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- W4290839074 abstract "For hepatocellular carcinoma, the IMbrave150 trial demonstrated that combination atezolizumab and bevacizumab had significantly better overall survival compared with sorafenib in patients with unresectable disease. However, as more immune checkpoint inhibitors are approved as first-line agents in gastrointestinal cancers, there have been few reports on whether sequential PD-1/PD-L1 blockade is beneficial in the treatment of these diseases. We present a patient with hepatocellular carcinoma who had disease progression on atezolizumab, a PD-L1 inhibitor, but subsequently had a remarkable response to pembrolizumab, a PD-1 inhibitor." @default.
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- W4290839074 date "2022-08-01" @default.
- W4290839074 modified "2023-09-27" @default.
- W4290839074 title "Response to PD-1 inhibitor after progression on PD-L1 inhibitor in advanced HCC" @default.
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- W4290839074 doi "https://doi.org/10.1136/bcr-2022-250009" @default.
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