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- W4290804292 abstract "Biomedical engineering solutions to mankind have come with some of the most prompting ideas resolving major issues, from which bone healing scaffolds are one of its kind. The outcome of bone scaffolds has facilitated engineering as well as medical sciences in uncomplicated tissue healing methods of bones and organs. Earlier, many studies were performed on the appropriate designing of bone scaffolding, but this study spotlights on the designing methodology and topological optimisation of the scaffold. This study has been performed on an extracted segment of femur bone, further modifying it to a three-dimensional scaffold using computer aided design (CAD) software. Some leading edge software, like Materialize Mimics, Autodesk Meshmixer, and Fusion 360, have been employed for gaining desired results with optimal accuracy. Topological optimisation of scaffolds has led to its increased porosity along with appreciable material prevention. In case of any damage in the bone structure, the scaffold shall be placed and fixed to that section and this increased porosity shall be beneficial for providing the environment for cell regeneration which will aid in better formation of bone tissue. The scaffold porosity would also provide better fixture and strength to the structure after being implanted into the body. The deduction of excess material would reduce the overall manufacturing cost of the scaffold elevating its affordability to penurious patients." @default.
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- W4290804292 date "2022-07-28" @default.
- W4290804292 modified "2023-09-27" @default.
- W4290804292 title "Topological Design Optimisation of Tissue Engineering Scaffolds" @default.
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- W4290804292 doi "https://doi.org/10.1002/9781119755074.ch25" @default.
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