Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290930504> ?p ?o ?g. }
- W4290930504 abstract "Growth rate and body size are complex traits that contribute to the fitness of organisms. The identification of loci that underlie differences in these traits provides insights into the genetic contributions to development. Leveraging Caenorhabditis elegans as a tractable metazoan model for quantitative genetics, we can identify genomic regions that underlie differences in growth. We measured postembryonic growth of the laboratory-adapted wild-type strain (N2) and a wild strain from Hawaii (CB4856) and found differences in body size. Using linkage mapping, we identified three distinct quantitative trait loci (QTL) on chromosomes IV, V, and X that are associated with variation in body growth. We further examined these growth-associated quantitative trait loci using chromosome substitution strains and near-isogenic lines and validated the chromosome X quantitative trait loci. In addition, we generated a list of candidate genes for the chromosome X quantitative trait loci. These genes could potentially contribute to differences in animal growth and should be evaluated in subsequent studies. Our work reveals the genetic architecture underlying animal growth variation and highlights the genetic complexity of growth in Caenorhabditis elegans natural populations." @default.
- W4290930504 created "2022-08-13" @default.
- W4290930504 creator A5013550657 @default.
- W4290930504 creator A5078198741 @default.
- W4290930504 date "2022-08-12" @default.
- W4290930504 modified "2023-09-25" @default.
- W4290930504 title "Linkage mapping reveals loci that underlie differences in <i>Caenorhabditis elegans</i> growth" @default.
- W4290930504 cites W1489110007 @default.
- W4290930504 cites W1533255176 @default.
- W4290930504 cites W1998224653 @default.
- W4290930504 cites W2003787585 @default.
- W4290930504 cites W2022087979 @default.
- W4290930504 cites W2024958903 @default.
- W4290930504 cites W2038489248 @default.
- W4290930504 cites W2043949040 @default.
- W4290930504 cites W2060435573 @default.
- W4290930504 cites W2063661977 @default.
- W4290930504 cites W2065938201 @default.
- W4290930504 cites W2076397118 @default.
- W4290930504 cites W2077896867 @default.
- W4290930504 cites W2089384092 @default.
- W4290930504 cites W2096837660 @default.
- W4290930504 cites W2098188916 @default.
- W4290930504 cites W2102218399 @default.
- W4290930504 cites W2113906105 @default.
- W4290930504 cites W2117851139 @default.
- W4290930504 cites W2134556357 @default.
- W4290930504 cites W2161476009 @default.
- W4290930504 cites W2258952182 @default.
- W4290930504 cites W2519132385 @default.
- W4290930504 cites W2529350482 @default.
- W4290930504 cites W2605441431 @default.
- W4290930504 cites W2626606138 @default.
- W4290930504 cites W2735593947 @default.
- W4290930504 cites W2897066599 @default.
- W4290930504 cites W2935729442 @default.
- W4290930504 cites W2949271737 @default.
- W4290930504 cites W2955632151 @default.
- W4290930504 cites W2972766454 @default.
- W4290930504 cites W3021811794 @default.
- W4290930504 cites W3133564855 @default.
- W4290930504 cites W3142233419 @default.
- W4290930504 cites W3181865545 @default.
- W4290930504 cites W4205702565 @default.
- W4290930504 cites W4224264649 @default.
- W4290930504 cites W4225816414 @default.
- W4290930504 cites W4242171364 @default.
- W4290930504 doi "https://doi.org/10.1093/g3journal/jkac207" @default.
- W4290930504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35961034" @default.
- W4290930504 hasPublicationYear "2022" @default.
- W4290930504 type Work @default.
- W4290930504 citedByCount "2" @default.
- W4290930504 countsByYear W42909305042022 @default.
- W4290930504 countsByYear W42909305042023 @default.
- W4290930504 crossrefType "journal-article" @default.
- W4290930504 hasAuthorship W4290930504A5013550657 @default.
- W4290930504 hasAuthorship W4290930504A5078198741 @default.
- W4290930504 hasBestOaLocation W42909305041 @default.
- W4290930504 hasConcept C104317684 @default.
- W4290930504 hasConcept C106934330 @default.
- W4290930504 hasConcept C127716648 @default.
- W4290930504 hasConcept C142870003 @default.
- W4290930504 hasConcept C199360897 @default.
- W4290930504 hasConcept C2778944004 @default.
- W4290930504 hasConcept C30481170 @default.
- W4290930504 hasConcept C41008148 @default.
- W4290930504 hasConcept C51255272 @default.
- W4290930504 hasConcept C54355233 @default.
- W4290930504 hasConcept C68873052 @default.
- W4290930504 hasConcept C78458016 @default.
- W4290930504 hasConcept C81941488 @default.
- W4290930504 hasConcept C86803240 @default.
- W4290930504 hasConcept C9287583 @default.
- W4290930504 hasConceptScore W4290930504C104317684 @default.
- W4290930504 hasConceptScore W4290930504C106934330 @default.
- W4290930504 hasConceptScore W4290930504C127716648 @default.
- W4290930504 hasConceptScore W4290930504C142870003 @default.
- W4290930504 hasConceptScore W4290930504C199360897 @default.
- W4290930504 hasConceptScore W4290930504C2778944004 @default.
- W4290930504 hasConceptScore W4290930504C30481170 @default.
- W4290930504 hasConceptScore W4290930504C41008148 @default.
- W4290930504 hasConceptScore W4290930504C51255272 @default.
- W4290930504 hasConceptScore W4290930504C54355233 @default.
- W4290930504 hasConceptScore W4290930504C68873052 @default.
- W4290930504 hasConceptScore W4290930504C78458016 @default.
- W4290930504 hasConceptScore W4290930504C81941488 @default.
- W4290930504 hasConceptScore W4290930504C86803240 @default.
- W4290930504 hasConceptScore W4290930504C9287583 @default.
- W4290930504 hasIssue "10" @default.
- W4290930504 hasLocation W42909305041 @default.
- W4290930504 hasLocation W42909305042 @default.
- W4290930504 hasLocation W42909305043 @default.
- W4290930504 hasOpenAccess W4290930504 @default.
- W4290930504 hasPrimaryLocation W42909305041 @default.
- W4290930504 hasRelatedWork W155554328 @default.
- W4290930504 hasRelatedWork W2124506238 @default.
- W4290930504 hasRelatedWork W2125731289 @default.
- W4290930504 hasRelatedWork W2157166663 @default.
- W4290930504 hasRelatedWork W2159975710 @default.
- W4290930504 hasRelatedWork W2412733054 @default.