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- W4291288978 abstract "Cyclophilins (Cyps) are a subgroup of peptidyl-prolyl cis-trans isomerases (PPIases) that contain a highly conserved domain of PPIases. Sixteen Cyps have been identified in humans, among which the functions of five classical Cyp subtypes (CypA, B, C, D, and 40) have been studied in more detail. Cyps are widely expressed in almost all human tissues and are involved in several intracellular signaling pathways such as oxidative stress, mitochondrial dysfunction, cell migration, and apoptosis. Several studies have also demonstrated that Cyps play an important role in the development of cardiovascular diseases, neurodegeneration, cancer, and other diseases. However, as regulators of intercellular communication, Cyps have increasingly attracted attention as a result of their implications in viral infection. The specific motifs of Cyps can be targeted by viral proteins and thus promote either a viral infection or an antiviral response. This review highlights the present understanding of Cyps in viral infection and immune response. These effects will facilitate revealing the molecular mechanisms of several diseases induced by viruses and may provide novel insight into the development of corresponding drug-based treatment methods." @default.
- W4291288978 created "2022-08-14" @default.
- W4291288978 creator A5002555523 @default.
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- W4291288978 date "2022-10-01" @default.
- W4291288978 modified "2023-10-18" @default.
- W4291288978 title "The role of cyclophilins in viral infection and the immune response" @default.
- W4291288978 cites W1485041694 @default.
- W4291288978 cites W1490406634 @default.
- W4291288978 cites W1964483580 @default.
- W4291288978 cites W1964818910 @default.
- W4291288978 cites W1966628077 @default.
- W4291288978 cites W1972607828 @default.
- W4291288978 cites W1974365008 @default.
- W4291288978 cites W1976499918 @default.
- W4291288978 cites W1982769227 @default.
- W4291288978 cites W1986512043 @default.
- W4291288978 cites W1986798222 @default.
- W4291288978 cites W1987371296 @default.
- W4291288978 cites W1989227615 @default.
- W4291288978 cites W1993870517 @default.
- W4291288978 cites W1995374823 @default.
- W4291288978 cites W2000058866 @default.
- W4291288978 cites W2000353968 @default.
- W4291288978 cites W2007006575 @default.
- W4291288978 cites W2009524774 @default.
- W4291288978 cites W2014620671 @default.
- W4291288978 cites W2015868830 @default.
- W4291288978 cites W2022527520 @default.
- W4291288978 cites W2023055347 @default.
- W4291288978 cites W2024060688 @default.
- W4291288978 cites W2027714304 @default.
- W4291288978 cites W2032815135 @default.
- W4291288978 cites W2033292209 @default.
- W4291288978 cites W2033763004 @default.
- W4291288978 cites W2042263540 @default.
- W4291288978 cites W2049205589 @default.
- W4291288978 cites W2050360019 @default.
- W4291288978 cites W2050996246 @default.
- W4291288978 cites W2051918018 @default.
- W4291288978 cites W2052820674 @default.
- W4291288978 cites W2054685824 @default.
- W4291288978 cites W2056009561 @default.
- W4291288978 cites W2060115202 @default.
- W4291288978 cites W2060140838 @default.
- W4291288978 cites W2062639699 @default.
- W4291288978 cites W2063602229 @default.
- W4291288978 cites W2065924458 @default.
- W4291288978 cites W2067545345 @default.
- W4291288978 cites W2069234080 @default.
- W4291288978 cites W2074719866 @default.
- W4291288978 cites W2078189159 @default.
- W4291288978 cites W2079724990 @default.
- W4291288978 cites W2080064179 @default.
- W4291288978 cites W2080999910 @default.
- W4291288978 cites W2081814597 @default.
- W4291288978 cites W2083886613 @default.
- W4291288978 cites W2096503469 @default.
- W4291288978 cites W2103020015 @default.
- W4291288978 cites W2108234265 @default.
- W4291288978 cites W2112179775 @default.
- W4291288978 cites W2112659240 @default.
- W4291288978 cites W2116396676 @default.
- W4291288978 cites W2130531186 @default.
- W4291288978 cites W2135561082 @default.
- W4291288978 cites W2136869761 @default.
- W4291288978 cites W2145644144 @default.
- W4291288978 cites W2151547533 @default.
- W4291288978 cites W2152561379 @default.
- W4291288978 cites W2155581909 @default.
- W4291288978 cites W2158730314 @default.
- W4291288978 cites W2160902450 @default.
- W4291288978 cites W2163242365 @default.
- W4291288978 cites W2167294127 @default.
- W4291288978 cites W2167559643 @default.
- W4291288978 cites W2167983086 @default.
- W4291288978 cites W2240080643 @default.
- W4291288978 cites W2252997710 @default.
- W4291288978 cites W2275470695 @default.
- W4291288978 cites W2313506770 @default.
- W4291288978 cites W2340594833 @default.
- W4291288978 cites W2387637186 @default.
- W4291288978 cites W2460825169 @default.
- W4291288978 cites W2525396082 @default.
- W4291288978 cites W2548997371 @default.
- W4291288978 cites W2560200715 @default.
- W4291288978 cites W2593608883 @default.
- W4291288978 cites W2622279238 @default.
- W4291288978 cites W2736261019 @default.
- W4291288978 cites W2740978635 @default.
- W4291288978 cites W2741162240 @default.
- W4291288978 cites W2773466365 @default.