Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290804136> ?p ?o ?g. }
- W4290804136 abstract "Bacteriophages and bacteriophage-derived peptidoglycan hydrolases (endolysins) present promising alternatives for the treatment of infections caused by multidrug resistant Gram-negative and Gram-positive pathogens. In this study, Gp105, a putative lysozyme murein hydrolase from Enterobacter phage myPSH1140 was characterized in silico, in vitro as well as in vivo using the purified protein. Gp105 contains a T4-type lysozyme-like domain (IPR001165) and belongs to Glycoside hydrolase family 24 (IPR002196). The putative endolysin indeed had strong antibacterial activity against Gram-negative pathogens, including E. cloacae, K. pneumoniae, P. aeruginosa, S. marcescens, Citrobacter sp., and A. baumannii. Also, an in vitro peptidoglycan hydrolysis assay showed strong activity against purified peptidoglycans. This study demonstrates the potential of Gp105 to be used as an antibacterial protein to combat Gram-negative pathogens." @default.
- W4290804136 created "2022-08-12" @default.
- W4290804136 creator A5009761895 @default.
- W4290804136 creator A5027829626 @default.
- W4290804136 creator A5037954596 @default.
- W4290804136 creator A5052900622 @default.
- W4290804136 creator A5059752530 @default.
- W4290804136 creator A5062007050 @default.
- W4290804136 creator A5073887845 @default.
- W4290804136 creator A5087261914 @default.
- W4290804136 date "2022-09-20" @default.
- W4290804136 modified "2023-10-01" @default.
- W4290804136 title "A Lysozyme Murein Hydrolase with Broad-Spectrum Antibacterial Activity from Enterobacter Phage myPSH1140" @default.
- W4290804136 cites W1848139833 @default.
- W4290804136 cites W1987250042 @default.
- W4290804136 cites W2024931582 @default.
- W4290804136 cites W2047943475 @default.
- W4290804136 cites W2052163430 @default.
- W4290804136 cites W2063524891 @default.
- W4290804136 cites W2082110408 @default.
- W4290804136 cites W2087379714 @default.
- W4290804136 cites W2100402024 @default.
- W4290804136 cites W2105486091 @default.
- W4290804136 cites W2148250698 @default.
- W4290804136 cites W2347102183 @default.
- W4290804136 cites W2594607607 @default.
- W4290804136 cites W2727915066 @default.
- W4290804136 cites W2769123627 @default.
- W4290804136 cites W2793068569 @default.
- W4290804136 cites W2913138027 @default.
- W4290804136 cites W2919748751 @default.
- W4290804136 cites W2924109378 @default.
- W4290804136 cites W3005978026 @default.
- W4290804136 cites W3011719258 @default.
- W4290804136 cites W3018504578 @default.
- W4290804136 cites W3037770163 @default.
- W4290804136 cites W3092273878 @default.
- W4290804136 cites W3134867396 @default.
- W4290804136 cites W3177879102 @default.
- W4290804136 cites W3201434055 @default.
- W4290804136 cites W3209519038 @default.
- W4290804136 cites W4019147 @default.
- W4290804136 cites W4205274496 @default.
- W4290804136 cites W4206677002 @default.
- W4290804136 cites W4223481392 @default.
- W4290804136 doi "https://doi.org/10.1128/aac.00506-22" @default.
- W4290804136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35950843" @default.
- W4290804136 hasPublicationYear "2022" @default.
- W4290804136 type Work @default.
- W4290804136 citedByCount "6" @default.
- W4290804136 countsByYear W42908041362022 @default.
- W4290804136 countsByYear W42908041362023 @default.
- W4290804136 crossrefType "journal-article" @default.
- W4290804136 hasAuthorship W4290804136A5009761895 @default.
- W4290804136 hasAuthorship W4290804136A5027829626 @default.
- W4290804136 hasAuthorship W4290804136A5037954596 @default.
- W4290804136 hasAuthorship W4290804136A5052900622 @default.
- W4290804136 hasAuthorship W4290804136A5059752530 @default.
- W4290804136 hasAuthorship W4290804136A5062007050 @default.
- W4290804136 hasAuthorship W4290804136A5073887845 @default.
- W4290804136 hasAuthorship W4290804136A5087261914 @default.
- W4290804136 hasBestOaLocation W42908041361 @default.
- W4290804136 hasConcept C104317684 @default.
- W4290804136 hasConcept C181199279 @default.
- W4290804136 hasConcept C22538091 @default.
- W4290804136 hasConcept C2776051709 @default.
- W4290804136 hasConcept C2776441376 @default.
- W4290804136 hasConcept C2776634448 @default.
- W4290804136 hasConcept C2776966407 @default.
- W4290804136 hasConcept C2777402170 @default.
- W4290804136 hasConcept C2778910516 @default.
- W4290804136 hasConcept C2778983983 @default.
- W4290804136 hasConcept C547475151 @default.
- W4290804136 hasConcept C55493867 @default.
- W4290804136 hasConcept C86803240 @default.
- W4290804136 hasConcept C89423630 @default.
- W4290804136 hasConceptScore W4290804136C104317684 @default.
- W4290804136 hasConceptScore W4290804136C181199279 @default.
- W4290804136 hasConceptScore W4290804136C22538091 @default.
- W4290804136 hasConceptScore W4290804136C2776051709 @default.
- W4290804136 hasConceptScore W4290804136C2776441376 @default.
- W4290804136 hasConceptScore W4290804136C2776634448 @default.
- W4290804136 hasConceptScore W4290804136C2776966407 @default.
- W4290804136 hasConceptScore W4290804136C2777402170 @default.
- W4290804136 hasConceptScore W4290804136C2778910516 @default.
- W4290804136 hasConceptScore W4290804136C2778983983 @default.
- W4290804136 hasConceptScore W4290804136C547475151 @default.
- W4290804136 hasConceptScore W4290804136C55493867 @default.
- W4290804136 hasConceptScore W4290804136C86803240 @default.
- W4290804136 hasConceptScore W4290804136C89423630 @default.
- W4290804136 hasIssue "9" @default.
- W4290804136 hasLocation W42908041361 @default.
- W4290804136 hasLocation W42908041362 @default.
- W4290804136 hasLocation W42908041363 @default.
- W4290804136 hasLocation W42908041364 @default.
- W4290804136 hasOpenAccess W4290804136 @default.
- W4290804136 hasPrimaryLocation W42908041361 @default.
- W4290804136 hasRelatedWork W2007976859 @default.
- W4290804136 hasRelatedWork W2071154828 @default.
- W4290804136 hasRelatedWork W2100402024 @default.