Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290793757> ?p ?o ?g. }
- W4290793757 endingPage "1036" @default.
- W4290793757 startingPage "1036" @default.
- W4290793757 abstract "Overall stroke incidence is falling in high-income countries, but data on time trends in incidence of young stroke (ie, stroke in individuals younger than 55 years) are conflicting. An age-specific divergence in incidence, with less favorable trends at younger vs older ages, might be a more consistent underlying finding across studies.To compare temporal trends in incidence of stroke at younger vs older ages in high-income countries.PubMed and EMBASE were searched from inception to February 2022. One additional population-based study (Oxford Vascular Study) was also included.Studies reporting age-specific stroke incidence in high-income countries at more than 1 time point.For all retrieved studies, 2 authors independently reviewed the full text against the inclusion criteria to establish their eligibility. Meta-analysis was performed with the inverse variance-weighted random-effects model. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guideline was followed.The main outcome was age-specific divergence (<55 vs ≥55 years) in temporal trends in stroke incidence (relative temporal rate ratio [RTTR]) in studies extending to at least 2000. RTTRs were calculated for each study and pooled by random-effects meta-analysis, with stratification by administrative vs prospective population-based methodology, sex, stroke subtype (ischemic vs intracerebral hemorrhage vs subarachnoid hemorrhage) and geographical region.Among 50 studies in 20 countries, 26 (13 prospective population-based and 13 administrative studies) reported data allowing calculation of the RTTR for stroke incidence at younger vs older ages across 2 or more periods, the latest extending beyond 2000. Reported trends in absolute incidence of young individuals with stroke were heterogeneous, but all studies showed a less favorable trend in incidence at younger vs older ages (pooled RTTR = 1.57 [95% CI, 1.42-1.74]). The overall RTTR was consistent by stroke subtype (ischemic, 1.62 [95% CI, 1.44-1.83]; intracerebral hemorrhage, 1.32 [95% CI, 0.91-1.92]; subarachnoid hemorrhage, 1.54 [95% CI, 1.00-2.35]); and by sex (men, 1.46 [95% CI, 1.34-1.60]; women, 1.41 [95% CI, 1.28-1.55]) but was greater in studies reporting trends solely after 2000 (1.51 [95% CI, 1.30-1.70]) vs solely before (1.18 [95% CI, 1.12-1.24]) and was highest in population-based studies in which the most recent reported period of ascertainment started after 2010 (1.87 [95% CI, 1.55-2.27]).Temporal trends in stroke incidence are diverging by age in high-income countries, with less favorable trends at younger vs older ages, highlighting the urgent need to better understand etiology and prevention of stroke at younger ages." @default.
- W4290793757 created "2022-08-09" @default.
- W4290793757 creator A5015842090 @default.
- W4290793757 creator A5018531683 @default.
- W4290793757 creator A5024332094 @default.
- W4290793757 date "2022-10-01" @default.
- W4290793757 modified "2023-10-17" @default.
- W4290793757 title "Diverging Temporal Trends in Stroke Incidence in Younger vs Older People" @default.
- W4290793757 cites W1759525783 @default.
- W4290793757 cites W1854438522 @default.
- W4290793757 cites W1985523900 @default.
- W4290793757 cites W1987751736 @default.
- W4290793757 cites W1991528246 @default.
- W4290793757 cites W2004392115 @default.
- W4290793757 cites W2006768708 @default.
- W4290793757 cites W2007918917 @default.
- W4290793757 cites W2008648973 @default.
- W4290793757 cites W2019441496 @default.
- W4290793757 cites W2026513192 @default.
- W4290793757 cites W2026923449 @default.
- W4290793757 cites W2032044549 @default.
- W4290793757 cites W2046161028 @default.
- W4290793757 cites W2047118931 @default.
- W4290793757 cites W2053559585 @default.
- W4290793757 cites W2055943130 @default.
- W4290793757 cites W2056370836 @default.
- W4290793757 cites W2057074643 @default.
- W4290793757 cites W2061976067 @default.
- W4290793757 cites W2065054039 @default.
- W4290793757 cites W2067727468 @default.
- W4290793757 cites W2077373745 @default.
- W4290793757 cites W2079570361 @default.
- W4290793757 cites W2083600673 @default.
- W4290793757 cites W2086342651 @default.
- W4290793757 cites W2087731895 @default.
- W4290793757 cites W2089709124 @default.
- W4290793757 cites W2093335988 @default.
- W4290793757 cites W2100115466 @default.
- W4290793757 cites W2100287642 @default.
- W4290793757 cites W2101774513 @default.
- W4290793757 cites W2104201135 @default.
- W4290793757 cites W2106480309 @default.
- W4290793757 cites W2109705034 @default.
- W4290793757 cites W2109821993 @default.
- W4290793757 cites W2110309960 @default.
- W4290793757 cites W2113333920 @default.
- W4290793757 cites W2121894721 @default.
- W4290793757 cites W2123430282 @default.
- W4290793757 cites W2136587148 @default.
- W4290793757 cites W2143556886 @default.
- W4290793757 cites W2147745911 @default.
- W4290793757 cites W2154786578 @default.
- W4290793757 cites W2156265933 @default.
- W4290793757 cites W2159894082 @default.
- W4290793757 cites W2163570199 @default.
- W4290793757 cites W2167464789 @default.
- W4290793757 cites W2168545543 @default.
- W4290793757 cites W2326608777 @default.
- W4290793757 cites W2354444772 @default.
- W4290793757 cites W2375360913 @default.
- W4290793757 cites W2521294629 @default.
- W4290793757 cites W2525908286 @default.
- W4290793757 cites W2551237711 @default.
- W4290793757 cites W2597711797 @default.
- W4290793757 cites W2606481249 @default.
- W4290793757 cites W2742698095 @default.
- W4290793757 cites W2773698404 @default.
- W4290793757 cites W2796350333 @default.
- W4290793757 cites W2796411194 @default.
- W4290793757 cites W2885691657 @default.
- W4290793757 cites W2886373066 @default.
- W4290793757 cites W2886399855 @default.
- W4290793757 cites W2894721422 @default.
- W4290793757 cites W2898648184 @default.
- W4290793757 cites W2941903190 @default.
- W4290793757 cites W2971983803 @default.
- W4290793757 cites W2972102107 @default.
- W4290793757 cites W2979725818 @default.
- W4290793757 cites W2985306777 @default.
- W4290793757 cites W2988132295 @default.
- W4290793757 cites W2990547440 @default.
- W4290793757 cites W3005742203 @default.
- W4290793757 cites W3015397552 @default.
- W4290793757 cites W3049195590 @default.
- W4290793757 cites W3098381363 @default.
- W4290793757 cites W3118615836 @default.
- W4290793757 cites W3126956087 @default.
- W4290793757 cites W3127991071 @default.
- W4290793757 cites W3164464653 @default.
- W4290793757 cites W3197233575 @default.
- W4290793757 cites W3203106957 @default.
- W4290793757 cites W3205926832 @default.
- W4290793757 cites W4214847386 @default.
- W4290793757 cites W4240942882 @default.
- W4290793757 cites W4246976582 @default.
- W4290793757 cites W4248163571 @default.
- W4290793757 cites W4290794143 @default.
- W4290793757 doi "https://doi.org/10.1001/jamaneurol.2022.1520" @default.