FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4290996927> ?p ?o ?g. }

• W4290996927 endingPage "2037" @default.
• W4290996927 startingPage "2037" @default.
• W4290996927 abstract "The health of pets is becoming a growing concern for the pet industry and its owners. Immunity is one of the foundational supports for health, thus developing a functional bioactive substance that can boost pets’ immunity is essential. Many studies have shown that casein phosphopeptide (CPP) and selenium (Se) can individually regulate immunity in many species, but there has been no reported research on the immunomodulatory function of casein phosphopeptide–selenium complex (CPP-Se). The objective of this study was to investigate the function of CPP-Se on immunomodulation in dogs. Twenty Beagle dogs were equally divided into two groups and fed either a control snack or a test snack supplemented with 0.03% CPP-Se for 30 days. Anticoagulated blood, serum and peripheral blood lymphocytes (PBL) were collected from dogs at 0 d, 10 d, 20 d and 30 d to detect the change in the number of immune cells and the expression of cytokine-related mRNAs and proteins. PBL isolated from blood were exposed to CPP-Se in vitro to measure the proliferative responses and cytokine-related mRNAs expression. During the time the test snack was fed, the number of lymphocytes increased significantly, whereas neutrophils and monocytes remained unaltered. The expression of interleukin-4 (IL-4), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), CD4 molecule (CD4) and CD8α molecule (CD8α) was up-regulated, while interleukin-1β (IL-1β) was down-regulated, and interleukin-10 (IL-10) declined initially and subsequently increased. ELISA detection revealed a significant increment in serum IL-4, IL-6, Immunoglobulin M (IgM) and IFN-γ, except for IgG. Furthermore, CPP-Se treatment increased the proliferation and the expression of cytokine-related mRNAs in PBL cultured in vitro. This is the first study to demonstrate that CPP-Se can improve immunity in the dog." @default.
• W4290996927 created "2022-08-13" @default.
• W4290996927 creator A5017535979 @default.
• W4290996927 creator A5026441951 @default.
• W4290996927 creator A5045799021 @default.
• W4290996927 creator A5049366807 @default.
• W4290996927 creator A5067938864 @default.
• W4290996927 creator A5082037805 @default.
• W4290996927 date "2022-08-10" @default.
• W4290996927 modified "2023-09-26" @default.
• W4290996927 title "Effects of Casein Phosphopeptide-Selenium Complex on the Immune Functions in Beagle Dogs" @default.
• W4290996927 cites W1512698525 @default.
• W4290996927 cites W1592620391 @default.
• W4290996927 cites W1890457554 @default.
• W4290996927 cites W1907301733 @default.
• W4290996927 cites W1938800942 @default.
• W4290996927 cites W1968095991 @default.
• W4290996927 cites W1969486314 @default.
• W4290996927 cites W1976024638 @default.
• W4290996927 cites W1977166747 @default.
• W4290996927 cites W1983523738 @default.
• W4290996927 cites W1986174872 @default.
• W4290996927 cites W1992468355 @default.
• W4290996927 cites W1995507886 @default.
• W4290996927 cites W1996477558 @default.
• W4290996927 cites W1996693696 @default.
• W4290996927 cites W2006412943 @default.
• W4290996927 cites W2009128497 @default.
• W4290996927 cites W2009761798 @default.
• W4290996927 cites W2038768947 @default.
• W4290996927 cites W2041292661 @default.
• W4290996927 cites W2053144662 @default.
• W4290996927 cites W2053634695 @default.
• W4290996927 cites W2065179496 @default.
• W4290996927 cites W2066699333 @default.
• W4290996927 cites W2068698748 @default.
• W4290996927 cites W2085212996 @default.
• W4290996927 cites W2106460021 @default.
• W4290996927 cites W2107277218 @default.
• W4290996927 cites W2114771448 @default.
• W4290996927 cites W2117589198 @default.
• W4290996927 cites W2129968545 @default.
• W4290996927 cites W2141064464 @default.
• W4290996927 cites W2150662513 @default.
• W4290996927 cites W2192080449 @default.
• W4290996927 cites W2212724436 @default.
• W4290996927 cites W2275687089 @default.
• W4290996927 cites W2307697300 @default.
• W4290996927 cites W2409180174 @default.
• W4290996927 cites W2413274786 @default.
• W4290996927 cites W2415320166 @default.
• W4290996927 cites W2508970134 @default.
• W4290996927 cites W2562400674 @default.
• W4290996927 cites W2605512323 @default.
• W4290996927 cites W2788422364 @default.
• W4290996927 cites W2889290358 @default.
• W4290996927 cites W2967011870 @default.
• W4290996927 cites W2973184681 @default.
• W4290996927 cites W3003630737 @default.
• W4290996927 cites W3006169940 @default.
• W4290996927 cites W3008561938 @default.
• W4290996927 cites W3023923910 @default.
• W4290996927 cites W3031032548 @default.
• W4290996927 cites W3090115900 @default.
• W4290996927 cites W3142805766 @default.
• W4290996927 cites W3196231552 @default.
• W4290996927 cites W3204527395 @default.
• W4290996927 cites W33353979 @default.
• W4290996927 cites W4205802918 @default.
• W4290996927 doi "https://doi.org/10.3390/ani12162037" @default.
• W4290996927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36009627" @default.
• W4290996927 hasPublicationYear "2022" @default.
• W4290996927 type Work @default.
• W4290996927 citedByCount "1" @default.
• W4290996927 countsByYear W42909969272023 @default.
• W4290996927 crossrefType "journal-article" @default.
• W4290996927 hasAuthorship W4290996927A5017535979 @default.
• W4290996927 hasAuthorship W4290996927A5026441951 @default.
• W4290996927 hasAuthorship W4290996927A5045799021 @default.
• W4290996927 hasAuthorship W4290996927A5049366807 @default.
• W4290996927 hasAuthorship W4290996927A5067938864 @default.
• W4290996927 hasAuthorship W4290996927A5082037805 @default.
• W4290996927 hasBestOaLocation W42909969271 @default.
• W4290996927 hasConcept C11960822 @default.
• W4290996927 hasConcept C126322002 @default.
• W4290996927 hasConcept C1621761 @default.
• W4290996927 hasConcept C167672396 @default.
• W4290996927 hasConcept C17991360 @default.
• W4290996927 hasConcept C185592680 @default.
• W4290996927 hasConcept C203014093 @default.
• W4290996927 hasConcept C2776142715 @default.
• W4290996927 hasConcept C2776820430 @default.
• W4290996927 hasConcept C2778690821 @default.
• W4290996927 hasConcept C2779341262 @default.
• W4290996927 hasConcept C2779933727 @default.
• W4290996927 hasConcept C55493867 @default.
• W4290996927 hasConcept C71924100 @default.
• W4290996927 hasConcept C74172505 @default.

• next