FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292014142> ?p ?o ?g. }

• W4292014142 abstract "Abstract With the ever-increasing shortage of kidney donors, transplant centers are faced with the challenge of finding ways to maximize their use of all available organ resources and extend the donor pool, including the use of expanded criteria donors. To address the need for a new analytical solution for graft quality assessments, we present a novel biochemical analysis method based on solid-phase microextraction (SPME) – a chemical biopsy. In this study, renal autotransplantation was performed in porcine models to simulate two types of donor scenarios: heart beating donors (HBD) and donors after cardiac death (DCD). All renal grafts were perfused using continuous normothermic ex vivo kidney perfusion. The small diameter of SPME probes enables minimally invasive and repeated sampling of the same tissue, thus allowing changes occurring in the organ to be tracked throughout the entire transplantation procedure. Samples were subjected to metabolomic and lipidomic profiling using high-performance liquid chromatography coupled with a mass spectrometer. As a result, we observed differences in the profiles of HBD and DCD kidneys. The most pronounced alterations were reflected in the levels of essential amino acids, purine nucleosides, lysophosphocholines, phosphoethanolamines, and triacylglycerols. Our findings demonstrate the potential of chemical biopsy in donor graft quality assessment and monitoring kidney function during perfusion." @default.
• W4292014142 created "2022-08-17" @default.
• W4292014142 creator A5017457722 @default.
• W4292014142 creator A5044551220 @default.
• W4292014142 creator A5048747053 @default.
• W4292014142 creator A5060467984 @default.
• W4292014142 creator A5074491754 @default.
• W4292014142 creator A5076315344 @default.
• W4292014142 date "2022-08-16" @default.
• W4292014142 modified "2023-10-17" @default.
• W4292014142 title "Metabolomic and lipidomic landscape of porcine kidney associated with kidney perfusion in heart beating donors and donors after cardiac death" @default.
• W4292014142 cites W1483538456 @default.
• W4292014142 cites W1962648987 @default.
• W4292014142 cites W1989234276 @default.
• W4292014142 cites W2050948973 @default.
• W4292014142 cites W2081493694 @default.
• W4292014142 cites W2096282875 @default.
• W4292014142 cites W2098397904 @default.
• W4292014142 cites W2131374919 @default.
• W4292014142 cites W2159756628 @default.
• W4292014142 cites W2159759437 @default.
• W4292014142 cites W2290531317 @default.
• W4292014142 cites W2290567590 @default.
• W4292014142 cites W2314169751 @default.
• W4292014142 cites W2320708895 @default.
• W4292014142 cites W2333793246 @default.
• W4292014142 cites W2357691645 @default.
• W4292014142 cites W2380380353 @default.
• W4292014142 cites W2411561471 @default.
• W4292014142 cites W2479603702 @default.
• W4292014142 cites W2523430665 @default.
• W4292014142 cites W2567980763 @default.
• W4292014142 cites W2591623930 @default.
• W4292014142 cites W2596441513 @default.
• W4292014142 cites W2605431828 @default.
• W4292014142 cites W2751090440 @default.
• W4292014142 cites W2764067490 @default.
• W4292014142 cites W2767489832 @default.
• W4292014142 cites W2770428667 @default.
• W4292014142 cites W2792724422 @default.
• W4292014142 cites W2794865171 @default.
• W4292014142 cites W2802899333 @default.
• W4292014142 cites W2896335144 @default.
• W4292014142 cites W2907472418 @default.
• W4292014142 cites W2914465484 @default.
• W4292014142 cites W2918776917 @default.
• W4292014142 cites W2935629414 @default.
• W4292014142 cites W2940769160 @default.
• W4292014142 cites W2964346664 @default.
• W4292014142 cites W2968645588 @default.
• W4292014142 cites W2974257765 @default.
• W4292014142 cites W2978061158 @default.
• W4292014142 cites W2987825845 @default.
• W4292014142 cites W2995770912 @default.
• W4292014142 cites W3001041655 @default.
• W4292014142 cites W3007944970 @default.
• W4292014142 cites W3035779964 @default.
• W4292014142 cites W3038936175 @default.
• W4292014142 cites W3083947325 @default.
• W4292014142 cites W3087383854 @default.
• W4292014142 cites W4226081802 @default.
• W4292014142 cites W4239111638 @default.
• W4292014142 doi "https://doi.org/10.21203/rs.3.rs-1948944/v1" @default.
• W4292014142 hasPublicationYear "2022" @default.
• W4292014142 type Work @default.
• W4292014142 citedByCount "2" @default.
• W4292014142 countsByYear W42920141422023 @default.
• W4292014142 crossrefType "posted-content" @default.
• W4292014142 hasAuthorship W4292014142A5017457722 @default.
• W4292014142 hasAuthorship W4292014142A5044551220 @default.
• W4292014142 hasAuthorship W4292014142A5048747053 @default.
• W4292014142 hasAuthorship W4292014142A5060467984 @default.
• W4292014142 hasAuthorship W4292014142A5074491754 @default.
• W4292014142 hasAuthorship W4292014142A5076315344 @default.
• W4292014142 hasBestOaLocation W42920141421 @default.
• W4292014142 hasConcept C126322002 @default.
• W4292014142 hasConcept C138885662 @default.
• W4292014142 hasConcept C146957229 @default.
• W4292014142 hasConcept C150903083 @default.
• W4292014142 hasConcept C181199279 @default.
• W4292014142 hasConcept C185592680 @default.
• W4292014142 hasConcept C194051981 @default.
• W4292014142 hasConcept C207001950 @default.
• W4292014142 hasConcept C21565614 @default.
• W4292014142 hasConcept C26291073 @default.
• W4292014142 hasConcept C2776476023 @default.
• W4292014142 hasConcept C2778137410 @default.
• W4292014142 hasConcept C2780091579 @default.
• W4292014142 hasConcept C2780303639 @default.
• W4292014142 hasConcept C2911091166 @default.
• W4292014142 hasConcept C41895202 @default.
• W4292014142 hasConcept C55493867 @default.
• W4292014142 hasConcept C60644358 @default.
• W4292014142 hasConcept C71924100 @default.
• W4292014142 hasConcept C86803240 @default.
• W4292014142 hasConceptScore W4292014142C126322002 @default.
• W4292014142 hasConceptScore W4292014142C138885662 @default.
• W4292014142 hasConceptScore W4292014142C146957229 @default.
• W4292014142 hasConceptScore W4292014142C150903083 @default.
• W4292014142 hasConceptScore W4292014142C181199279 @default.

• next