Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290737323> ?p ?o ?g. }
- W4290737323 endingPage "8351" @default.
- W4290737323 startingPage "8329" @default.
- W4290737323 abstract "This study compares two types of bioresorptive cellulose, i.e., calcium-sodium salt of oxidized cellulose (OC) and sodium salt of carboxymethylcellulose (CMC). It investigates which type would be preferable as an implant material in terms of biocompatibility, biomechanical and biological properties, and also in terms of its behavior in combination with collagen fibrils (Col) in composite Col/OC or Col/CMC scaffolds. OC significantly supported the stiffness and elasticity of Col fibrils, whereas CMC significantly reduced these properties. OC also enabled a strong interaction with Col fibrils even in a moist environment, accompanied by a significant drop in elastic modulus. The addition of cellulose did not significantly influence scaffold porosity; however, changes in surface morphology and the lower swelling capacity of OC, with a degree of oxidation of its chains between 16 and 24%, supported the idea of improved cell-material interaction. The elasticity and the stiffness of Col/OC guided human adipose-derived stem cells (hADSCs) to significantly higher adhesion, proliferation, and metabolic activity. On the contrary, the Col/CMC provided only limited mechanical support for the cells and inhibited their attachment and proliferation, although without any signs of cytotoxicity. This phenomenon could be used for future control of the differentiation of hADSCs towards a desired phenotype to generate advanced tissue replacements using modern methods of tissue engineering. The oxidation of cellulose resulted in a firmer scaffolding material, as required in vascular or skin tissue engineering. CMC is suitable for moist wound healing, e.g. as a mucoadhesive gel, where cell adhesion is not desirable." @default.
- W4290737323 created "2022-08-09" @default.
- W4290737323 creator A5008126762 @default.
- W4290737323 creator A5021734725 @default.
- W4290737323 creator A5031800350 @default.
- W4290737323 creator A5034033315 @default.
- W4290737323 creator A5053410783 @default.
- W4290737323 creator A5057127331 @default.
- W4290737323 creator A5062687074 @default.
- W4290737323 creator A5071818411 @default.
- W4290737323 creator A5085338486 @default.
- W4290737323 creator A5089655445 @default.
- W4290737323 date "2022-08-09" @default.
- W4290737323 modified "2023-10-18" @default.
- W4290737323 title "Porous cellulose-collagen scaffolds for soft tissue regeneration: influence of cellulose derivatives on mechanical properties and compatibility with adipose-derived stem cells" @default.
- W4290737323 cites W1581527645 @default.
- W4290737323 cites W1586316048 @default.
- W4290737323 cites W1856525949 @default.
- W4290737323 cites W1970739085 @default.
- W4290737323 cites W1972229031 @default.
- W4290737323 cites W1974170815 @default.
- W4290737323 cites W1976608808 @default.
- W4290737323 cites W1979190963 @default.
- W4290737323 cites W1984180296 @default.
- W4290737323 cites W1991319278 @default.
- W4290737323 cites W1995509083 @default.
- W4290737323 cites W1999323056 @default.
- W4290737323 cites W2004784678 @default.
- W4290737323 cites W2005872694 @default.
- W4290737323 cites W2013265248 @default.
- W4290737323 cites W2014571830 @default.
- W4290737323 cites W2016241218 @default.
- W4290737323 cites W2020192436 @default.
- W4290737323 cites W2023897939 @default.
- W4290737323 cites W2024210081 @default.
- W4290737323 cites W2031431719 @default.
- W4290737323 cites W2032021220 @default.
- W4290737323 cites W2036224083 @default.
- W4290737323 cites W2049962163 @default.
- W4290737323 cites W2053268917 @default.
- W4290737323 cites W2053966728 @default.
- W4290737323 cites W2055230826 @default.
- W4290737323 cites W2071534524 @default.
- W4290737323 cites W2077823765 @default.
- W4290737323 cites W2079539415 @default.
- W4290737323 cites W2081958397 @default.
- W4290737323 cites W2083708858 @default.
- W4290737323 cites W2089081653 @default.
- W4290737323 cites W2091424226 @default.
- W4290737323 cites W2126284874 @default.
- W4290737323 cites W2129280755 @default.
- W4290737323 cites W2132953686 @default.
- W4290737323 cites W2140396888 @default.
- W4290737323 cites W2153320120 @default.
- W4290737323 cites W2159185781 @default.
- W4290737323 cites W2161162374 @default.
- W4290737323 cites W2167373002 @default.
- W4290737323 cites W2252957247 @default.
- W4290737323 cites W2265225559 @default.
- W4290737323 cites W2407223126 @default.
- W4290737323 cites W2417020181 @default.
- W4290737323 cites W2515033786 @default.
- W4290737323 cites W2560904168 @default.
- W4290737323 cites W2585885368 @default.
- W4290737323 cites W2617946223 @default.
- W4290737323 cites W2668397382 @default.
- W4290737323 cites W2753755559 @default.
- W4290737323 cites W2763304324 @default.
- W4290737323 cites W2777846529 @default.
- W4290737323 cites W2789316594 @default.
- W4290737323 cites W2789930460 @default.
- W4290737323 cites W2790547939 @default.
- W4290737323 cites W2883081942 @default.
- W4290737323 cites W2888881968 @default.
- W4290737323 cites W2895344817 @default.
- W4290737323 cites W2899253560 @default.
- W4290737323 cites W2904178020 @default.
- W4290737323 cites W2918000376 @default.
- W4290737323 cites W2921415885 @default.
- W4290737323 cites W2945690483 @default.
- W4290737323 cites W2952681866 @default.
- W4290737323 cites W2957928078 @default.
- W4290737323 cites W2959253429 @default.
- W4290737323 cites W2961090736 @default.
- W4290737323 cites W2971711430 @default.
- W4290737323 cites W3004878409 @default.
- W4290737323 cites W3008205335 @default.
- W4290737323 cites W3015414072 @default.
- W4290737323 cites W3026478671 @default.
- W4290737323 cites W3092386933 @default.
- W4290737323 cites W3092976341 @default.
- W4290737323 cites W3094482343 @default.
- W4290737323 cites W3096908175 @default.
- W4290737323 cites W3109917395 @default.
- W4290737323 cites W3129045694 @default.
- W4290737323 cites W3135810861 @default.
- W4290737323 cites W3145961192 @default.
- W4290737323 cites W3169818598 @default.