Matches in SemOpenAlex for { <https://semopenalex.org/work/W4291237112> ?p ?o ?g. }
- W4291237112 endingPage "103" @default.
- W4291237112 startingPage "97" @default.
- W4291237112 abstract "A series of new cannabidiol (CBD) derivatives were synthesized by employing hydrogenation reaction and click chemistry. Then, the cytotoxicity and anti-inflammatory activities of cannabinoid derivatives were determined. Compound 14 was found to have low cytotoxicity and high anti-inflammatory activity, and the anti-inflammatory mechanism of compound 14 was preliminarily explored, which inhibited the synthesis and release of the pro-inflammatory cytokine TNF-α. The experimental results were confirmed by docking analysis. The water solubility of compound 14 was determined. Based on the results, the structure-activity relationships (SARs) of the CBD derivatives were discussed for exploring novel anti-inflammatory drugs." @default.
- W4291237112 created "2022-08-13" @default.
- W4291237112 creator A5014310469 @default.
- W4291237112 creator A5015203715 @default.
- W4291237112 creator A5026850352 @default.
- W4291237112 creator A5037826469 @default.
- W4291237112 creator A5044611536 @default.
- W4291237112 creator A5066448103 @default.
- W4291237112 creator A5068076124 @default.
- W4291237112 creator A5080872035 @default.
- W4291237112 creator A5084234469 @default.
- W4291237112 creator A5087929515 @default.
- W4291237112 date "2022-10-01" @default.
- W4291237112 modified "2023-10-14" @default.
- W4291237112 title "New cannabidiol (CBD) derivatives: Synthesis, anti-inflammatory activity, and molecular docking" @default.
- W4291237112 cites W105963342 @default.
- W4291237112 cites W1762617857 @default.
- W4291237112 cites W1965037168 @default.
- W4291237112 cites W1971629816 @default.
- W4291237112 cites W1979886311 @default.
- W4291237112 cites W1987753836 @default.
- W4291237112 cites W1991547438 @default.
- W4291237112 cites W1992661831 @default.
- W4291237112 cites W2005241761 @default.
- W4291237112 cites W2018857922 @default.
- W4291237112 cites W2020466729 @default.
- W4291237112 cites W2020825180 @default.
- W4291237112 cites W2033174923 @default.
- W4291237112 cites W2034891821 @default.
- W4291237112 cites W2037208645 @default.
- W4291237112 cites W2052554412 @default.
- W4291237112 cites W2064119981 @default.
- W4291237112 cites W2087243986 @default.
- W4291237112 cites W2121284546 @default.
- W4291237112 cites W2270554953 @default.
- W4291237112 cites W2304213251 @default.
- W4291237112 cites W2588157389 @default.
- W4291237112 cites W2619979905 @default.
- W4291237112 cites W2887820457 @default.
- W4291237112 cites W2890071983 @default.
- W4291237112 cites W2901333595 @default.
- W4291237112 cites W2916643480 @default.
- W4291237112 cites W2948661070 @default.
- W4291237112 cites W2959089550 @default.
- W4291237112 cites W3015599722 @default.
- W4291237112 cites W3016615993 @default.
- W4291237112 cites W3082397071 @default.
- W4291237112 cites W3122765610 @default.
- W4291237112 cites W4210308909 @default.
- W4291237112 doi "https://doi.org/10.1016/j.phytol.2022.08.004" @default.
- W4291237112 hasPublicationYear "2022" @default.
- W4291237112 type Work @default.
- W4291237112 citedByCount "2" @default.
- W4291237112 countsByYear W42912371122023 @default.
- W4291237112 crossrefType "journal-article" @default.
- W4291237112 hasAuthorship W4291237112A5014310469 @default.
- W4291237112 hasAuthorship W4291237112A5015203715 @default.
- W4291237112 hasAuthorship W4291237112A5026850352 @default.
- W4291237112 hasAuthorship W4291237112A5037826469 @default.
- W4291237112 hasAuthorship W4291237112A5044611536 @default.
- W4291237112 hasAuthorship W4291237112A5066448103 @default.
- W4291237112 hasAuthorship W4291237112A5068076124 @default.
- W4291237112 hasAuthorship W4291237112A5080872035 @default.
- W4291237112 hasAuthorship W4291237112A5084234469 @default.
- W4291237112 hasAuthorship W4291237112A5087929515 @default.
- W4291237112 hasConcept C109316439 @default.
- W4291237112 hasConcept C118552586 @default.
- W4291237112 hasConcept C159110408 @default.
- W4291237112 hasConcept C170493617 @default.
- W4291237112 hasConcept C185592680 @default.
- W4291237112 hasConcept C202751555 @default.
- W4291237112 hasConcept C21951064 @default.
- W4291237112 hasConcept C2776895053 @default.
- W4291237112 hasConcept C2777056318 @default.
- W4291237112 hasConcept C2780871563 @default.
- W4291237112 hasConcept C41685203 @default.
- W4291237112 hasConcept C55493867 @default.
- W4291237112 hasConcept C71240020 @default.
- W4291237112 hasConcept C71924100 @default.
- W4291237112 hasConcept C86803240 @default.
- W4291237112 hasConcept C98274493 @default.
- W4291237112 hasConceptScore W4291237112C109316439 @default.
- W4291237112 hasConceptScore W4291237112C118552586 @default.
- W4291237112 hasConceptScore W4291237112C159110408 @default.
- W4291237112 hasConceptScore W4291237112C170493617 @default.
- W4291237112 hasConceptScore W4291237112C185592680 @default.
- W4291237112 hasConceptScore W4291237112C202751555 @default.
- W4291237112 hasConceptScore W4291237112C21951064 @default.
- W4291237112 hasConceptScore W4291237112C2776895053 @default.
- W4291237112 hasConceptScore W4291237112C2777056318 @default.
- W4291237112 hasConceptScore W4291237112C2780871563 @default.
- W4291237112 hasConceptScore W4291237112C41685203 @default.
- W4291237112 hasConceptScore W4291237112C55493867 @default.
- W4291237112 hasConceptScore W4291237112C71240020 @default.
- W4291237112 hasConceptScore W4291237112C71924100 @default.
- W4291237112 hasConceptScore W4291237112C86803240 @default.
- W4291237112 hasConceptScore W4291237112C98274493 @default.
- W4291237112 hasLocation W42912371121 @default.