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- W4292212725 abstract "Rare earth elements and their oxides are a new and exciting trend with potential applications in biomedicine. The praseodymium oxide (Pr 6 O 11 ) nanoparticles (NPs) are synthesized by a polyol method with the addition of ionic liquids (ILs) as a templating agent. The ILs 1-Butyl-3-methylimidazolium hexafluorophosphate (BMIM-PF 6 ) have been utilized to decrease particle growth by inhibiting nucleation. Ethylene glycol, a well-known polyol, was used as a solvent and stabilizing agent. The X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HR-TEM) analysis of Pr 6 O 11 (IL-PO) NPs synthesized with the assistance of BMIM-PF 6 ILs via polyol approach revealed a high degree of crystallinity with a defined crystalline size of 23 nm and a mean particle size of around 38 ± 2 nm. IL-PO NPs have outstanding antibacterial activity against Gram-negative bacteria K. pneumoniae (Zone of inhibition-34 mm dia.) and Gram-positive bacteria S. aureus (Zone of inhibition-29 mm dia.). Additionally, it has superior anticancer activity against the MCF-7 breast cancer cell line. IL-PO NPs have an estimated IC 50 of 35.83 μg/mL, which makes them ideal for use as a therapeutic agent. Based on our findings, we anticipate that IL-PO NPs can be used as an effective anticancer material, particularly in the treatment of MCF-7 breast cancer. • The morphologically improved rare earth Pr 6 O 11 was prepared using the polyol method. • The polyol approach offers high crystallinity with a defined crystalline structure. • The BMIM-PF6 ionic liquid controls the morphology and affords cube-shaped Pr 6 O 11 NPs. • It exhibited outstanding antibacterial activity against E. coli and S. aureus. • It also shows superior anticancer activity against the MCF-7 breast cancer cell line." @default.
- W4292212725 created "2022-08-18" @default.
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- W4292212725 date "2022-12-01" @default.
- W4292212725 modified "2023-09-27" @default.
- W4292212725 title "[BMIM]-PF6 ionic liquid mediated polyol synthesis of praseodymium (III) oxide nanoparticles: Physicochemical investigation and its interaction with bacterial and cancer cells" @default.
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- W4292212725 doi "https://doi.org/10.1016/j.ceramint.2022.08.140" @default.
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