FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4291711290> ?p ?o ?g. }

• W4291711290 endingPage "151" @default.
• W4291711290 startingPage "146" @default.
• W4291711290 abstract "Extracellular vesicles (EVs) are particles released from most cell types delimited by a lipid bilayer. Small EVs (sEVs) are nanosized (<200 nm) and include exosomes. Brain-derived sEVs may provide a source for new biomarkers of brain status. CD9, CD63, and CD81 are major members of the tetraspanin family frequently used as sEV markers. However, according to a recent report, tetraspanins were not equally expressed in all sEVs, but rather show heterogeneity that reflects the expression levels in their secretory cells. We therefore investigated tetraspanin heterogeneity of sEVs in biofluids commonly used for clinical laboratory tests, and those in the brain. Expression levels and distributions of CD9, CD63 and CD81 on sEVs were determined in serum, plasma, and cerebrospinal fluid (CSF) samples collected from each healthy donor, and in post-mortem brain tissue samples. We found heterogeneous mixes of sEVs with various tetraspanin combinations among sEVs, and the predominant types and heterogeneous patterns of tetraspanins were specific to sample type. Hierarchical clustering revealed that brain sEVs were similar to those in the CSF, but different from those in peripheral blood. Our findings both provide basic information and contribute to the development of biomarkers for neurological and psychiatric disorders." @default.
• W4291711290 created "2022-08-16" @default.
• W4291711290 creator A5026489862 @default.
• W4291711290 creator A5046095148 @default.
• W4291711290 creator A5069223833 @default.
• W4291711290 creator A5073047222 @default.
• W4291711290 creator A5074812879 @default.
• W4291711290 creator A5086724485 @default.
• W4291711290 date "2022-10-01" @default.
• W4291711290 modified "2023-10-13" @default.
• W4291711290 title "Tetraspanin heterogeneity of small extracellular vesicles in human biofluids and brain tissue" @default.
• W4291711290 cites W1607207125 @default.
• W4291711290 cites W1986820887 @default.
• W4291711290 cites W2014655626 @default.
• W4291711290 cites W2028248159 @default.
• W4291711290 cites W2052950175 @default.
• W4291711290 cites W2055313665 @default.
• W4291711290 cites W2123614057 @default.
• W4291711290 cites W2153840858 @default.
• W4291711290 cites W2155366992 @default.
• W4291711290 cites W2168569509 @default.
• W4291711290 cites W2169977305 @default.
• W4291711290 cites W2252291791 @default.
• W4291711290 cites W2296538017 @default.
• W4291711290 cites W2549542099 @default.
• W4291711290 cites W2925523925 @default.
• W4291711290 cites W2978384597 @default.
• W4291711290 cites W3005104290 @default.
• W4291711290 cites W3127124119 @default.
• W4291711290 cites W3168265815 @default.
• W4291711290 cites W3182263078 @default.
• W4291711290 cites W4226341702 @default.
• W4291711290 doi "https://doi.org/10.1016/j.bbrc.2022.08.025" @default.
• W4291711290 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36037746" @default.
• W4291711290 hasPublicationYear "2022" @default.
• W4291711290 type Work @default.
• W4291711290 citedByCount "1" @default.
• W4291711290 countsByYear W42917112902023 @default.
• W4291711290 crossrefType "journal-article" @default.
• W4291711290 hasAuthorship W4291711290A5026489862 @default.
• W4291711290 hasAuthorship W4291711290A5046095148 @default.
• W4291711290 hasAuthorship W4291711290A5069223833 @default.
• W4291711290 hasAuthorship W4291711290A5073047222 @default.
• W4291711290 hasAuthorship W4291711290A5074812879 @default.
• W4291711290 hasAuthorship W4291711290A5086724485 @default.
• W4291711290 hasConcept C104317684 @default.
• W4291711290 hasConcept C145059251 @default.
• W4291711290 hasConcept C1491633281 @default.
• W4291711290 hasConcept C169760540 @default.
• W4291711290 hasConcept C203014093 @default.
• W4291711290 hasConcept C20518536 @default.
• W4291711290 hasConcept C2522874641 @default.
• W4291711290 hasConcept C2776385711 @default.
• W4291711290 hasConcept C2776408679 @default.
• W4291711290 hasConcept C2776507628 @default.
• W4291711290 hasConcept C2777208748 @default.
• W4291711290 hasConcept C2777670902 @default.
• W4291711290 hasConcept C2781261824 @default.
• W4291711290 hasConcept C28406088 @default.
• W4291711290 hasConcept C2909763251 @default.
• W4291711290 hasConcept C2986936838 @default.
• W4291711290 hasConcept C2992929900 @default.
• W4291711290 hasConcept C55493867 @default.
• W4291711290 hasConcept C86803240 @default.
• W4291711290 hasConcept C95444343 @default.
• W4291711290 hasConceptScore W4291711290C104317684 @default.
• W4291711290 hasConceptScore W4291711290C145059251 @default.
• W4291711290 hasConceptScore W4291711290C1491633281 @default.
• W4291711290 hasConceptScore W4291711290C169760540 @default.
• W4291711290 hasConceptScore W4291711290C203014093 @default.
• W4291711290 hasConceptScore W4291711290C20518536 @default.
• W4291711290 hasConceptScore W4291711290C2522874641 @default.
• W4291711290 hasConceptScore W4291711290C2776385711 @default.
• W4291711290 hasConceptScore W4291711290C2776408679 @default.
• W4291711290 hasConceptScore W4291711290C2776507628 @default.
• W4291711290 hasConceptScore W4291711290C2777208748 @default.
• W4291711290 hasConceptScore W4291711290C2777670902 @default.
• W4291711290 hasConceptScore W4291711290C2781261824 @default.
• W4291711290 hasConceptScore W4291711290C28406088 @default.
• W4291711290 hasConceptScore W4291711290C2909763251 @default.
• W4291711290 hasConceptScore W4291711290C2986936838 @default.
• W4291711290 hasConceptScore W4291711290C2992929900 @default.
• W4291711290 hasConceptScore W4291711290C55493867 @default.
• W4291711290 hasConceptScore W4291711290C86803240 @default.
• W4291711290 hasConceptScore W4291711290C95444343 @default.
• W4291711290 hasFunder F4320334764 @default.
• W4291711290 hasLocation W42917112901 @default.
• W4291711290 hasLocation W42917112902 @default.
• W4291711290 hasOpenAccess W4291711290 @default.
• W4291711290 hasPrimaryLocation W42917112901 @default.
• W4291711290 hasRelatedWork W1564625417 @default.
• W4291711290 hasRelatedWork W2158303756 @default.
• W4291711290 hasRelatedWork W2923297188 @default.
• W4291711290 hasRelatedWork W2967533447 @default.
• W4291711290 hasRelatedWork W3103350646 @default.
• W4291711290 hasRelatedWork W4291711290 @default.
• W4291711290 hasRelatedWork W4307282616 @default.
• W4291711290 hasRelatedWork W4310592778 @default.

• next