FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290804010> ?p ?o ?g. }

• W4290804010 abstract "Abstract • Background : There is no guideline or consensus on target delineations of stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC). Two different modes of target delineation are compared to identify a superior one beneficial for improvement of outcomes.• Methods : The study is a single-center, randomized phase II trial. Patients are randomly allocated to two groups with different delineations of planning target volume (PTV) of SBRT followed by a same chemotherapy regimen. Patients in Arm A receive uniform expansions of gross tumor volume (GTV) to form PTV, while PTV is contoured by non-uniform expansions of GTV based on recurrence patterns in Arm B. The primary endpoint is 1-year local control rate (1y-LC), and the secondary endpoints are disease progression-free survival (PFS), overall survival (OS), and treatment-related toxicity. Radiotherapy-induced adverse events (AEs) are recorded according to Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer (RTOG/EORTC), and chemotherapy AEs are graded according to Common Terminology Criteria for Adverse Events version 5.0 (CTCAE 5.0). This trial protocol has been approved by the Ethics committee of Changhai hospital. The ethics number is CHEC2020-099.• Discussion : Empirical uniform expansions of GTV is commonly practiced in most centers for delineations of PTV. However, limited evidence has confirmed potential benefits of this method. Therefore, we designed this prospective phase II study to investigate the hypothesis that better outcomes are found in the proposed method in our previous study than that used now.• Trial registration : Registration number: NCT04699539. Date of registration: 07 January, 2021." @default.
• W4290804010 created "2022-08-12" @default.
• W4290804010 creator A5005357118 @default.
• W4290804010 creator A5013852616 @default.
• W4290804010 creator A5018346512 @default.
• W4290804010 creator A5019384502 @default.
• W4290804010 creator A5032728697 @default.
• W4290804010 creator A5039287818 @default.
• W4290804010 creator A5040987305 @default.
• W4290804010 creator A5045929828 @default.
• W4290804010 creator A5047686040 @default.
• W4290804010 date "2022-08-11" @default.
• W4290804010 modified "2023-09-27" @default.
• W4290804010 title "Uniform expansion vs. non-uniform expansion of gross tumor volume based on recurrence patterns to form planning target volume of stereotactic body radiation therapy for locally advanced pancreatic cancer: protocol of a randomized phase II study" @default.
• W4290804010 cites W2098707349 @default.
• W4290804010 cites W2136706275 @default.
• W4290804010 cites W2151253787 @default.
• W4290804010 cites W2165480504 @default.
• W4290804010 cites W2412717755 @default.
• W4290804010 cites W2581973599 @default.
• W4290804010 cites W2752654580 @default.
• W4290804010 cites W2753159742 @default.
• W4290804010 cites W2889748477 @default.
• W4290804010 cites W2903623792 @default.
• W4290804010 cites W2913845257 @default.
• W4290804010 cites W2914166141 @default.
• W4290804010 cites W2921399058 @default.
• W4290804010 cites W2947955936 @default.
• W4290804010 cites W3010510895 @default.
• W4290804010 cites W3037749106 @default.
• W4290804010 cites W3042568371 @default.
• W4290804010 cites W3084093136 @default.
• W4290804010 cites W3085816397 @default.
• W4290804010 cites W3096980206 @default.
• W4290804010 cites W3098332911 @default.
• W4290804010 cites W3099435449 @default.
• W4290804010 cites W3110843904 @default.
• W4290804010 cites W3118165733 @default.
• W4290804010 cites W3181728629 @default.
• W4290804010 cites W4206841660 @default.
• W4290804010 cites W4211253487 @default.
• W4290804010 cites W4225845169 @default.
• W4290804010 cites W4226238781 @default.
• W4290804010 doi "https://doi.org/10.21203/rs.3.rs-1919548/v1" @default.
• W4290804010 hasPublicationYear "2022" @default.
• W4290804010 type Work @default.
• W4290804010 citedByCount "0" @default.
• W4290804010 crossrefType "posted-content" @default.
• W4290804010 hasAuthorship W4290804010A5005357118 @default.
• W4290804010 hasAuthorship W4290804010A5013852616 @default.
• W4290804010 hasAuthorship W4290804010A5018346512 @default.
• W4290804010 hasAuthorship W4290804010A5019384502 @default.
• W4290804010 hasAuthorship W4290804010A5032728697 @default.
• W4290804010 hasAuthorship W4290804010A5039287818 @default.
• W4290804010 hasAuthorship W4290804010A5040987305 @default.
• W4290804010 hasAuthorship W4290804010A5045929828 @default.
• W4290804010 hasAuthorship W4290804010A5047686040 @default.
• W4290804010 hasBestOaLocation W42908040101 @default.
• W4290804010 hasConcept C121608353 @default.
• W4290804010 hasConcept C126322002 @default.
• W4290804010 hasConcept C142724271 @default.
• W4290804010 hasConcept C143998085 @default.
• W4290804010 hasConcept C197934379 @default.
• W4290804010 hasConcept C203092338 @default.
• W4290804010 hasConcept C2777793932 @default.
• W4290804010 hasConcept C2780182762 @default.
• W4290804010 hasConcept C2780210213 @default.
• W4290804010 hasConcept C2781413609 @default.
• W4290804010 hasConcept C2989005 @default.
• W4290804010 hasConcept C509974204 @default.
• W4290804010 hasConcept C535046627 @default.
• W4290804010 hasConcept C71924100 @default.
• W4290804010 hasConceptScore W4290804010C121608353 @default.
• W4290804010 hasConceptScore W4290804010C126322002 @default.
• W4290804010 hasConceptScore W4290804010C142724271 @default.
• W4290804010 hasConceptScore W4290804010C143998085 @default.
• W4290804010 hasConceptScore W4290804010C197934379 @default.
• W4290804010 hasConceptScore W4290804010C203092338 @default.
• W4290804010 hasConceptScore W4290804010C2777793932 @default.
• W4290804010 hasConceptScore W4290804010C2780182762 @default.
• W4290804010 hasConceptScore W4290804010C2780210213 @default.
• W4290804010 hasConceptScore W4290804010C2781413609 @default.
• W4290804010 hasConceptScore W4290804010C2989005 @default.
• W4290804010 hasConceptScore W4290804010C509974204 @default.
• W4290804010 hasConceptScore W4290804010C535046627 @default.
• W4290804010 hasConceptScore W4290804010C71924100 @default.
• W4290804010 hasLocation W42908040101 @default.
• W4290804010 hasOpenAccess W4290804010 @default.
• W4290804010 hasPrimaryLocation W42908040101 @default.
• W4290804010 hasRelatedWork W1132082835 @default.
• W4290804010 hasRelatedWork W1694442327 @default.
• W4290804010 hasRelatedWork W2085488843 @default.
• W4290804010 hasRelatedWork W2225638675 @default.
• W4290804010 hasRelatedWork W2233648844 @default.
• W4290804010 hasRelatedWork W3031152052 @default.
• W4290804010 hasRelatedWork W3091031604 @default.
• W4290804010 hasRelatedWork W4253754137 @default.
• W4290804010 hasRelatedWork W4307349053 @default.
• W4290804010 hasRelatedWork W787893004 @default.
• W4290804010 isParatext "false" @default.

• next