FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4291743997> ?p ?o ?g. }

• W4291743997 endingPage "5747" @default.
• W4291743997 startingPage "5731" @default.
• W4291743997 abstract "Background: This study aims to evaluate the overall and breast cancer-specific survival (BCSS) after breast-conserving surgery (BCS) plus radiotherapy (RT) compared with mastectomy plus RT in resectable breast cancer. Moreover, the aim is to also identify the subgroups who benefit from BCS plus RT and establish a predictive nomogram for stage II patients. Methods: Stage I−III breast cancer patients were identified from the Surveillance, Epidemiology, and End Results (SEER) database between 1990 and 2016. Patients with available clinical information were split into two groups: BCS plus RT and mastectomy plus RT. Kaplan−Meier survival analysis, univariate and multivariate regression analysis, and propensity score matching were used in the study. Hazard ratio (HR) was calculated based on stratified Cox univariate regression analyses. A prognostic nomogram by multivariable Cox regression model was developed for stage II patients, and consistency index (C-index) and calibration curve were used to evaluate the accuracy of the nomogram in the training and validation set. Results: A total of 24,590 eligible patients were enrolled. The difference in overall survival (OS) and BCSS remained significant in stage II patients both before and after PSM (after PSM: OS: HR = 0.8536, p = 0.0115; BCSS: HR = 0.7803, p = 0.0013). In stage II patients, the survival advantage effect of BCS plus RT on OS and BCSS was observed in the following subgroups: any age, smaller tumor size (<1 cm), stage IIA (T2N0, T0−1N1), ER (+), and any PR status. Secondly, the C-indexes for BCSS prediction was 0.714 (95% CI 0.694−0.734). The calibration curves showed perfect agreement in both the training and validation sets. Conclusions: BCS plus RT significantly improved the survival rates for patients of stage IIA (T2N0, T0−1N1), ER (+). For stage II patients, the nomogram was a good predictor of 5-, 10-, and 15-year BCSS. Our study may help guide treatment decisions and prolong the survival of stage II breast cancer patients." @default.
• W4291743997 created "2022-08-16" @default.
• W4291743997 creator A5011360264 @default.
• W4291743997 creator A5011544068 @default.
• W4291743997 creator A5027953387 @default.
• W4291743997 creator A5028674996 @default.
• W4291743997 creator A5031609490 @default.
• W4291743997 creator A5089343074 @default.
• W4291743997 date "2022-08-15" @default.
• W4291743997 modified "2023-10-12" @default.
• W4291743997 title "Survival Comparisons between Breast Conservation Surgery and Mastectomy Followed by Postoperative Radiotherapy in Stage I–III Breast Cancer Patients: Analysis of the Surveillance, Epidemiology, and End Results (Seer) Program Database" @default.
• W4291743997 cites W1017651675 @default.
• W4291743997 cites W1782647475 @default.
• W4291743997 cites W2013188491 @default.
• W4291743997 cites W2036193982 @default.
• W4291743997 cites W2042250837 @default.
• W4291743997 cites W2067115868 @default.
• W4291743997 cites W2067420088 @default.
• W4291743997 cites W2104441156 @default.
• W4291743997 cites W2130746306 @default.
• W4291743997 cites W2136488739 @default.
• W4291743997 cites W2140043363 @default.
• W4291743997 cites W2150291618 @default.
• W4291743997 cites W2152156802 @default.
• W4291743997 cites W2328460741 @default.
• W4291743997 cites W2467949803 @default.
• W4291743997 cites W2521999419 @default.
• W4291743997 cites W2800678179 @default.
• W4291743997 cites W2803832675 @default.
• W4291743997 cites W2809297981 @default.
• W4291743997 cites W2809908448 @default.
• W4291743997 cites W2902329469 @default.
• W4291743997 cites W2911526204 @default.
• W4291743997 cites W2913728083 @default.
• W4291743997 cites W2945415599 @default.
• W4291743997 cites W2959821759 @default.
• W4291743997 cites W2965592828 @default.
• W4291743997 cites W2965857754 @default.
• W4291743997 cites W3091856482 @default.
• W4291743997 cites W3108374973 @default.
• W4291743997 cites W3122112533 @default.
• W4291743997 cites W3157699994 @default.
• W4291743997 cites W3159926967 @default.
• W4291743997 cites W4300196633 @default.
• W4291743997 cites W4319290974 @default.
• W4291743997 doi "https://doi.org/10.3390/curroncol29080452" @default.
• W4291743997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36005190" @default.
• W4291743997 hasPublicationYear "2022" @default.
• W4291743997 type Work @default.
• W4291743997 citedByCount "3" @default.
• W4291743997 countsByYear W42917439972022 @default.
• W4291743997 countsByYear W42917439972023 @default.
• W4291743997 crossrefType "journal-article" @default.
• W4291743997 hasAuthorship W4291743997A5011360264 @default.
• W4291743997 hasAuthorship W4291743997A5011544068 @default.
• W4291743997 hasAuthorship W4291743997A5027953387 @default.
• W4291743997 hasAuthorship W4291743997A5028674996 @default.
• W4291743997 hasAuthorship W4291743997A5031609490 @default.
• W4291743997 hasAuthorship W4291743997A5089343074 @default.
• W4291743997 hasBestOaLocation W42917439971 @default.
• W4291743997 hasConcept C107130276 @default.
• W4291743997 hasConcept C121608353 @default.
• W4291743997 hasConcept C126322002 @default.
• W4291743997 hasConcept C143998085 @default.
• W4291743997 hasConcept C144301174 @default.
• W4291743997 hasConcept C146357865 @default.
• W4291743997 hasConcept C151730666 @default.
• W4291743997 hasConcept C17923572 @default.
• W4291743997 hasConcept C207103383 @default.
• W4291743997 hasConcept C2777757722 @default.
• W4291743997 hasConcept C2778527826 @default.
• W4291743997 hasConcept C2779391198 @default.
• W4291743997 hasConcept C2781467025 @default.
• W4291743997 hasConcept C29456083 @default.
• W4291743997 hasConcept C34626388 @default.
• W4291743997 hasConcept C38180746 @default.
• W4291743997 hasConcept C44249647 @default.
• W4291743997 hasConcept C50382708 @default.
• W4291743997 hasConcept C509974204 @default.
• W4291743997 hasConcept C530470458 @default.
• W4291743997 hasConcept C71924100 @default.
• W4291743997 hasConcept C86803240 @default.
• W4291743997 hasConceptScore W4291743997C107130276 @default.
• W4291743997 hasConceptScore W4291743997C121608353 @default.
• W4291743997 hasConceptScore W4291743997C126322002 @default.
• W4291743997 hasConceptScore W4291743997C143998085 @default.
• W4291743997 hasConceptScore W4291743997C144301174 @default.
• W4291743997 hasConceptScore W4291743997C146357865 @default.
• W4291743997 hasConceptScore W4291743997C151730666 @default.
• W4291743997 hasConceptScore W4291743997C17923572 @default.
• W4291743997 hasConceptScore W4291743997C207103383 @default.
• W4291743997 hasConceptScore W4291743997C2777757722 @default.
• W4291743997 hasConceptScore W4291743997C2778527826 @default.
• W4291743997 hasConceptScore W4291743997C2779391198 @default.
• W4291743997 hasConceptScore W4291743997C2781467025 @default.
• W4291743997 hasConceptScore W4291743997C29456083 @default.
• W4291743997 hasConceptScore W4291743997C34626388 @default.
• W4291743997 hasConceptScore W4291743997C38180746 @default.

• next