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- W4291666973 abstract "Abstract Behavioral and economic theory dictates that we decide between options based on their values. However, humans and animals eagerly seek information about uncertain future rewards, even when this information does not provide any objective value. This implies that decisions can be made by endowing information with subjective value and integrating it with the value of extrinsic rewards, but the mechanism is unknown. Using a novel multi-attribute decision making task we found that human and monkey value judgements are regulated by strikingly conserved computational principles, including how they compute the value of information and scale it with information’s timing and ability to resolve a specific form of uncertainty. We then identified a neural substrate in a highly conserved and ancient structure, the lateral habenula (LHb). LHb neurons signal the subjective value of choice options integrating the value of information with extrinsic rewards, and LHb activity both predicts and causally influences online decisions. Key input regions to LHb provide the necessary ingredients for these computations, but do not themselves signal an integrated value signal to guide multi attribute decisions. Our data thus identifies neural mechanisms of the conserved computations underlying multi-attribute, value-based decisions to seek information about the future." @default.
- W4291666973 created "2022-08-15" @default.
- W4291666973 creator A5009259014 @default.
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- W4291666973 date "2022-08-15" @default.
- W4291666973 modified "2023-10-06" @default.
- W4291666973 title "A neural mechanism for conserved value computations integrating information and rewards" @default.
- W4291666973 cites W1542275754 @default.
- W4291666973 cites W1543794893 @default.
- W4291666973 cites W1574786337 @default.
- W4291666973 cites W1884568409 @default.
- W4291666973 cites W1964196268 @default.
- W4291666973 cites W1965555277 @default.
- W4291666973 cites W1969480244 @default.
- W4291666973 cites W1972564752 @default.
- W4291666973 cites W1978481500 @default.
- W4291666973 cites W1979455727 @default.
- W4291666973 cites W1980776397 @default.
- W4291666973 cites W1981982902 @default.
- W4291666973 cites W1983885921 @default.
- W4291666973 cites W1984431746 @default.
- W4291666973 cites W1988547834 @default.
- W4291666973 cites W1991236735 @default.
- W4291666973 cites W1993417422 @default.
- W4291666973 cites W1995110821 @default.
- W4291666973 cites W1995214286 @default.
- W4291666973 cites W1995875735 @default.
- W4291666973 cites W2001488773 @default.
- W4291666973 cites W2002882646 @default.
- W4291666973 cites W2007442047 @default.
- W4291666973 cites W2009480086 @default.
- W4291666973 cites W2013001152 @default.
- W4291666973 cites W2013683512 @default.
- W4291666973 cites W2028263740 @default.
- W4291666973 cites W2028825471 @default.
- W4291666973 cites W2033708181 @default.
- W4291666973 cites W2033942763 @default.
- W4291666973 cites W2039546655 @default.
- W4291666973 cites W2040246407 @default.
- W4291666973 cites W2042738987 @default.
- W4291666973 cites W2043448125 @default.
- W4291666973 cites W2044236359 @default.
- W4291666973 cites W2046056819 @default.
- W4291666973 cites W2047057213 @default.
- W4291666973 cites W2048142524 @default.
- W4291666973 cites W2054964683 @default.
- W4291666973 cites W2056746865 @default.
- W4291666973 cites W2058279623 @default.
- W4291666973 cites W2058395097 @default.
- W4291666973 cites W2060864576 @default.
- W4291666973 cites W2068098127 @default.
- W4291666973 cites W2070218409 @default.
- W4291666973 cites W2072862584 @default.
- W4291666973 cites W2076457657 @default.
- W4291666973 cites W2078731619 @default.
- W4291666973 cites W2083115933 @default.
- W4291666973 cites W2086028445 @default.
- W4291666973 cites W2087615164 @default.
- W4291666973 cites W2090232805 @default.
- W4291666973 cites W2090500269 @default.
- W4291666973 cites W2090763917 @default.
- W4291666973 cites W2092704770 @default.
- W4291666973 cites W2098534820 @default.
- W4291666973 cites W2102810982 @default.
- W4291666973 cites W2105190393 @default.
- W4291666973 cites W2113867800 @default.
- W4291666973 cites W2117268822 @default.
- W4291666973 cites W2117726420 @default.
- W4291666973 cites W2120222754 @default.
- W4291666973 cites W2121867616 @default.
- W4291666973 cites W2122419439 @default.
- W4291666973 cites W2122527187 @default.
- W4291666973 cites W2124103130 @default.
- W4291666973 cites W2124537291 @default.
- W4291666973 cites W2126449078 @default.
- W4291666973 cites W2128562176 @default.
- W4291666973 cites W2129046573 @default.
- W4291666973 cites W2132807882 @default.
- W4291666973 cites W2133877521 @default.
- W4291666973 cites W2135838918 @default.
- W4291666973 cites W2137973279 @default.
- W4291666973 cites W2140986639 @default.
- W4291666973 cites W2147130840 @default.
- W4291666973 cites W2147263781 @default.
- W4291666973 cites W2148764920 @default.
- W4291666973 cites W2154579172 @default.
- W4291666973 cites W2157033237 @default.
- W4291666973 cites W2158420012 @default.
- W4291666973 cites W2161389006 @default.
- W4291666973 cites W2163680698 @default.
- W4291666973 cites W2164005512 @default.
- W4291666973 cites W2165073330 @default.
- W4291666973 cites W2166219456 @default.
- W4291666973 cites W2167125619 @default.
- W4291666973 cites W2167243746 @default.
- W4291666973 cites W2168442233 @default.