Matches in SemOpenAlex for { <https://semopenalex.org/work/W4292139321> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4292139321 endingPage "91" @default.
- W4292139321 startingPage "1183" @default.
- W4292139321 abstract "Angiogenesis is one of the hallmarks of cancer. Among the identified angiogenic factors, vascular endothelial growth factor (VEGF) is a crucial regulator of angiogenesis in normal and malignant tissue. Increased expression of VEGF has been detected in most tumors of humans, and it is associated with increased risks of recurrence, metastasis, and death. Bevacizumab (Avastin), a recombinant humanized monoclonal antibody targeting VEGF, has been evaluated in various solid tumors. Some pivotal phase III trials demonstrated that the addition of bevacizumab to conventional chemotherapy showed a survival benefit with acceptable toxicity. The United States Food and Drug Administration approved the use of bevacizumab for patients with unresectable colorectal cancer and unresectable non-squamous, non small cell lung cancer. In April 2007, the Japanese Ministry of Health, Labour and Welfare approved bevacizumab for patients with unresectable colorectal cancer. The usage of bevacizumab will be stipulated in combination with 5-fluorouracil containing chemotherapy at a dose of 5 mg/kg or 10 mg/kg given every 14 days. To know its efficacy and safety of bevacizumab is necessary for Japanese patients in the clinical practice." @default.
- W4292139321 created "2022-08-17" @default.
- W4292139321 creator A5010090426 @default.
- W4292139321 creator A5038655401 @default.
- W4292139321 creator A5062748030 @default.
- W4292139321 date "2007-08-01" @default.
- W4292139321 modified "2023-10-16" @default.
- W4292139321 title "[Bevacizumab (Avastin)]." @default.
- W4292139321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17687199" @default.
- W4292139321 hasPublicationYear "2007" @default.
- W4292139321 type Work @default.
- W4292139321 citedByCount "0" @default.
- W4292139321 crossrefType "journal-article" @default.
- W4292139321 hasAuthorship W4292139321A5010090426 @default.
- W4292139321 hasAuthorship W4292139321A5038655401 @default.
- W4292139321 hasAuthorship W4292139321A5062748030 @default.
- W4292139321 hasConcept C121608353 @default.
- W4292139321 hasConcept C126322002 @default.
- W4292139321 hasConcept C143998085 @default.
- W4292139321 hasConcept C167734588 @default.
- W4292139321 hasConcept C2776056115 @default.
- W4292139321 hasConcept C2776256026 @default.
- W4292139321 hasConcept C2776694085 @default.
- W4292139321 hasConcept C2777025900 @default.
- W4292139321 hasConcept C2777802072 @default.
- W4292139321 hasConcept C2779013556 @default.
- W4292139321 hasConcept C2780394083 @default.
- W4292139321 hasConcept C526805850 @default.
- W4292139321 hasConcept C71924100 @default.
- W4292139321 hasConcept C98274493 @default.
- W4292139321 hasConceptScore W4292139321C121608353 @default.
- W4292139321 hasConceptScore W4292139321C126322002 @default.
- W4292139321 hasConceptScore W4292139321C143998085 @default.
- W4292139321 hasConceptScore W4292139321C167734588 @default.
- W4292139321 hasConceptScore W4292139321C2776056115 @default.
- W4292139321 hasConceptScore W4292139321C2776256026 @default.
- W4292139321 hasConceptScore W4292139321C2776694085 @default.
- W4292139321 hasConceptScore W4292139321C2777025900 @default.
- W4292139321 hasConceptScore W4292139321C2777802072 @default.
- W4292139321 hasConceptScore W4292139321C2779013556 @default.
- W4292139321 hasConceptScore W4292139321C2780394083 @default.
- W4292139321 hasConceptScore W4292139321C526805850 @default.
- W4292139321 hasConceptScore W4292139321C71924100 @default.
- W4292139321 hasConceptScore W4292139321C98274493 @default.
- W4292139321 hasIssue "8" @default.
- W4292139321 hasLocation W42921393211 @default.
- W4292139321 hasOpenAccess W4292139321 @default.
- W4292139321 hasPrimaryLocation W42921393211 @default.
- W4292139321 hasRelatedWork W1558845731 @default.
- W4292139321 hasRelatedWork W1967397018 @default.
- W4292139321 hasRelatedWork W1996418465 @default.
- W4292139321 hasRelatedWork W2039063316 @default.
- W4292139321 hasRelatedWork W2154369198 @default.
- W4292139321 hasRelatedWork W2302472031 @default.
- W4292139321 hasRelatedWork W2417464309 @default.
- W4292139321 hasRelatedWork W2966452281 @default.
- W4292139321 hasRelatedWork W3004639480 @default.
- W4292139321 hasRelatedWork W4280494735 @default.
- W4292139321 hasVolume "34" @default.
- W4292139321 isParatext "false" @default.
- W4292139321 isRetracted "false" @default.
- W4292139321 workType "article" @default.