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• W4292079461 endingPage "204062232211174" @default.
• W4292079461 startingPage "204062232211174" @default.
• W4292079461 abstract "Multichannel intraluminal impedance and pH-monitoring (MII-pH) is an essential testing modality for gastroesophageal reflux-induced chronic cough (GERC), while the existing diagnostic criteria still have some inherent defects. This study aimed to explore the diagnostic value of a direct and objective index, reflux episodes, and related parameters in MII-pH in different types of GERC.Patients with chronic cough suspected of gastroesophageal reflux disease who successfully received MII-pH were enrolled. The differences in MII-pH parameters were analyzed among patients with different etiologies and the predictive diagnostic value of reflux episodes and related parameters were analyzed in patients with GERC, acid GERC, and non-acid GERC, and compared with existing diagnostic criteria.A total of 190 patients with suspected GERC who underwent MII-pH were enrolled; 131 of these patients were finally diagnosed with GERC. When the reflux episodes were used to diagnose GERC, the area under the curve (AUC) was 0.684; when the acid reflux episodes and the ratio of acid reflux episodes were used to diagnose acid GERC, the AUCs were 0.769 and 0.854; when the non-acid reflux episodes and the ratio of non-acid reflux episodes were used to diagnose non-acid GERC, the AUCs were 0.735 and 0.705, respectively. When the non-acid reflux episodes > 58 and the proportion of non-acid reflux episodes > 68.18% were used alone or in combination to diagnose non-acid GERC, their diagnostic value was significantly better than SAP or SI (all ps < 0.05).The number of reflux episodes has a good diagnostic value for GERC, especially in the diagnosis of non-acid GERC." @default.
• W4292079461 created "2022-08-17" @default.
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• W4292079461 date "2022-01-01" @default.
• W4292079461 modified "2023-09-26" @default.
• W4292079461 title "Diagnostic value of reflux episodes in gastroesophageal reflux-induced chronic cough: a novel predictive indicator" @default.
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• W4292079461 doi "https://doi.org/10.1177/20406223221117455" @default.
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