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• W4292247017 endingPage "515" @default.
• W4292247017 startingPage "515" @default.
• W4292247017 abstract "Hydrogels are nowadays widely used in various biomedical applications, and show great potential for the making of devices such as biosensors, drug- delivery vectors, carriers, or matrices for cell cultures in tissue engineering, etc. In these applications, due to the irregular complex surface of the human body or its organs/structures, the devices are often designed with a small thickness, and are required to be flexible when attached to biological surfaces. The devices will deform as driven by human motion and under external loading. In terms of mechanical modeling, most of these devices can be abstracted as shells. In this paper, we propose a mixed graph-finite element method (FEM) phase field approach to model the fracture of curved shells composed of hydrogels, for biomedical applications. We present herein examples for the fracture of a wearable biosensor, a membrane-coated drug, and a matrix for a cell culture, each made of a hydrogel. Used in combination with experimental material testing, our method opens a new pathway to the efficient modeling of fracture in biomedical devices with surfaces of arbitrary curvature, helping in the design of devices with tunable fracture properties." @default.
• W4292247017 created "2022-08-19" @default.
• W4292247017 creator A5026423237 @default.
• W4292247017 creator A5029905806 @default.
• W4292247017 creator A5055790393 @default.
• W4292247017 creator A5062976895 @default.
• W4292247017 creator A5070234333 @default.
• W4292247017 date "2022-08-18" @default.
• W4292247017 modified "2023-10-14" @default.
• W4292247017 title "Modeling Tunable Fracture in Hydrogel Shell Structures for Biomedical Applications" @default.
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