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• W4291552010 abstract "We present a unique super-resolution stimulated Raman scattering (SRS) microscopy technique based on phase-shifted spatial frequency modulation (PSFM) under wide-field illumination, permitting super-resolution chemical imaging with single-pixel detection. Through projecting a series of the pump and Stokes laser patterns with varying spatial frequencies onto the sample and combining with the proposed π-phase shift, the higher spatial information can be rapidly retrieved by implementing the fast inverse Fourier-transform on the spatial frequency-encoded SRS data. We have derived the theory of the PSFM-SRS technique for super-resolution imaging. Our further modeling results confirm that PSFM-SRS microscopy provides a ∼2.2-fold improvement in spatial resolution but with a much-reduced laser excitation power density required as compared with conventional point-scan SRS microscopy, suggesting its potential for label-free super-resolution chemical imaging in cells and tissue." @default.
• W4291552010 created "2022-08-15" @default.
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• W4291552010 date "2022-08-31" @default.
• W4291552010 modified "2023-10-18" @default.
• W4291552010 title "Super-resolution stimulated Raman scattering microscopy with the phase-shifted spatial frequency modulation" @default.
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• W4291552010 doi "https://doi.org/10.1364/ol.463087" @default.
• W4291552010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36048702" @default.
• W4291552010 hasPublicationYear "2022" @default.
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