 abstract "The natural history of lymphocytic lymphomata is such that anatomical generalization of disease is usually present at the time of diagnosis. Tumour infiltration of extralymphatic sites such as the liver and bone marrow is identifiable with particular frequency in those cases presenting with lymph node manifestations of disease. Even in the absence of detectable extralymphatic dissemination, the lymphatic involvement is often sufficiently diffuse to mitigate against extensive lymph node irradiation à la Hodgkin's disease as appropriate or technically feasible form of treatment. Rather, systemic treatment must be recognized as imperative for the majority of newly diagnosed patients and we have investigated systemic radiotherapy as an alternative to chemotherapy during the past decade. Our experience with 57 consecutive patients with lymphocytic lymphoma has been reviewed. Total body irradiation (TBI) has been found to yield high remission rates despite a lack of serious toxicity or constitutional reactions. Rigorous diagnostic staging was not employed but despite the advanced stage of disease which was clinically obvious in most cases, survival rates have been strikingly high. Actuarially calculated 5-year survival rates for the well differentiated (diffuse and nodular combined), nodular poorly differentiated and diffuse poorly differentiated subtypes are 85%, 69% and 51% respectively. Furthermore, initial management with radio-therapy as described has not negated with effective use of subsequent chemotherapy when selectively required." @default.
- W4290157568 created "2022-08-07" @default.
- W4290157568 creator A5081350762 @default.
- W4290157568 date "1975-03-01" @default.
- W4290157568 modified "2023-09-29" @default.
- W4290157568 title "Management of generalized malignant lymphomata with systemic radiotherapy." @default.
- W4290157568 cites W1429008849 @default.
- W4290157568 cites W158134887 @default.
- W4290157568 cites W181443799 @default.
- W4290157568 cites W1990923516 @default.
- W4290157568 cites W2005565096 @default.
- W4290157568 cites W2032819230 @default.
- W4290157568 cites W2050941456 @default.
- W4290157568 cites W2172187882 @default.
- W4290157568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1242362" @default.
- W4290157568 hasPublicationYear "1975" @default.
- W4290157568 type Work @default.
- W4290157568 citedByCount "4" @default.
- W4290157568 countsByYear W42901575682021 @default.
- W4290157568 crossrefType "journal-article" @default.
- W4290157568 hasAuthorship W4290157568A5081350762 @default.
- W4290157568 hasConcept C121608353 @default.
- W4290157568 hasConcept C126322002 @default.
- W4290157568 hasConcept C126838900 @default.
- W4290157568 hasConcept C142724271 @default.
- W4290157568 hasConcept C143998085 @default.
- W4290157568 hasConcept C163276114 @default.
- W4290157568 hasConcept C181152851 @default.
- W4290157568 hasConcept C185926286 @default.
- W4290157568 hasConcept C2776694085 @default.
- W4290157568 hasConcept C2779134260 @default.
- W4290157568 hasConcept C2779338263 @default.
- W4290157568 hasConcept C2780007613 @default.
- W4290157568 hasConcept C2780849966 @default.
- W4290157568 hasConcept C509974204 @default.
- W4290157568 hasConcept C530470458 @default.
- W4290157568 hasConcept C71924100 @default.
- W4290157568 hasConceptScore W4290157568C121608353 @default.
- W4290157568 hasConceptScore W4290157568C126322002 @default.
- W4290157568 hasConceptScore W4290157568C126838900 @default.
- W4290157568 hasConceptScore W4290157568C142724271 @default.
- W4290157568 hasConceptScore W4290157568C143998085 @default.
- W4290157568 hasConceptScore W4290157568C163276114 @default.
- W4290157568 hasConceptScore W4290157568C181152851 @default.
- W4290157568 hasConceptScore W4290157568C185926286 @default.
- W4290157568 hasConceptScore W4290157568C2776694085 @default.
- W4290157568 hasConceptScore W4290157568C2779134260 @default.
- W4290157568 hasConceptScore W4290157568C2779338263 @default.
- W4290157568 hasConceptScore W4290157568C2780007613 @default.
- W4290157568 hasConceptScore W4290157568C2780849966 @default.
- W4290157568 hasConceptScore W4290157568C509974204 @default.
- W4290157568 hasConceptScore W4290157568C530470458 @default.
- W4290157568 hasConceptScore W4290157568C71924100 @default.
- W4290157568 hasLocation W42901575681 @default.
- W4290157568 hasOpenAccess W4290157568 @default.
- W4290157568 hasPrimaryLocation W42901575681 @default.
- W4290157568 hasRelatedWork W132604569 @default.
- W4290157568 hasRelatedWork W1995684673 @default.
- W4290157568 hasRelatedWork W2063122185 @default.
- W4290157568 hasRelatedWork W2125927297 @default.
- W4290157568 hasRelatedWork W2171422777 @default.
- W4290157568 hasRelatedWork W2315025365 @default.
- W4290157568 hasRelatedWork W2335585087 @default.
- W4290157568 hasRelatedWork W2413089076 @default.
- W4290157568 hasRelatedWork W2416632858 @default.
- W4290157568 hasRelatedWork W2948058885 @default.
- W4290157568 hasVolume "2" @default.
- W4290157568 isParatext "false" @default.
- W4290157568 isRetracted "false" @default.
- W4290157568 workType "article" @default.