Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290206069> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4290206069 endingPage "51" @default.
- W4290206069 startingPage "47" @default.
- W4290206069 abstract "We have determined the fetal expression of V gamma 3, delta and beta TcRs in mice transgenic for the V gamma 1.1J4C gamma 4 TcR chain. The first wave thymocytes appearing at day 14 and disappearing by day 17 in normal mice was absent from the transgenic mice. However, both mice had an almost identical number of gamma delta-bearing thymocytes throughout gestation. Therefore, it is most likely that the V gamma 3J gamma 1C gamma 1 chain was replaced in the transgenic mice by the V gamma 1.1J gamma 4C gamma 4 transgene. The appearance, although slightly earlier for the transgenic mice, of alpha beta-bearing thymocytes was also very similar between transgenic and control mice during gestation. These data suggest that whatever the role of the first wave thymocytes expressing V3-V delta 1 TcRs is, it most likely is not required for the rearrangement, expression and maturation of the alpha beta TcR repertoire. We are currently analyzing a series of gamma delta transgenic mice to determine whether other restricted populations of gamma delta-bearing T cells are involved in specific aspects of immune development or function." @default.
- W4290206069 created "2022-08-07" @default.
- W4290206069 creator A5016727533 @default.
- W4290206069 creator A5067084108 @default.
- W4290206069 creator A5076485899 @default.
- W4290206069 date "1991-01-01" @default.
- W4290206069 modified "2023-09-27" @default.
- W4290206069 title "First wave fetal thymocytes expressing V3J gamma 1C gamma 1-V delta 1J delta 2C delta T cell receptors are not required for alpha beta T cell receptor rearrangement and expression." @default.
- W4290206069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1659147" @default.
- W4290206069 hasPublicationYear "1991" @default.
- W4290206069 type Work @default.
- W4290206069 citedByCount "0" @default.
- W4290206069 crossrefType "journal-article" @default.
- W4290206069 hasAuthorship W4290206069A5016727533 @default.
- W4290206069 hasAuthorship W4290206069A5067084108 @default.
- W4290206069 hasAuthorship W4290206069A5076485899 @default.
- W4290206069 hasConcept C102230213 @default.
- W4290206069 hasConcept C104317684 @default.
- W4290206069 hasConcept C121332964 @default.
- W4290206069 hasConcept C1276947 @default.
- W4290206069 hasConcept C141035611 @default.
- W4290206069 hasConcept C153911025 @default.
- W4290206069 hasConcept C159110408 @default.
- W4290206069 hasConcept C170493617 @default.
- W4290206069 hasConcept C19317047 @default.
- W4290206069 hasConcept C199360897 @default.
- W4290206069 hasConcept C203014093 @default.
- W4290206069 hasConcept C2775944032 @default.
- W4290206069 hasConcept C2776090121 @default.
- W4290206069 hasConcept C2776174256 @default.
- W4290206069 hasConcept C2778954852 @default.
- W4290206069 hasConcept C2778993397 @default.
- W4290206069 hasConcept C41008148 @default.
- W4290206069 hasConcept C49453240 @default.
- W4290206069 hasConcept C5072461 @default.
- W4290206069 hasConcept C54355233 @default.
- W4290206069 hasConcept C64943373 @default.
- W4290206069 hasConcept C71924100 @default.
- W4290206069 hasConcept C86803240 @default.
- W4290206069 hasConcept C8891405 @default.
- W4290206069 hasConceptScore W4290206069C102230213 @default.
- W4290206069 hasConceptScore W4290206069C104317684 @default.
- W4290206069 hasConceptScore W4290206069C121332964 @default.
- W4290206069 hasConceptScore W4290206069C1276947 @default.
- W4290206069 hasConceptScore W4290206069C141035611 @default.
- W4290206069 hasConceptScore W4290206069C153911025 @default.
- W4290206069 hasConceptScore W4290206069C159110408 @default.
- W4290206069 hasConceptScore W4290206069C170493617 @default.
- W4290206069 hasConceptScore W4290206069C19317047 @default.
- W4290206069 hasConceptScore W4290206069C199360897 @default.
- W4290206069 hasConceptScore W4290206069C203014093 @default.
- W4290206069 hasConceptScore W4290206069C2775944032 @default.
- W4290206069 hasConceptScore W4290206069C2776090121 @default.
- W4290206069 hasConceptScore W4290206069C2776174256 @default.
- W4290206069 hasConceptScore W4290206069C2778954852 @default.
- W4290206069 hasConceptScore W4290206069C2778993397 @default.
- W4290206069 hasConceptScore W4290206069C41008148 @default.
- W4290206069 hasConceptScore W4290206069C49453240 @default.
- W4290206069 hasConceptScore W4290206069C5072461 @default.
- W4290206069 hasConceptScore W4290206069C54355233 @default.
- W4290206069 hasConceptScore W4290206069C64943373 @default.
- W4290206069 hasConceptScore W4290206069C71924100 @default.
- W4290206069 hasConceptScore W4290206069C86803240 @default.
- W4290206069 hasConceptScore W4290206069C8891405 @default.
- W4290206069 hasLocation W42902060691 @default.
- W4290206069 hasOpenAccess W4290206069 @default.
- W4290206069 hasPrimaryLocation W42902060691 @default.
- W4290206069 hasRelatedWork W123468624 @default.
- W4290206069 hasRelatedWork W1583167254 @default.
- W4290206069 hasRelatedWork W2020488799 @default.
- W4290206069 hasRelatedWork W2035095149 @default.
- W4290206069 hasRelatedWork W2094470122 @default.
- W4290206069 hasRelatedWork W2118872774 @default.
- W4290206069 hasRelatedWork W2143755366 @default.
- W4290206069 hasRelatedWork W2410445305 @default.
- W4290206069 hasRelatedWork W2410780756 @default.
- W4290206069 hasRelatedWork W2417778353 @default.
- W4290206069 hasVolume "292" @default.
- W4290206069 isParatext "false" @default.
- W4290206069 isRetracted "false" @default.
- W4290206069 workType "article" @default.