FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4291145259> ?p ?o ?g. }

• W4291145259 abstract "Our aim was to investigate the rate and topological profile of minor physical anomalies (MPAs) in adult patients with epilepsy with the use of the Méhes Scale, a comprehensive modern scale of dysmorphology. Consecutive epilepsy patients admitted for outpatient evaluation were included. Patients with comorbidities of neurodevelopmental origin (such as autism, severe intellectual disability, attention deficit hyperactivity disorder, schizophrenia, tic disorder, Tourette syndrome, bipolar disorder, specific learning disorder and specific language impairment) were excluded. All participants underwent physical examination with the use of the Méhes Scale for evaluation of MPAs, including 57 minor signs. The frequency and topological profile of MPAs were correlated to clinical patient data using Kruskal-Wallis, chi2 tests and logistic regression model. 235 patients were included, according to the following subgroups: acquired epilepsy (non-genetic, non-developmental etiology) [N = 63], temporal lobe epilepsy with hippocampal sclerosis (TLE with HS) [N = 27], epilepsy with cortical dysgenesis etiology [N = 29], cryptogenic epilepsy [N = 69] and idiopathic generalized epilepsy (IGE) [N = 47]. As controls, 30 healthy adults were recruited. The frequency of MPAs were significantly affected by the type of epilepsy [H(6) = 90.17; p < 0.001]. Pairwise comparisons showed that all patient groups except for acquired epilepsy were associated with increased frequency of MPAs (p < 0.001 in all cases). Furrowed tongue and high arched palate were more common compared to controls in all epilepsy subgroup except for TLE (p < 0.001 or p = 0.001 in all cases). A positive association was detected between the occurrence of MPAs and antiepileptic drug therapy resistance [Exp(B) = 4.19; CI 95% 1.37-12.80; p = 0.012]. MPAs are more common in patients with epilepsy, which corroborates the emerging concept of epilepsy as a neurodevelopmental disorder. Assessment of these signs may contribute to the clarification of the underlying etiology. Moreover, as increased frequency of MPAs may indicate pharmacoresistance, the identification of patients with high number of MPAs could allow evaluation for non-pharmacological treatment in time." @default.
• W4291145259 created "2022-08-13" @default.
• W4291145259 creator A5009813249 @default.
• W4291145259 creator A5018245360 @default.
• W4291145259 creator A5046296076 @default.
• W4291145259 creator A5047298880 @default.
• W4291145259 creator A5063792819 @default.
• W4291145259 creator A5069634240 @default.
• W4291145259 creator A5079492455 @default.
• W4291145259 creator A5088650463 @default.
• W4291145259 date "2022-08-12" @default.
• W4291145259 modified "2023-09-27" @default.
• W4291145259 title "Increased prevalence of minor physical anomalies in patients with epilepsy" @default.
• W4291145259 cites W1491122096 @default.
• W4291145259 cites W1569482162 @default.
• W4291145259 cites W1607732415 @default.
• W4291145259 cites W1920696238 @default.
• W4291145259 cites W1998084506 @default.
• W4291145259 cites W2005586126 @default.
• W4291145259 cites W2019614824 @default.
• W4291145259 cites W2026074212 @default.
• W4291145259 cites W2044829020 @default.
• W4291145259 cites W2056056958 @default.
• W4291145259 cites W2056181708 @default.
• W4291145259 cites W2056567212 @default.
• W4291145259 cites W2065266445 @default.
• W4291145259 cites W2085088543 @default.
• W4291145259 cites W2086663422 @default.
• W4291145259 cites W2087551864 @default.
• W4291145259 cites W2090176506 @default.
• W4291145259 cites W2093693020 @default.
• W4291145259 cites W2103892770 @default.
• W4291145259 cites W2106064197 @default.
• W4291145259 cites W2106786372 @default.
• W4291145259 cites W2116925336 @default.
• W4291145259 cites W2130375794 @default.
• W4291145259 cites W2130796597 @default.
• W4291145259 cites W2154800622 @default.
• W4291145259 cites W2156198928 @default.
• W4291145259 cites W2295527059 @default.
• W4291145259 cites W2326272814 @default.
• W4291145259 cites W2401038325 @default.
• W4291145259 cites W2403636565 @default.
• W4291145259 cites W2417742178 @default.
• W4291145259 cites W2474254452 @default.
• W4291145259 cites W2484211017 @default.
• W4291145259 cites W2567931818 @default.
• W4291145259 cites W2584752124 @default.
• W4291145259 cites W2592509339 @default.
• W4291145259 cites W2726666234 @default.
• W4291145259 cites W2976263851 @default.
• W4291145259 cites W3156073307 @default.
• W4291145259 cites W3171944524 @default.
• W4291145259 cites W3181755649 @default.
• W4291145259 doi "https://doi.org/10.1038/s41598-022-17853-1" @default.
• W4291145259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35962048" @default.
• W4291145259 hasPublicationYear "2022" @default.
• W4291145259 type Work @default.
• W4291145259 citedByCount "1" @default.
• W4291145259 countsByYear W42911452592023 @default.
• W4291145259 crossrefType "journal-article" @default.
• W4291145259 hasAuthorship W4291145259A5009813249 @default.
• W4291145259 hasAuthorship W4291145259A5018245360 @default.
• W4291145259 hasAuthorship W4291145259A5046296076 @default.
• W4291145259 hasAuthorship W4291145259A5047298880 @default.
• W4291145259 hasAuthorship W4291145259A5063792819 @default.
• W4291145259 hasAuthorship W4291145259A5069634240 @default.
• W4291145259 hasAuthorship W4291145259A5079492455 @default.
• W4291145259 hasAuthorship W4291145259A5088650463 @default.
• W4291145259 hasBestOaLocation W42911452591 @default.
• W4291145259 hasConcept C118552586 @default.
• W4291145259 hasConcept C126322002 @default.
• W4291145259 hasConcept C137627325 @default.
• W4291145259 hasConcept C187212893 @default.
• W4291145259 hasConcept C205778803 @default.
• W4291145259 hasConcept C2776703358 @default.
• W4291145259 hasConcept C2777597344 @default.
• W4291145259 hasConcept C2778186239 @default.
• W4291145259 hasConcept C2778538070 @default.
• W4291145259 hasConcept C2778734009 @default.
• W4291145259 hasConcept C2781099131 @default.
• W4291145259 hasConcept C71924100 @default.
• W4291145259 hasConceptScore W4291145259C118552586 @default.
• W4291145259 hasConceptScore W4291145259C126322002 @default.
• W4291145259 hasConceptScore W4291145259C137627325 @default.
• W4291145259 hasConceptScore W4291145259C187212893 @default.
• W4291145259 hasConceptScore W4291145259C205778803 @default.
• W4291145259 hasConceptScore W4291145259C2776703358 @default.
• W4291145259 hasConceptScore W4291145259C2777597344 @default.
• W4291145259 hasConceptScore W4291145259C2778186239 @default.
• W4291145259 hasConceptScore W4291145259C2778538070 @default.
• W4291145259 hasConceptScore W4291145259C2778734009 @default.
• W4291145259 hasConceptScore W4291145259C2781099131 @default.
• W4291145259 hasConceptScore W4291145259C71924100 @default.
• W4291145259 hasFunder F4320325904 @default.
• W4291145259 hasIssue "1" @default.
• W4291145259 hasLocation W42911452591 @default.
• W4291145259 hasLocation W42911452592 @default.
• W4291145259 hasLocation W42911452593 @default.
• W4291145259 hasOpenAccess W4291145259 @default.

• next