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- W4291732098 endingPage "114482" @default.
- W4291732098 startingPage "114482" @default.
- W4291732098 abstract "• Progress of preclinical and clinical research into engineered nanomedicine is helping to bring new effective diagnostic and therapeutic approaches to cancer patients. • Biomarker-driven engineered nanoparticles offer enhanced cancer-specific and personalized therapy. • Engineered nanoparticles represent an efficient tool to deliver different types of treatments for patients with difficult-to-treat cancers. • Surface-engineered nanoparticles have the potential to overcome the physical and biological barriers that are known to limit the effectiveness of unmodified or unfunctionalized nanoparticles. Over the past two decades, multidisciplinary investigations into the development of nanoparticles for medical applications have continually increased. However, nanoparticles are still subject to biological barriers and biodistribution challenges, which limit their overall clinical potential. This has motivated the implementation of innovational modifications to a range of nanoparticle formulations designed for cancer imaging and/or cancer treatment to overcome specific barriers and shift the accumulation of payloads toward the diseased tissues. In recent years, novel technological and chemical approaches have been employed to modify or functionalize the surface of nanoparticles or manipulate the characteristics of nanoparticles. Combining these approaches with the identification of critical biomarkers provides new strategies for enhancing nanoparticle specificity for both cancer diagnostic and therapeutic applications. This review discusses the most recent advances in the design and engineering of nanoparticles as well as future directions for developing the next generation of nanomedicines." @default.
- W4291732098 created "2022-08-16" @default.
- W4291732098 creator A5002551319 @default.
- W4291732098 creator A5064722874 @default.
- W4291732098 creator A5081066169 @default.
- W4291732098 date "2022-10-01" @default.
- W4291732098 modified "2023-10-12" @default.
- W4291732098 title "Engineering nanosystems to overcome barriers to cancer diagnosis and treatment" @default.
- W4291732098 cites W1409677094 @default.
- W4291732098 cites W1420516430 @default.
- W4291732098 cites W1505632988 @default.
- W4291732098 cites W1547512877 @default.
- W4291732098 cites W1582589071 @default.
- W4291732098 cites W1591560031 @default.
- W4291732098 cites W1598525939 @default.
- W4291732098 cites W1843302206 @default.
- W4291732098 cites W1861980204 @default.
- W4291732098 cites W1914241837 @default.
- W4291732098 cites W1964937406 @default.
- W4291732098 cites W1965538863 @default.
- W4291732098 cites W1972176139 @default.
- W4291732098 cites W1974702735 @default.
- W4291732098 cites W1977016792 @default.
- W4291732098 cites W1977569722 @default.
- W4291732098 cites W1979309097 @default.
- W4291732098 cites W1982381743 @default.
- W4291732098 cites W1983394230 @default.
- W4291732098 cites W1984133121 @default.
- W4291732098 cites W1988587530 @default.
- W4291732098 cites W1992945709 @default.
- W4291732098 cites W1993231275 @default.
- W4291732098 cites W1994787250 @default.
- W4291732098 cites W2000417831 @default.
- W4291732098 cites W2002162019 @default.
- W4291732098 cites W2003867647 @default.
- W4291732098 cites W2004738363 @default.
- W4291732098 cites W2004934153 @default.
- W4291732098 cites W2005882563 @default.
- W4291732098 cites W2007553857 @default.
- W4291732098 cites W2008579070 @default.
- W4291732098 cites W2008834586 @default.
- W4291732098 cites W2011030869 @default.
- W4291732098 cites W2011975682 @default.
- W4291732098 cites W2012112777 @default.
- W4291732098 cites W2014910913 @default.
- W4291732098 cites W2018614615 @default.
- W4291732098 cites W2025869556 @default.
- W4291732098 cites W2027949644 @default.
- W4291732098 cites W2032641449 @default.
- W4291732098 cites W2035743945 @default.
- W4291732098 cites W2038321556 @default.
- W4291732098 cites W2038717222 @default.
- W4291732098 cites W2038998098 @default.
- W4291732098 cites W2039551908 @default.
- W4291732098 cites W2040223159 @default.
- W4291732098 cites W2042990492 @default.
- W4291732098 cites W2043371238 @default.
- W4291732098 cites W2047802522 @default.
- W4291732098 cites W2050862293 @default.
- W4291732098 cites W2054842174 @default.
- W4291732098 cites W2054909969 @default.
- W4291732098 cites W2055494875 @default.
- W4291732098 cites W2055818374 @default.
- W4291732098 cites W2056451867 @default.
- W4291732098 cites W2058208078 @default.
- W4291732098 cites W2060372515 @default.
- W4291732098 cites W2060459188 @default.
- W4291732098 cites W2061775664 @default.
- W4291732098 cites W2062244504 @default.
- W4291732098 cites W2067848116 @default.
- W4291732098 cites W2074544404 @default.
- W4291732098 cites W2074607936 @default.
- W4291732098 cites W2076226743 @default.
- W4291732098 cites W2077250280 @default.
- W4291732098 cites W2078454159 @default.
- W4291732098 cites W2080182688 @default.
- W4291732098 cites W2081263253 @default.
- W4291732098 cites W2085470629 @default.
- W4291732098 cites W2087705699 @default.
- W4291732098 cites W2088014532 @default.
- W4291732098 cites W2091233468 @default.
- W4291732098 cites W2093149504 @default.
- W4291732098 cites W2094516614 @default.
- W4291732098 cites W2099487193 @default.
- W4291732098 cites W2101657078 @default.
- W4291732098 cites W2102720425 @default.
- W4291732098 cites W2103433377 @default.
- W4291732098 cites W2105553762 @default.
- W4291732098 cites W2105812125 @default.
- W4291732098 cites W2108795463 @default.
- W4291732098 cites W2109061692 @default.
- W4291732098 cites W2109626691 @default.
- W4291732098 cites W2109858016 @default.
- W4291732098 cites W2110231369 @default.
- W4291732098 cites W2110482491 @default.
- W4291732098 cites W2113309596 @default.
- W4291732098 cites W2113727201 @default.
- W4291732098 cites W2115112079 @default.