Matches in SemOpenAlex for { <https://semopenalex.org/work/W4291892149> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4291892149 abstract "Abstract Recent advances in sequencing and bioinformatics have expanded the tree of life by providing genomes for uncultured environmentally relevant clades, either through metagenome-assembled genomes or through single-cell genomes. While this expanded diversity can provide novel insights into microbial population structure, most tools available for core-genome estimation are sensitive to genome completeness. Consequently, a major portion of the huge phylogenetic diversity uncovered by environmental genomic approaches remains excluded from such analyses. We present mOTUpan, a novel iterative Bayesian method for computing the core genome for sets of genomes of highly diverse completeness range. The likelihood for each gene cluster to belong to core or accessory genome is estimated by computing the probability of its presence/absence pattern in the target genome set. The core-genome prediction is computationally efficient and can be scaled up to thousands of genomes. It has shown comparable estimates to state-of-the-art tools Roary and PPanGGOLiN for high-quality genomes and is capable of using genomes at lower completeness thresholds. mOTUpan wraps a bootstrapping procedure to estimate the quality of a specific core-genome prediction, as the accuracy of each run will depend on the specific completeness distribution and the number of genomes in the dataset under scrutiny. mOTUpan is implemented in the mOTUlizer software package, and available at github.com/moritzbuck/mOTUlizer, under GPL 3.0 license." @default.
- W4291892149 created "2022-08-16" @default.
- W4291892149 creator A5029716031 @default.
- W4291892149 creator A5057055718 @default.
- W4291892149 creator A5065855611 @default.
- W4291892149 date "2022-07-09" @default.
- W4291892149 modified "2023-10-17" @default.
- W4291892149 title "mOTUpan: a robust Bayesian approach to leverage metagenome-assembled genomes for core-genome estimation" @default.
- W4291892149 cites W1966984343 @default.
- W4291892149 cites W2011399877 @default.
- W4291892149 cites W2055615325 @default.
- W4291892149 cites W2069601176 @default.
- W4291892149 cites W2112364185 @default.
- W4291892149 cites W2122673596 @default.
- W4291892149 cites W2160199722 @default.
- W4291892149 cites W2315521535 @default.
- W4291892149 cites W2344821303 @default.
- W4291892149 cites W2784407026 @default.
- W4291892149 cites W2908796034 @default.
- W4291892149 cites W2950954328 @default.
- W4291892149 cites W2982249296 @default.
- W4291892149 cites W2986925300 @default.
- W4291892149 cites W2995063445 @default.
- W4291892149 cites W3012393121 @default.
- W4291892149 cites W3019706413 @default.
- W4291892149 cites W3104596207 @default.
- W4291892149 cites W3116000462 @default.
- W4291892149 cites W3119969522 @default.
- W4291892149 cites W3161138487 @default.
- W4291892149 cites W3203343200 @default.
- W4291892149 doi "https://doi.org/10.1093/nargab/lqac060" @default.
- W4291892149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35979445" @default.
- W4291892149 hasPublicationYear "2022" @default.
- W4291892149 type Work @default.
- W4291892149 citedByCount "3" @default.
- W4291892149 countsByYear W42918921492022 @default.
- W4291892149 countsByYear W42918921492023 @default.
- W4291892149 crossrefType "journal-article" @default.
- W4291892149 hasAuthorship W4291892149A5029716031 @default.
- W4291892149 hasAuthorship W4291892149A5057055718 @default.
- W4291892149 hasAuthorship W4291892149A5065855611 @default.
- W4291892149 hasBestOaLocation W42918921491 @default.
- W4291892149 hasConcept C104317684 @default.
- W4291892149 hasConcept C107673813 @default.
- W4291892149 hasConcept C119857082 @default.
- W4291892149 hasConcept C124101348 @default.
- W4291892149 hasConcept C141231307 @default.
- W4291892149 hasConcept C15151743 @default.
- W4291892149 hasConcept C153083717 @default.
- W4291892149 hasConcept C154945302 @default.
- W4291892149 hasConcept C189206191 @default.
- W4291892149 hasConcept C193252679 @default.
- W4291892149 hasConcept C3742359 @default.
- W4291892149 hasConcept C41008148 @default.
- W4291892149 hasConcept C54355233 @default.
- W4291892149 hasConcept C70721500 @default.
- W4291892149 hasConcept C86803240 @default.
- W4291892149 hasConceptScore W4291892149C104317684 @default.
- W4291892149 hasConceptScore W4291892149C107673813 @default.
- W4291892149 hasConceptScore W4291892149C119857082 @default.
- W4291892149 hasConceptScore W4291892149C124101348 @default.
- W4291892149 hasConceptScore W4291892149C141231307 @default.
- W4291892149 hasConceptScore W4291892149C15151743 @default.
- W4291892149 hasConceptScore W4291892149C153083717 @default.
- W4291892149 hasConceptScore W4291892149C154945302 @default.
- W4291892149 hasConceptScore W4291892149C189206191 @default.
- W4291892149 hasConceptScore W4291892149C193252679 @default.
- W4291892149 hasConceptScore W4291892149C3742359 @default.
- W4291892149 hasConceptScore W4291892149C41008148 @default.
- W4291892149 hasConceptScore W4291892149C54355233 @default.
- W4291892149 hasConceptScore W4291892149C70721500 @default.
- W4291892149 hasConceptScore W4291892149C86803240 @default.
- W4291892149 hasFunder F4320322581 @default.
- W4291892149 hasIssue "3" @default.
- W4291892149 hasLocation W42918921491 @default.
- W4291892149 hasLocation W42918921492 @default.
- W4291892149 hasLocation W42918921493 @default.
- W4291892149 hasLocation W42918921494 @default.
- W4291892149 hasLocation W42918921495 @default.
- W4291892149 hasOpenAccess W4291892149 @default.
- W4291892149 hasPrimaryLocation W42918921491 @default.
- W4291892149 hasRelatedWork W2001561488 @default.
- W4291892149 hasRelatedWork W2127106003 @default.
- W4291892149 hasRelatedWork W2340204314 @default.
- W4291892149 hasRelatedWork W2795964999 @default.
- W4291892149 hasRelatedWork W3090971826 @default.
- W4291892149 hasRelatedWork W4231204000 @default.
- W4291892149 hasRelatedWork W4237336638 @default.
- W4291892149 hasRelatedWork W4247428816 @default.
- W4291892149 hasRelatedWork W4249521745 @default.
- W4291892149 hasRelatedWork W4253237236 @default.
- W4291892149 hasVolume "4" @default.
- W4291892149 isParatext "false" @default.
- W4291892149 isRetracted "false" @default.
- W4291892149 workType "article" @default.