FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4291134585> ?p ?o ?g. }

• W4291134585 endingPage "5855" @default.
• W4291134585 startingPage "5836" @default.
• W4291134585 abstract "Liquid biopsies do promise a lot, but are they keeping it? In the past decade, additional novel biomarkers qualified to be called like that, of which, some took necessary hurdles resulting in FDA approval and clinical use. Some others are since a while around, well known and were once regarded to be a game changer in cancer diagnosis or cancer screening. But, during their clinical use limitations were observed from statistical significance and questions raised regarding their robustness, that eventually led to be dropped from associated clinical guidelines for certain applications including cancer diagnosis. The purpose of this review isn't to give a broad overview of all current liquid biopsy as biomarkers, weight them and promise a brighter future in cancer prevention, but rather to take a deeper look on two of those who do qualify to be called liquid biopsies now or then. These two are probably of greatest interest conceptually and methodically, and likely have the highest chances to be in clinical use soon, with a portfolio extension over their original conceptual usage. We aim to dig deeper beyond cancer diagnosis or cancer screening. Actually, we aim to review in depth extracellular vesicles (EVs) and compare with circulating tumour cells (CTCs). The latter methodology is partially FDA approved and in clinical use. We will lay out similarities as taking advantage of surface antigens on EVs and CTCs in case of characterization and quantification. But drawing readers' attention to downstream application based on capture/isolation methodology and simply on their overall nature, here apparently being living material eventually recoverable as CTCs are vs. dead material with transient effects on recipient cell as in case of EVs. All this we try to bring in perspective, compare and conclude towards which future direction we are aiming for, or should aim for. Do we announce a winner between CTCs vs EVs? No, but we provide good reasons to intensify research on them." @default.
• W4291134585 created "2022-08-13" @default.
• W4291134585 creator A5007481708 @default.
• W4291134585 creator A5010703886 @default.
• W4291134585 creator A5012934285 @default.
• W4291134585 creator A5026423236 @default.
• W4291134585 creator A5031031175 @default.
• W4291134585 creator A5033769350 @default.
• W4291134585 creator A5043858898 @default.
• W4291134585 creator A5058490197 @default.
• W4291134585 creator A5074477435 @default.
• W4291134585 creator A5090224526 @default.
• W4291134585 date "2022-01-01" @default.
• W4291134585 modified "2023-10-17" @default.
• W4291134585 title "Extracellular Vesicles and Circulating Tumour Cells - complementary liquid biopsies or standalone concepts?" @default.
• W4291134585 cites W11097077 @default.
• W4291134585 cites W1500925570 @default.
• W4291134585 cites W1548015278 @default.
• W4291134585 cites W1701091641 @default.
• W4291134585 cites W1762620449 @default.
• W4291134585 cites W1917588793 @default.
• W4291134585 cites W1959010197 @default.
• W4291134585 cites W1966568420 @default.
• W4291134585 cites W1966606134 @default.
• W4291134585 cites W1968562880 @default.
• W4291134585 cites W1971589201 @default.
• W4291134585 cites W1972070926 @default.
• W4291134585 cites W1984736273 @default.
• W4291134585 cites W1986971722 @default.
• W4291134585 cites W1989090719 @default.
• W4291134585 cites W1994636867 @default.
• W4291134585 cites W1999087873 @default.
• W4291134585 cites W1999729424 @default.
• W4291134585 cites W2007880623 @default.
• W4291134585 cites W2010916968 @default.
• W4291134585 cites W2011191202 @default.
• W4291134585 cites W2012987872 @default.
• W4291134585 cites W2013057431 @default.
• W4291134585 cites W2020215421 @default.
• W4291134585 cites W2022725154 @default.
• W4291134585 cites W2033612573 @default.
• W4291134585 cites W2036713216 @default.
• W4291134585 cites W2037607269 @default.
• W4291134585 cites W2044702943 @default.
• W4291134585 cites W2047554241 @default.
• W4291134585 cites W2053306127 @default.
• W4291134585 cites W2054874509 @default.
• W4291134585 cites W2055313665 @default.
• W4291134585 cites W2056777828 @default.
• W4291134585 cites W2057341417 @default.
• W4291134585 cites W2060387475 @default.
• W4291134585 cites W2069087935 @default.
• W4291134585 cites W2078877034 @default.
• W4291134585 cites W2085898732 @default.
• W4291134585 cites W2090360086 @default.
• W4291134585 cites W2093402985 @default.
• W4291134585 cites W2093758129 @default.
• W4291134585 cites W2096817916 @default.
• W4291134585 cites W2096843107 @default.
• W4291134585 cites W2099718495 @default.
• W4291134585 cites W2101151609 @default.
• W4291134585 cites W2101782801 @default.
• W4291134585 cites W2111662910 @default.
• W4291134585 cites W2111976640 @default.
• W4291134585 cites W2116268000 @default.
• W4291134585 cites W2116483002 @default.
• W4291134585 cites W2117305280 @default.
• W4291134585 cites W2118236274 @default.
• W4291134585 cites W2119764457 @default.
• W4291134585 cites W2121354606 @default.
• W4291134585 cites W2126855984 @default.
• W4291134585 cites W2137900362 @default.
• W4291134585 cites W2146006182 @default.
• W4291134585 cites W2147997814 @default.
• W4291134585 cites W2159401023 @default.
• W4291134585 cites W2159703296 @default.
• W4291134585 cites W2161862739 @default.
• W4291134585 cites W2163403599 @default.
• W4291134585 cites W2163760933 @default.
• W4291134585 cites W2169285092 @default.
• W4291134585 cites W2171298396 @default.
• W4291134585 cites W2178935826 @default.
• W4291134585 cites W2187976253 @default.
• W4291134585 cites W2222703707 @default.
• W4291134585 cites W2230871390 @default.
• W4291134585 cites W2259481044 @default.
• W4291134585 cites W2270706952 @default.
• W4291134585 cites W2272723077 @default.
• W4291134585 cites W2277004004 @default.
• W4291134585 cites W2295603197 @default.
• W4291134585 cites W2329826606 @default.
• W4291134585 cites W2335679869 @default.
• W4291134585 cites W2338474071 @default.
• W4291134585 cites W2340049980 @default.
• W4291134585 cites W2343797741 @default.
• W4291134585 cites W2344070586 @default.
• W4291134585 cites W2345715888 @default.
• W4291134585 cites W2420247920 @default.

• next