Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290804051> ?p ?o ?g. }
- W4290804051 endingPage "1112" @default.
- W4290804051 startingPage "1106" @default.
- W4290804051 abstract "Background Pesticide self-poisoning is a global clinical and public health problem. While self-poisoning with insecticides and herbicides has been extensively studied, there is minimal literature on acute fungicide self-poisoning. We aimed to study the clinical course and outcome of fungicide self-poisoned patients recruited to a prospective cohort in Sri Lanka.Methods We conducted a prospective study of patients presenting with fungicide self-poisoning to nine hospitals in Sri Lanka between 2002 and 2020. Patients were enrolled by clinical research assistants, with clinical outcomes being recorded at regular review for each patient.Results We identified 337 cases of self-poisoning with fungicides (alcohol as only co-ingestant), including 28 different fungicides across 5 different fungicide classes. Median time from ingestion to examination was 3.1 (1.8–5.7) h. Nearly all presented to hospital fully conscious (GCS 15, 15–15)— only 27 patients (8.0%) presented with reduced GCS (<15) and only 2 (0.6%) had GCS 3/15. Most patients (333/337, 98.8%) made a full recovery, of whom only eight (2.37%) required intubation and ventilation. Four patients died (case fatality rate: 1.2%; 95% CI 0.0–23.4) after ingestion of edifenphos (n = 2), propamocarb and pyraclostrobin.Conclusion Fungicide self-poisoning appears to be less hazardous than insecticide or herbicide self-poisoning, with a substantially lower case fatality in the same cohort. Edifenphos is an exception to this ‘less toxic’ rule; as a WHO Class Ib highly hazardous pesticide, we recommend its withdrawal from, and replacement in, global agricultural practice. Propamocarb should be listed in the WHO hazard classification as propamocarb hydrochloride to reflect the higher toxicity of the common agricultural formulation. Pyraclostrobin currently has no WHO classification; one is urgently required now that its ingestion has now been linked the death of a patient. Additional prospective clinical data on fungicide self-poisoning is required to expand knowledge on the effects of these diverse compounds." @default.
- W4290804051 created "2022-08-12" @default.
- W4290804051 creator A5002182517 @default.
- W4290804051 creator A5018480780 @default.
- W4290804051 creator A5018841472 @default.
- W4290804051 creator A5040371388 @default.
- W4290804051 creator A5055738358 @default.
- W4290804051 creator A5067116503 @default.
- W4290804051 date "2022-08-11" @default.
- W4290804051 modified "2023-09-25" @default.
- W4290804051 title "Acute fungicide self-poisoning - a prospective case series" @default.
- W4290804051 cites W1557917738 @default.
- W4290804051 cites W2013282241 @default.
- W4290804051 cites W2015575590 @default.
- W4290804051 cites W2045902763 @default.
- W4290804051 cites W2050617259 @default.
- W4290804051 cites W2066921603 @default.
- W4290804051 cites W2089994192 @default.
- W4290804051 cites W2093938843 @default.
- W4290804051 cites W2105958292 @default.
- W4290804051 cites W2115114914 @default.
- W4290804051 cites W2118706753 @default.
- W4290804051 cites W2126450935 @default.
- W4290804051 cites W2142424976 @default.
- W4290804051 cites W2149111967 @default.
- W4290804051 cites W2151546268 @default.
- W4290804051 cites W2154546659 @default.
- W4290804051 cites W2159543716 @default.
- W4290804051 cites W2166439728 @default.
- W4290804051 cites W2195237289 @default.
- W4290804051 cites W2318680930 @default.
- W4290804051 cites W2576759533 @default.
- W4290804051 cites W2593142635 @default.
- W4290804051 cites W2612183699 @default.
- W4290804051 cites W2626162504 @default.
- W4290804051 cites W2744735691 @default.
- W4290804051 cites W2746768162 @default.
- W4290804051 cites W2767540747 @default.
- W4290804051 cites W2809280457 @default.
- W4290804051 cites W2901326859 @default.
- W4290804051 cites W2972611968 @default.
- W4290804051 cites W3012487842 @default.
- W4290804051 cites W3157486828 @default.
- W4290804051 cites W3159885350 @default.
- W4290804051 doi "https://doi.org/10.1080/15563650.2022.2105710" @default.
- W4290804051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35950874" @default.
- W4290804051 hasPublicationYear "2022" @default.
- W4290804051 type Work @default.
- W4290804051 citedByCount "0" @default.
- W4290804051 crossrefType "journal-article" @default.
- W4290804051 hasAuthorship W4290804051A5002182517 @default.
- W4290804051 hasAuthorship W4290804051A5018480780 @default.
- W4290804051 hasAuthorship W4290804051A5018841472 @default.
- W4290804051 hasAuthorship W4290804051A5040371388 @default.
- W4290804051 hasAuthorship W4290804051A5055738358 @default.
- W4290804051 hasAuthorship W4290804051A5067116503 @default.
- W4290804051 hasBestOaLocation W42908040511 @default.
- W4290804051 hasConcept C126322002 @default.
- W4290804051 hasConcept C141071460 @default.
- W4290804051 hasConcept C187316915 @default.
- W4290804051 hasConcept C188816634 @default.
- W4290804051 hasConcept C193230392 @default.
- W4290804051 hasConcept C194828623 @default.
- W4290804051 hasConcept C2908647359 @default.
- W4290804051 hasConcept C3017944768 @default.
- W4290804051 hasConcept C33070731 @default.
- W4290804051 hasConcept C59822182 @default.
- W4290804051 hasConcept C71924100 @default.
- W4290804051 hasConcept C74600772 @default.
- W4290804051 hasConcept C86803240 @default.
- W4290804051 hasConcept C99454951 @default.
- W4290804051 hasConceptScore W4290804051C126322002 @default.
- W4290804051 hasConceptScore W4290804051C141071460 @default.
- W4290804051 hasConceptScore W4290804051C187316915 @default.
- W4290804051 hasConceptScore W4290804051C188816634 @default.
- W4290804051 hasConceptScore W4290804051C193230392 @default.
- W4290804051 hasConceptScore W4290804051C194828623 @default.
- W4290804051 hasConceptScore W4290804051C2908647359 @default.
- W4290804051 hasConceptScore W4290804051C3017944768 @default.
- W4290804051 hasConceptScore W4290804051C33070731 @default.
- W4290804051 hasConceptScore W4290804051C59822182 @default.
- W4290804051 hasConceptScore W4290804051C71924100 @default.
- W4290804051 hasConceptScore W4290804051C74600772 @default.
- W4290804051 hasConceptScore W4290804051C86803240 @default.
- W4290804051 hasConceptScore W4290804051C99454951 @default.
- W4290804051 hasIssue "10" @default.
- W4290804051 hasLocation W42908040511 @default.
- W4290804051 hasLocation W42908040512 @default.
- W4290804051 hasOpenAccess W4290804051 @default.
- W4290804051 hasPrimaryLocation W42908040511 @default.
- W4290804051 hasRelatedWork W113810927 @default.
- W4290804051 hasRelatedWork W1586374228 @default.
- W4290804051 hasRelatedWork W2003938723 @default.
- W4290804051 hasRelatedWork W2047967234 @default.
- W4290804051 hasRelatedWork W2118496982 @default.
- W4290804051 hasRelatedWork W2364998975 @default.
- W4290804051 hasRelatedWork W2369162477 @default.
- W4290804051 hasRelatedWork W2439875401 @default.